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COL12A1 encodes the alpha chain of type XII collagen, a member of the FACIT (fibril-associated collagens with interrupted triple helices) collagen family. Additionally we are shipping and and many more products for this protein.
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In conclusion, the novel main finding of this study was a significant interaction between the COL5A1 (show COL5A1 ELISA Kits) rs12722 T/C and COL12A1 rs970547 A/G variants and risk of anterior cruciate ligament injury.
The study indicates that the spectrum of causative genes in extracellular matrix-related myopathies be extended to include COL12A1.
collagen alpha-1 (XII) chain was expressed at dramatically higher (~10-fold) levels in breast
COL3A1 (show COL3A1 ELISA Kits) rs1800255, COL6A1 (show COL6A1 ELISA Kits) rs35796750 and COL12A1 rs970547 were not significantly associated with sit-and-reach, straight leg raise or total shoulder rotation range of motion
In addition to binding collagen I, COMP (show COMP ELISA Kits) binds to collagens XII and XIV via their C-terminal collagenous domains.
COL12A1 is associated with anterior cruciate ligament ruptures among females
this study identifies COL12A1 as the likely gene candidate within the recurrent 6q13 breakpoint and provides an alternative approach for detecting 6q13 anomalies in nondividing cells of chondromyxoid fibroma.
both COL12A1 and COL4A5 (show COL4a5 ELISA Kits) constitute good candidate target genes in the pathogenesis of subungual exostosis
This gene encodes the alpha chain of type XII collagen, a member of the FACIT (fibril-associated collagens with interrupted triple helices) collagen family. Type XII collagen is a homotrimer found in association with type I collagen, an association that is thought to modify the interactions between collagen I fibrils and the surrounding matrix. Alternatively spliced transcript variants encoding different isoforms have been identified.
, collagen alpha-1(XII) chain
, collagen type XII alpha 1 chain
, type XII collagen
, collagen type XII proteoglycan