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Complement Component (3b/4b) Receptor 1-Like Proteins (CR1L)

CR1L encodes a membrane-bound inhibitor of complement activation, which contains several tandemly arranged short consensus repeats (SCRs) of approximately 60 amino acids. Additionally we are shipping Complement Component (3b/4b) Receptor 1-Like Antibodies (18) and Complement Component (3b/4b) Receptor 1-Like Kits (3) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
Rat CR1L CR1L 54243 Q63135
CR1L 1379 Q2VPA4
CR1L 12946 Q64735
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Top Complement Component (3b/4b) Receptor 1-Like Proteins at antibodies-online.com

Showing 3 out of 3 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 49 to 54 Days
$4,244.78
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details

CR1L Proteins by Origin and Source

Origin Expressed in Conjugate
Human

Mouse (Murine) ,
,

More Proteins for Complement Component (3b/4b) Receptor 1-Like (CR1L) Interaction Partners

Human Complement Component (3b/4b) Receptor 1-Like (CR1L) interaction partners

  1. CR1L transcript appears to be limited to hematopoietic and fetal lymphoid tissue.

Mouse (Murine) Complement Component (3b/4b) Receptor 1-Like (CR1L) interaction partners

  1. this study has provided direct evidence for a role of Crry in controlling spontaneous alternative pathway complement activation on renal tubular epithelial cells.

  2. HBx can up-regulate CD59 (show CD59 Proteins) and Crry expression in podocytes through activating the P38 (show CRK Proteins) pathway.

  3. Crry costimulation enhanced the in vitro expansion of natural Treg cells while maintaining their phenotypic and suppressive properties. Crry-expanded Treg cells decreasing antigen-dependent secretion of cytokines.

  4. Stmn2 (show STMN2 Proteins) and the chromosome 14 Rarb (show RARB Proteins) region, but not Cr1 (show TDGF1 Proteins) or Clu (show CLU Proteins) or Picalm (show PICALM Proteins), have roles in prion (show PRNP Proteins) disease.

  5. There is a significant reduction in the numbers of both neutrophils and macrophages in cardiac isografts isolated from mice treated with either complement receptor 2-Crry or CR2-factor H (show CFH Proteins).

  6. Crry is clearly present in the placentas from spontaneous abortions in mice.

  7. Crry is the only membrane-bound complement regulator expressed on the basolateral surface of murine renal tubular epithelial cells under in vitro culture conditions.

  8. Data show that a single-nucleotide polymorphism in the first short consensus repeat of Sle1c Crry introduced a novel N-linked glycosylation site likely responsible for structural alteration.

  9. mesangial cell Crry limits complement activation and subsequent neutrophil recruitment in the setting of local immune complex deposition.

  10. Long-term complement blockade with Crry, a C3 convertase inhibitor overexpressed in a transgenic mouse line, reduces renal disease and improves survival in lupus-prone MRL/lpr (show FAS Proteins) mice.

Complement Component (3b/4b) Receptor 1-Like (CR1L) Protein Profile

Protein Summary

This gene encodes a membrane-bound inhibitor of complement activation, which contains several tandemly arranged short consensus repeats (SCRs) of approximately 60 amino acids. The encoded protein may play a role in tumor immune surveillance, which is unrelated to complement inhibition. Three alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

Gene names and symbols associated with CR1L

  • complement component (3b/4b) receptor 1-like (CR1L)
  • complement component (3b/4b) receptor 1-like (Cr1l)
  • Cr1 protein
  • CREG protein
  • Crry protein
  • Mcp protein
  • mCRY protein

Protein level used designations for CR1L

complement component (3b/4b) receptor 1-like , complement regulatory GPI-anchor protein , 5I2 antigen , Complement receptor related protein , antigen 5I2 , complement component receptor 1-like protein , complement receptor type 1 , complement regulatory protein Crry , complement C4b-binding protein CR-1-like protein , complement receptor related protein , protein p65

GENE ID SPECIES
419853 Gallus gallus
450119 Pan troglodytes
54243 Rattus norvegicus
1379 Homo sapiens
12946 Mus musculus
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