Colony Stimulating Factor 3 Receptor (Granulocyte) Proteins (CSF3R)

The protein encoded by CSF3R is the receptor for colony stimulating factor 3, a cytokine that controls the production, differentiation, and function of granulocytes. Additionally we are shipping CSF3R Antibodies (210) and CSF3R Kits (41) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
CSF3R 298518  
CSF3R 1441 Q99062
CSF3R 12986 P40223
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Top CSF3R Proteins at antibodies-online.com

Showing 10 out of 26 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Mouse His tag 100 μg Log in to see 15 to 18 Days
$672.00
Details
HOST_Escherichia coli (E. coli) Rat His tag 100 μg Log in to see 15 to 18 Days
$714.00
Details
HOST_Human Cells Human Fc Tag 100 μg Log in to see 20 to 21 Days
$382.80
Details
HOST_HEK-293 Cells Human His tag 100 μg Log in to see 2 to 3 Days
$275.00
Details
HOST_Escherichia coli (E. coli) Human GST tag Colony Stimulating Factor 3 Receptor (Granulocyte) (CSF3R) (AA 25-620) protein (GST tag) 50 μg Log in to see 13 to 16 Days
$242.00
Details
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 50 Days
$5,442.50
Details
Insect Cells Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 50 Days
$5,442.50
Details
HOST_HEK-293 Cells Human His tag 100 μg Log in to see 2 to 3 Days
$615.00
Details
HOST_HEK-293 Human His tag   0.1 mg Log in to see 2 to 3 Days
$515.63
Details
HOST_Escherichia coli (E. coli) Human His tag   100 μg Log in to see 15 to 18 Days
$560.00
Details

CSF3R Proteins by Origin and Source

Origin Expressed in Conjugate
Rat (Rattus)

Human , , , , ,
, , , ,
Mouse (Murine) ,
,

Top referenced CSF3R Proteins

  1. Human CSF3R Protein expressed in Human Cells - ABIN2002378 : Germeshausen, Ballmaier, Welte: Incidence of CSF3R mutations in severe congenital neutropenia and relevance for leukemogenesis: Results of a long-term survey. in Blood 2006 (PubMed)
    Show all 5 Pubmed References

More Proteins for Colony Stimulating Factor 3 Receptor (Granulocyte) (CSF3R) Interaction Partners

Human Colony Stimulating Factor 3 Receptor (Granulocyte) (CSF3R) interaction partners

  1. a central role of enhanced Mapk (show MAPK1 Proteins) signaling in CSF3R-induced leukemia.

  2. CSF3R T618I mutation is associated with Chronic neutrophilic leukemia.

  3. biallelic CSF3R mutations were identified In the group of congenital neutropenia patients; CSF3R mutant clones are highly dynamic and may disappear and reappear during continuous granulocyte colony-stimulating factor (G-CSF (show CSF3 Proteins)) therapy. The time between the first detection of CSF3R mutations and overt leukemia is highly variable

  4. Co-occurrence of mutations in CSF3R and CEBPA (show CEBPA Proteins) in a well-defined AML (show RUNX1 Proteins) subset, which uniformly responds to JAK (show JAK3 Proteins) inhibitors; this paves the way to personalized clinical trials for this disease.

  5. The quantitative methods used in this study have shown non-altered expression levels of different microglial markers (Iba-1 (show AIF1 Proteins), Cd11b (show ITGAM Proteins) and CD68 (show CD68 Proteins)), together with increased expression of IL6 (show IL6 Proteins), IL10RA (show IL10RA Proteins), colony stimulating factor (show CSF2 Proteins) 3 receptor and toll-like receptor 7 (show TLR7 Proteins) in the thalamus in FFI, which explains the seemingly contradictory results of the previous studies.

  6. This study proposes that acquisition of CSF3R mutations may represent a mechanism by which myeloid precursor cells carrying the ELANE (show ELANE Proteins) mutations evade the proapoptotic activity of the Neutrophil Elastase (show ELANE Proteins) mutants in SCN (show SRI Proteins) patients.

  7. CSF3R expression is significantly upregulated in human masticatory mucosa during wound healing

  8. Results indicate that granulocyte-colony stimulating factor receptor, tissue factor, and vascular endothelial growth factor receptor bound vascular endothelial growth factor expression as well as their co-expression might influence breast cancer biology.

