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The protein encoded by CSF1 is a cytokine that controls the production, differentiation, and function of macrophages. Additionally we are shipping CSF1 Antibodies (194) and CSF1 Kits (65) and many more products for this protein.
Showing 10 out of 82 products:
Human CSF1 Protein expressed in Escherichia coli (E. coli) - ABIN413611
Del Galdo, Wermuth, Addya, Fortina, Jimenez et al.: NF?B activation and stimulation of chemokine production in normal human macrophages by the gadolinium-based magnetic resonance contrast agent Omniscan: possible role in the pathogenesis of ... in Annals of the rheumatic diseases 2010
the high level of colony-stimulating factor 1 expression during bovine pregnancy in uteroplacental tissues is consistent with its proposed role in placental physiology
results suggest that leukemia inhibitory factor (show LIF Proteins) and macrophage-colony stimulating factor (show CSF2 Proteins) are produced in the endometrium and may play different roles in early and mid-pregnancy
These results indicate that BARF1 blockade of CSF-1 signaling is an important immune evasion strategy for efficient acute EBV infection and a significant determinant for virus setpoint during persistent EBV infection.
the complete sequencing of M-CSF (show CSF1R Proteins) genes, gene organizaztion,splice varaiants, gene expression, and M-CSF (show CSF1R Proteins) role in the immune system
Nucleolin (show NCL Proteins) both forms an mRNP complex with the eIF4G (show EIF4G1 Proteins) and CSF-1 mRNA, and is co-localized with the eIF4G (show EIF4G1 Proteins) in the cytoplasm further supporting nucleolin's role in translational regulation.
study, therefore, provided insights into the sequence-structure-function relationships of the M-CSF/c-FMS (show CSF1R Proteins) interaction and of ligand/receptor tyrosine kinase (show RET Proteins) interactions in general.
Therefore, our findings indicate that CSF1 signaling is oncogenic during gliomagenesis through a mechanism distinct from modulating glioma-associated microglia/macrophage polarization status
High CSF1 expression is associated with breast cancer.
M-CSF has been shown to be comparable to CA15-3 and VEGF, specificity, and AUC values only in stages III and IV of BC.
M-CSF macrophage conversion into foam cells reduces their proinflammatory responses to classical M1-polarizing activation
This can be achieved by either blocking the EGF (show EGF Proteins) or CSF-1 receptors or supressing the EGF (show EGF Proteins) or CSF-1 signal.
findings demonstrated that M-CSF binds to IL-34 (show IL34 Proteins); molecular docking studies predicted the formation of a heteromeric M-CSF/IL-34 (show IL34 Proteins) cytokine
RGC-32 (show C13orf15 Proteins) expression on M2-polarized and tumor-associated macrophages is M-CSF-dependent and enhanced by tumor-derived IL-4 (show IL4 Proteins).
Data show crystal structures of CSF1-CSF1R (show CSF1R Proteins) ternary complexes, and propose a mechanism for their cooperative action that relies on the adoption by dimeric CSF-1 of an active conformational state and homotypic receptor interactions.
NMB or NMBR silencing inhibited M-CSF (show CSF1R Proteins)/c-Fms (show CSF1R Proteins)-mediated downstream signaling pathways like activation of ERK (show EPHB2 Proteins) and Akt (show AKT1 Proteins) and induction of D-type cyclins, cyclin D1 (show CCND1 Proteins) and D2.
address which CSF-1-activated pathways are involved in transmitting the lineage-instructive signal in primary bone marrow-derived GM progenitors.
study concludes that M-CSF (show CSF1R Proteins) is critical to host defenses against bacterial pneumonia by mediating survival and antimicrobial functions of mononuclear phagocytes in the lungs and liver.
study, therefore, provided insights into the sequence-structure-function relationships of the M-CSF (show CSF1R Proteins)/c-FMS (show CSF1R Proteins) interaction and of ligand/receptor tyrosine kinase (show ERBB3 Proteins) interactions in general.
study shows that PLCgamma1 (show PLCG1 Proteins) controls osteoclast numbers via a CSF-1-dependent DAG/beta-catenin (show CTNNB1 Proteins)/cyclinD1 pathway.
study concludes that Langerhans cells require IL-34 (show IL34 Proteins) when residing in fully differentiated and anatomically intact skin epidermis, but rely on neutrophil-derived CSF1 during inflamma
Proteomic Analysis Reveals Distinct Metabolic Differences Between Granulocyte-Macrophage Colony Stimulating Factor (GM-CSF (show CSF2 Proteins)) and Macrophage Colony Stimulating Factor (show CSF2 Proteins) (M-CSF (show CSF1R Proteins)) Grown Macrophages Derived from Murine Bone Marrow Cells
Hematopoietic cells can be induced by M-CSF (show CSF1R Proteins) to dedifferentiate to multipotent stem cells.
M-CSF (show CSF1R Proteins) promotes macrophagic over granulocytic differentiation by inducing ERK (show EPHB2 Proteins) activation but also PKCd (show PKCd Proteins) expression, which in turn, down-regulates Fli-1 (show FLI1 Proteins) expression and prevents granulocytic differentiation.
The protein encoded by this gene is a cytokine that controls the production, differentiation, and function of macrophages. The active form of the protein is found extracellularly as a disulfide-linked homodimer, and is thought to be produced by proteolytic cleavage of membrane-bound precursors. The encoded protein may be involved in development of the placenta. Alternate splicing results in multiple transcript variants.
macrophage colony-stimulating factor 1
, colony stimulating factor 1 (macrophage)
, macrophage colony-stimulating factor 1-like
, colony-stimulating factor 1