Collapsin Response Mediator Protein 1 Proteins (CRMP1)

CRMP1 encodes a member of a family of cytosolic phosphoproteins expressed exclusively in the nervous system. Additionally we are shipping CRMP1 Antibodies (108) and CRMP1 Kits (3) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
CRMP1 1400 Q14194
CRMP1 12933 P97427
Rat CRMP1 CRMP1 25415 Q62950
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Top CRMP1 Proteins at antibodies-online.com

Showing 10 out of 11 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Log in to see 10 to 12 Days
$785.40
Details
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 60 Days
$7,759.50
Details
Insect Cells Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 60 Days
$7,759.50
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 11 to 12 Days
$405.71
Details
HOST_Escherichia coli (E. coli) Human His tag   100 μg Log in to see 2 to 3 Days
$418.88
Details
HOST_Escherichia coli (E. coli) Human His tag   10 μg Log in to see 2 to 3 Days
$662.36
Details
HOST_Escherichia coli (E. coli) Human T7 tag,His tag   100 μg Log in to see 15 to 18 Days
$659.00
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   5 μg Log in to see 6 to 11 Days
$129.87
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   5 applications Log in to see 1 to 2 Days
$312.71
Details
Human Un-conjugated   5 μg Log in to see 6 Days
$550.39
Details

CRMP1 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , , ,
, , ,
Mouse (Murine) ,

Top referenced CRMP1 Proteins

  1. Human CRMP1 Protein expressed in HEK-293 Cells - ABIN2712565 : Braunschweig, Krakowiak, Duncanson, Boyce, Hansen, Ashwood, Hertz-Picciotto, Pessah, Van de Water: Autism-specific maternal autoantibodies recognize critical proteins in developing brain. in Translational psychiatry 2013 (PubMed)

More Proteins for Collapsin Response Mediator Protein 1 (CRMP1) Interaction Partners

Human Collapsin Response Mediator Protein 1 (CRMP1) interaction partners

  1. Study shows that CRMP1 acts an EMT and metastasis suppressor in prostate cancer cells via its regulation of actin polymerization.

  2. Identify CRMP-1 as a novel regulator of actin filament elongation and reveal a surprisingly important role for CRMP-1, EVL, and actin polymerization in maintaining the structural integrity of epithelial sheets.

  3. The present study reports that miR (show MLXIP Proteins)-187 was significantly overexpressed in gastric cancer tissues compared to that in non-tumor tissues and was associated with malignant clinical factors such as depth of invasion (P = 0.005), tumor size (P = 0.024), lymph node metastasis . It was found that collapsin response mediator protein 1 (CRMP1), a tumor suppressor, was a direct downstream target of miR (show MLXIP Proteins)-187.

  4. miR200a-3p promotes the proliferation of human esophageal cancer cells by post-transcriptionally regulating CRMP1.

  5. CRMP1 interacted with Spy1 (show SPDYA Proteins) which would disturb the association of CRMP1 with actin and was involved in the collapse of growth cones induced by Sema3A (show SEMA3A Proteins) and regeneration after sciatic nerve crush.

  6. These results demonstrate an important role for CRMP-1 in Listeria actin comet tail formation and open the possibility that CRMP-1 controls cell motility by modulating Arp2 (show ACTR2 Proteins)/3 activation.

  7. Human CRMP-1 comprises a tetrameric assembly.

  8. Results show that expression of CRMP1 is downregulated in medulloblastoma (MB) tumors. its overexpression inhibits proliferation, migration and invasion of cells suggesting that CRMP1 is implicated in MB pathogenesis.

  9. Aberrant upregulation of CRMP-1 expression may link to the mechanism of developing early-onset preeclampsia.

  10. CRMP1 targets aggregation-prone, N-terminal HTT (show HTT Proteins) fragments and suppresses their spontaneous self-assembly.

Mouse (Murine) Collapsin Response Mediator Protein 1 (CRMP1) interaction partners

  1. Results indicate that CRMP1 and CRMP4 (show DPYSL3 Proteins) regulate proper orientation of the basal dendrites of layer V neurons in the cerebral cortex during development.