  9. The Colony-Stimulating Factor (show CSF2 Proteins) 3 Receptor T640N Mutation Is Oncogenic, Sensitive to JAK (show JAK3 Proteins) Inhibition, and Mimics T618I

  10. CSF3R mutations, mechanisms of mutations, and their contributions to the myeloid malignancies (Review)

Mouse (Murine) Colony Stimulating Factor 3 Receptor (Granulocyte) (CSF3R) interaction partners

  1. Anti-G-CSF receptor rapidly halted the progression of established disease in collagen Ab-induced arthritis in mice. Neutrophil accumulation in joints was inhibited, without rendering animals neutropenic, suggesting an effect of G-CSF receptor blockade on neutrophil homing to inflammatory sites.

  2. this study shows that dorsal root ganglion neurons cultured in G-CSF (show CSF3 Proteins) failed to respond to G-CSF (show CSF3 Proteins) in vitro, and Csf3r gene expression could not be detected in dorsal root ganglion neurons by single-cell RT-PCR

  3. Thr (show TRH Proteins)-615 and Thr (show TRH Proteins)-618 sites of membrane-proximal mutations are part of an O-linked glycosylation cluster. Mutation at these sites prevents O-glycosylation of CSF3R and increases receptor dimerization.

  4. Fbw7 (show FBXW7 Proteins) together with GSK3beta negatively regulates G-CSFR expression and its downstream signaling.

  5. G-CSFR signaling interacts with retinoic acid receptors in the regulation of myeloid differentiation

  6. Expression of truncated G-CSFR significantly shortens the latency of AML (show RUNX1 Proteins) in a G-CSF (show CSF3 Proteins)-dependent fashion and it is associated with a distinct AML (show RUNX1 Proteins) presentation characterized by higher blast counts and more severe myelosuppression.

  7. G-CSFR signals in bone marrow monocytic cells inhibit the production of trophic factors required for osteoblast lineage cell maintenance, ultimately leading to hematopoietic stem and progenitor cell mobilization.

  8. Signaling mechanisms coupled to tyrosines in the granulocyte colony-stimulating factor receptor orchestrate G-CSF (show CSF3 Proteins)-induced expansion of myeloid progenitor cells.

  9. murine granulocyte colony-stimulating factor receptor binds to a low molecular weight ligand

  10. Mice with truncated G-CSF (show CSF3 Proteins) receptors have neutropenia, susceptibility to infection, and bone marrow maturation arrest similar to severe congenital neutropenic humans, suggesting a role of receptor truncation mutations in SCN (show SRI Proteins) pathology.

Zebrafish Colony Stimulating Factor 3 Receptor (Granulocyte) (CSF3R) interaction partners

  1. GCSF (show CSF3 Proteins)/GCSFR is a conserved signaling system for facilitating the production of multiple myeloid cell lineages, as well as for early myeloid cell migration.

CSF3R Protein Profile

Protein Summary

The protein encoded by this gene is the receptor for colony stimulating factor 3, a cytokine that controls the production, differentiation, and function of granulocytes. The encoded protein, which is a member of the family of cytokine receptors, may also function in some cell surface adhesion or recognition processes. Alternatively spliced transcript variants have been described. Mutations in this gene are a cause of Kostmann syndrome, also known as severe congenital neutropenia.

Gene names and symbols associated with CSF3R

  • colony stimulating factor 3 receptor (granulocyte) (Csf3r)
  • colony stimulating factor 3 receptor (granulocyte) (CSF3R)
  • colony stimulating factor 3 receptor (granulocyte) (csf3r)
  • Cd114 protein
  • CSF3R protein
  • Csfgr protein
  • G-CSF-R protein
  • G-CSFR protein
  • GCSFR protein

Protein level used designations for CSF3R

granulocyte colony-stimulating factor receptor , colony stimulating factor 3 receptor (granulocyte) , granulocyte colony-stimulating factor receptor-like , CD114 antigen , G-CSF receptor , G-CSF-R , granulocyte stimulating factor receptor

GENE ID SPECIES
298518 Rattus norvegicus
281727 Bos taurus
446770 Xenopus laevis
456756 Pan troglodytes
607605 Canis lupus familiaris
100069253 Equus caballus
713485 Macaca mulatta
100433338 Pongo abelii
100464681 Ailuropoda melanoleuca
1441 Homo sapiens
12986 Mus musculus
419620 Gallus gallus
101118070 Ovis aries
100134935 Danio rerio
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