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Complement Component (3d/Epstein Barr Virus) Receptor 2 Proteins (CR2)

CR2 encodes a membrane protein, which functions as a receptor for Epstein-Barr virus (EBV) binding on B and T lymphocytes. Additionally we are shipping Complement Component (3d/Epstein Barr Virus) Receptor 2 Antibodies (452) and Complement Component (3d/Epstein Barr Virus) Receptor 2 Kits (13) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
CR2 1380 P20023
CR2 289395  
CR2 12902  
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Top Complement Component (3d/Epstein Barr Virus) Receptor 2 Proteins at antibodies-online.com

Showing 8 out of 9 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Human Cells Human His tag 100 μg Log in to see 16 Days
$382.80
Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 69 to 74 Days
$9,050.32
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 39 to 44 Days
$9,248.02
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 39 to 44 Days
$9,248.02
Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 69 to 74 Days
$12,906.52
Details
HOST_HEK293 Human His tag   100 μg Log in to see 2 to 3 Days
$383.90
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   5 applications Log in to see 1 to 2 Days
$312.71
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

CR2 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , , , ,
,
Rat (Rattus)
Mouse (Murine) ,
,

Top referenced Complement Component (3d/Epstein Barr Virus) Receptor 2 Proteins

  1. Human CR2 Protein expressed in Human Cells - ABIN2003429 : Gregory, Barlow, McLay, Kaul, Swarbreck, Dunham, Scott, Howe, Woodfine, Spencer, Jones, Gillson, Searle, Zhou, Kokocinski, McDonald, Evans, Phillips, Atkinson, Cooper, Jones, Hall, Andrews, Lloyd et al.: The DNA sequence and biological annotation of human chromosome 1. ... in Nature 2006 (PubMed)
    Show all 5 references for ABIN2003429

More Proteins for Complement Component (3d/Epstein Barr Virus) Receptor 2 (CR2) Interaction Partners

Human Complement Component (3d/Epstein Barr Virus) Receptor 2 (CR2) interaction partners

  1. In mature B cells, CD21 transcription proceeds from a focused transcriptional start site regulated by a non-consensus TATA box, an initiator element and a downstream promoter element.

  2. Reduced expression of CD21 on CLL B-cells appears functionally relevant and was associated with poor clinical outcomes.

  3. These data suggest that rs1876453 in CR2 has long-range effects on gene regulation that decrease susceptibility to systemic lupus erythematosus.

  4. repression of the CR2/CD21 promoter can occur through one of the E-box motifs via recruitment of RP58 (show ZNF238 Proteins).

  5. found that the protective CR2 genotype is correlated with lower levels CR2 mRNA as well as differences in the ratio of the long and short CR2 isoforms

  6. The paradoxical enhancement of immune responses by C3d (show C3 Proteins) in the absence of CD21 is due to internalization and processing of C3d (show C3 Proteins) into peptides that activate autoreactive CD4 (show CD4 Proteins)(+) T-helper cells.

  7. THE COMBINATION OF EXPRESSION OF MARKERS CR1 AND CR2 (CD35/CD21) IN DIAGNOSTIC OF B-CELL LYMPHOPROLIFERATIVE DISEASES

  8. Higher C3d (show C3 Proteins)/C3 ratios were found for current smoker, higher age, age-related macular degeneration phenotype, and the two SNPs in the C3 gene, rs6795735 and rs2230199.

  9. Authors show that expression of the Epstein-Barr virus B-cell attachment receptor, CD21, in B cells that lack this receptor results in significant changes in gene expression, both before and rapidly following EBV-CD21 interaction.

  10. Our findings implicate CR2 as a susceptibility gene for nasopharyngeal carcinoma and suggest that enhanced CR2 expression may be involved in the oncogenesis and development of nasopharyngeal carcinoma.

Cow (Bovine) Complement Component (3d/Epstein Barr Virus) Receptor 2 (CR2) interaction partners

  1. Cattle express two major variants of the Cr2 gene representing homologues of murine CR1 and CR2, each of which is expressed in both a long and a short form.

Mouse (Murine) Complement Component (3d/Epstein Barr Virus) Receptor 2 (CR2) interaction partners

  1. These results demonstrate that local expression of Cr2 in the central nervous system is part of the axotomy reaction and is suggested to modulate subsequent complement mediated effects.

  2. This study demonistrated that receptors for complement C3 (show C3 Proteins) fragments (CR2/CR1) may represent a promising future approach for therapeutic immunomodulation after traumatic brain injury.

  3. Data suggest that the Cr2KO mouse thus provides a new model system for the analysis of Cr1 and Cr2 functions in the immune response of the mouse.

  4. Murine B cells predominantly express the Cr2 product from the Cr2 gene, whereas follicular dendritic cells (FDCs) almost exclusively express the Cr1 isoform generated from the Cr2 gene.

  5. immune system uses three different CR1 (show TDGF1 Proteins)/2-mediated effector functions to generate optimal antibody responses

  6. Absence of CD21/35 protects mice from chronic wasting disease.

  7. We conclude that Cr2 regulates hippocampal neurogenesis

  8. There is a significant reduction in the numbers of both neutrophils and macrophages in cardiac isografts isolated from mice treated with either complement receptor 2-Crry (show CR1L Proteins) or CR2-factor H (show CFH Proteins).

  9. Differential expression of CD21 identifies developmentally and functionally distinct subsets of human transitional B cells.

  10. functionally significant phenotype for the NZM2410 Cr2 allele and strongly support its role as a lupus susceptibility gene

Complement Component (3d/Epstein Barr Virus) Receptor 2 (CR2) Protein Profile

Protein Summary

This gene encodes a membrane protein, which functions as a receptor for Epstein-Barr virus (EBV) binding on B and T lymphocytes. Genetic variations in this gene are associated with susceptibility to systemic lupus erythematosus type 9 (SLEB9). Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with CR2

  • complement component (3d/Epstein Barr virus) receptor 2 (CR2)
  • complement component (3d/Epstein Barr virus) receptor 2 (Cr2)
  • complement receptor 2 (Cr2)
  • C3DR protein
  • Cd21 protein
  • CD35 protein
  • CR protein
  • Cr-1 protein
  • Cr-2 protein
  • Cr1 protein
  • CVID7 protein
  • SLEB9 protein

Protein level used designations for CR2

EBV receptor , complement C3d receptor , complement receptor type 2 , epstein-Barr virus receptor , complement component receptor 2 , complement receptor 1 long isoform , complement receptor 2 , complement receptor type 1 , expressed in B lymphocytes

GENE ID SPECIES
1380 Homo sapiens
407126 Bos taurus
289395 Rattus norvegicus
12902 Mus musculus
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