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anti-Complement Factor H-Related 5 (CFHR5) Antibodies

CFHR5 is a member of a small complement factor H (CFH) gene cluster on chromosome 1. Additionally we are shipping Complement Factor H-Related 5 Kits (14) and Complement Factor H-Related 5 Proteins (5) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
CFHR5 81494 Q9BXR6
CFHR5    
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Top anti-Complement Factor H-Related 5 Antibodies at antibodies-online.com

Showing 10 out of 67 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated WB WB Suggested Anti-CFHR5 AntibodyTitration: 1.0 µg/mL  Positive Control: THP-1 Whole Cell 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated FACS, IHC (p), WB CFHR5 Antibody (Center) (ABIN651876) western blot analysis in CEM,K562 cell line lysates (15 µg/lane). This demonstrates the CFHR5 antibody detected the CFHR5 protein (arrow). CFHR5 Antibody (Center) (ABIN651876) immunohistochemistry analysis in formalin fixed and paraffin embedded human hepatocarcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated WB Western Blot analysis of CFHR5 expression in transfected 293T cell line by CFHR5 MaxPab polyclonal antibody.Lane 1: CFHR5 transfected lysate(64.40 KDa).Lane 2: Non-transfected lysate. 100 μg Log in to see 9 Days
$418.57
Details
Human Mouse Un-conjugated IP, ELISA, WB   100 μg Log in to see 8 to 10 Days
$793.83
Details
Human Rabbit PE FACS, IHC, ELISA, WB   200 μL Log in to see 8 to 10 Days
$969.83
Details
Human Rabbit Un-conjugated IP, WB Immunoprecipitation of CFHR5 transfected lysate using anti-CFHR5 MaxPab rabbit polyclonal antibody and Protein A Magnetic Bead , and immunoblotted with CFHL5 purified MaxPab mouse polyclonal antibody (B01P) . Western Blot analysis of CFHR5 expression in transfected 293T cell line by CFHR5 MaxPab polyclonal antibody.Lane 1: CFHR5 transfected lysate(64.40 KDa).Lane 2: Non-transfected lysate. 100 μL Log in to see 9 Days
$418.57
Details
Human Rabbit Un-conjugated WB   50 μg Log in to see 8 to 10 Days
$551.83
Details
Human Rabbit Un-conjugated ELISA   200 μL Log in to see 8 to 10 Days
$713.17
Details
Human Mouse Un-conjugated WB Western Blot analysis of CFHR5 expression in transfected 293T cell line by CFHR5 MaxPab polyclonal antibody.Lane 1: CFHL5 transfected lysate(62.59 KDa).Lane 2: Non-transfected lysate. CFHR5 MaxPab polyclonal antibody. Western Blot analysis of CFHR5 expression in human kidney. 50 μg Log in to see 9 Days
$430.00
Details
Human Rabbit Un-conjugated IHC, ELISA, WB 400 μL Log in to see 6 Days
$457.14
Details

CFHR5 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Human ,
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Mouse (Murine)


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Top referenced anti-Complement Factor H-Related 5 Antibodies

  1. Human Polyclonal CFHR5 Primary Antibody for WB - ABIN529341 : Medjeral-Thomas, Malik, Patel, Toth, Cook, Tomson, Pickering: A novel CFHR5 fusion protein causes C3 glomerulopathy in a family without Cypriot ancestry. in Kidney international 2014 (PubMed)

More Antibodies against Complement Factor H-Related 5 Interaction Partners

Human Complement Factor H-Related 5 (CFHR5) interaction partners

  1. Next-generation sequencing of the CFH (show CFH Antibodies) region identified putatively functional variants (missense, splice site and indel) on the four common haplotypes. We found no expression of any of the five CFH (show CFH Antibodies)-related genes in the retina or RPE (show RPE Antibodies)/Choroid/Sclera, in contrast to the liver, which is the main source of the circulating proteins. [CFHR5]

  2. Studies indicate that complement factor H (show CFH Antibodies)-related proteins (FHR1 (show CFHR1 Antibodies)-5) may enhance complement activation, with important implications for the role of these proteins in disease.

  3. In this study, we identify pentraxin 3 (PTX3 (show PTX3 Antibodies)) as a novel ligand of CFHR5

  4. At least two distinct intronic breakpoints within the CFHR5 gene can cause the same mutant CFHR5 protein and C3 glomerulopathy.

  5. A hybrid CFHR2 (show CFHR2 Antibodies)-CFHR5 plasma protein, arising from a chromosomal deletion mutation stabilizes the C3 convertase and reduces factor H (show CFH Antibodies)-mediated convertase decay.

  6. Recent investigations in London and Cyprus culminated in the identification of another autosomal dominant condition that presents with microscopic haematuria because of heterozygous mutations in the CFHR5 gene--{review}

  7. A potentially pathogenic sequence variation was found in CFHR5 in the patients with atypical hemolytic uremic syndrome.

  8. CFHR5 nephropathy is discussed.

  9. Describe the clinical course, significant variable expressivity, and marked gender difference regarding the development of chronic renal failure in familial C3 glomerulopathy associated with CFHR5 mutations.

  10. evidence for an inherited renal disease, endemic in Cyprus, characterised by microscopic and synpharyngitic macroscopic haematuria, renal failure and C3 glomerulonephritis; affected individuals have an internal duplication within the gene for CFHR5

Complement Factor H-Related 5 (CFHR5) Antigen Profile

Protein Summary

This gene is a member of a small complement factor H (CFH) gene cluster on chromosome 1. Each member of this gene family contains multiple short consensus repeats (SCRs) typical of regulators of complement activation. The protein encoded by this gene has nine SCRs with the first two repeats having heparin binding properties, a region within repeats 5-7 having heparin binding and C reactive protein binding properties, and the C-terminal repeats being similar to a complement component 3 b (C3b) binding domain. This protein co-localizes with C3, binds C3b in a dose-dependent manner, and is recruited to tissues damaged by C-reactive protein. Allelic variations in this gene have been associated, but not causally linked, with two different forms of kidney disease: membranoproliferative glomerulonephritis type II (MPGNII) and hemolytic uraemic syndrome (HUS).

Gene names and symbols associated with CFHR5

  • complement factor H-related 5 (CFHR5) antibody
  • CFHL5 antibody
  • CFHR5D antibody
  • FHR-5 antibody
  • FHR5 antibody

Protein level used designations for CFHR5

complement factor H-related protein 5 , factor H-related protein 5

GENE ID SPECIES
81494 Homo sapiens
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