  2. this paper shows that Nav1.7 (show SCN9A Proteins), by coupling with CRMP1, mediates the axonal retrograde signaling of Sema3A (show SEMA3A Proteins) in axonal guidance

  3. We generated CRMP2 (show DPYSL2 Proteins) gene-deficient (crmp2 (show DPYSL2 Proteins)(-/-) ) mice. The crmp2 (show DPYSL2 Proteins)(-/-) mice showed irregular development of dendritic spines in cortical neurons. The level of CRMP1 was increased in crmp2 (show DPYSL2 Proteins)(-/-) , but the level of CRMP2 (show DPYSL2 Proteins) was not altered in crmp1(-/-).The phenotypic defects had no genetic interaction between crmp1 and crmp2 (show DPYSL2 Proteins).

  4. LCRMP (show DPYSL3 Proteins)-1 and CRMP-1 have opposing functions in regulating cancer cell invasion and metastasis

  5. Data demonstrate that CRMP1 tyrosine 504 is a primary target of the Src (show SRC Proteins) family of tyrosine kinases (SFKs), specifically Fyn (show FYN Proteins).

  6. Data link the reduction in PMCA2 (show ATP2B2 Proteins) expression with perturbations in CRMP1 expression and death of spinal cord neurons, representing an additional mechanism underlying AMPA (show GRIA3 Proteins)/kainate receptor-mediated excitotoxicity with relevance to neurodegeneration in EAE.

  7. The structural bases for Crmp1 function in plexin-dependent sempahorin3A signaling were studied.

  8. In the olfactory bulb, CRMP1, CRMP2 (show DPYSL2 Proteins) and CRMP5 (show DPYSL5 Proteins) are abundant in neuronal progenitors of the subependymal layer and in differentiating interneurons.

  9. Mice lacking Crmp1 showed a decrease in the number of granule cells migrating out of explants of developing cerebellum.

  10. Collapsin response mediator protein 1 (CRMP1)regulates neuronal migration by mediating Reelin (show RELN Proteins) signaling.

Zebrafish Collapsin Response Mediator Protein 1 (CRMP1) interaction partners

  1. Crmp1 is expressed in numerous sites in the developing nervous system

Cow (Bovine) Collapsin Response Mediator Protein 1 (CRMP1) interaction partners

  1. These results demonstrate an important role for CRMP-1 in Listeria actin comet tail formation and open the possibility that CRMP-1 controls cell motility by modulating Arp2 (show ACTR2 Proteins)/3 activation.

CRMP1 Protein Profile

Protein Summary

This gene encodes a member of a family of cytosolic phosphoproteins expressed exclusively in the nervous system. The encoded protein is thought to be a part of the semaphorin signal transduction pathway implicated in semaphorin-induced growth cone collapse during neural development. Alternative splicing results in multiple transcript variants.

Gene names and symbols associated with CRMP1

  • collapsin response mediator protein 1 (CRMP1)
  • collapsin response mediator protein 1 (crmp1)
  • cysteine repeat modular protein 1, putative (PfCRMP1)
  • collapsin response mediator protein 1 (Crmp1)
  • CRMP-1 protein
  • CRMP 1 protein
  • crmp1 protein
  • CRMP1B protein
  • Dpysl1 protein
  • DRP-1 protein
  • DRP1 protein
  • MGC145930 protein
  • PCRMP-1 protein
  • PCRMP1 protein
  • PCRMP 1 protein
  • PfCRMP-1 protein
  • ULIP-3 protein
  • Ulip3 protein

Protein level used designations for CRMP1

collapsin response mediator protein 1 , cysteine repeat modular protein 1, putative , dihydropyrimidinase related protein-1 , dihydropyrimidinase-like 1 , dihydropyrimidinase-related protein 1 , unc-33-like phosphoprotein 3 , collapsin response mediator protein-1B , CRMP-1 , DRP-1

GENE ID SPECIES
100070014 Equus caballus
711349 Macaca mulatta
750614 Pan troglodytes
779767 Xenopus (Silurana) tropicalis
100350067 Oryctolagus cuniculus
100562361 Anolis carolinensis
813390 Plasmodium falciparum 3D7
1400 Homo sapiens
12933 Mus musculus
553756 Danio rerio
734422 Xenopus laevis
395156 Gallus gallus
479097 Canis lupus familiaris
504250 Bos taurus
25415 Rattus norvegicus
100520574 Sus scrofa
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