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Complexin 2 Proteins (CPLX2)

Proteins encoded by the complexin/synaphin gene family are cytosolic proteins that function in synaptic vesicle exocytosis. Additionally we are shipping Complexin 2 Antibodies (35) and Complexin 2 Kits (12) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
CPLX2 12890 P84086
CPLX2 116657 P84087
CPLX2 10814 Q6PUV4
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Top Complexin 2 Proteins at antibodies-online.com

Showing 10 out of 12 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag 100 μg Log in to see 16 Days
$437.80
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human His tag 100 μg Log in to see 11 to 13 Days
$668.80
Details
Yeast Cow His tag   1 mg Log in to see 56 to 66 Days
$2,280.67
Details
Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
$2,280.67
Details
HOST_Escherichia coli (E. coli) Mouse His tag 100 μg Log in to see 11 to 13 Days
$735.90
Details
HOST_Escherichia coli (E. coli) Mouse Un-conjugated   100 μg Log in to see 9 to 19 Days
$904.80
Details
HOST_Sf-9 Cells Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$460.85
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

CPLX2 Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine)

Rat (Rattus)

Human , ,

Top referenced Complexin 2 Proteins

  1. Human CPLX2 Protein expressed in Escherichia coli (E. coli) - ABIN2004894 : Falkowski, Thomas, Groblewski: Complexin 2 modulates vesicle-associated membrane protein (VAMP) 2-regulated zymogen granule exocytosis in pancreatic acini. in The Journal of biological chemistry 2010 (PubMed)

More Proteins for Complexin 2 (CPLX2) Interaction Partners

Mouse (Murine) Complexin 2 (CPLX2) interaction partners

  1. Complexin II is a central target molecule that links NADPH oxidase (show NOX1 Proteins)-derived reactive oxygen species to glutamate (show GRIN1 Proteins)-mediated neuronal excitotoxicity in ischemic stroke.

  2. CpxII attenuates fluctuations of the early fusion pore and slows its expansion.

  3. Cplx 1 (show CPLX1 Proteins) and 2 play a role in facilitating vesicle priming, and also lead to the new hypothesis that Cplxs may synchronize vesicle release by promoting coupling between secretory vesicles and calcium channels.

  4. Cplx2 knockout mice exhibit hyperlocomotion following neonatal isolation stress.

  5. Several months after lesion, Cplx2 null mutants showed reduced pre-pulse inhibition, deficit of spatial learning and loss of inhibition after MK-801 challenge.

  6. Complexin 2 knockout mice show significant abnormalities in cognitive function and synaptic plasticity.

  7. We found an early and progressive decrease of CPLXII expression in R6/2 mice brains. In contrast, no changes in SNARE (show VTI1B Proteins) expression were seen in R6/2 brains compared with wild type brain.

  8. stabilization of SNARE (show VTI1B Proteins) interactions by complexin is an essential aspect of the regulated trafficking events that increase apical membrane epithelial sodium channel density either by constitutive or regulated trafficking pathways

  9. CPXs regulate the size of the primed vesicle pools and have a positive role in Ca(2 (show CA2 Proteins)+)-triggered exocytosis in chromaffin cells

Human Complexin 2 (CPLX2) interaction partners

  1. Then results indicated that CPLX2 may be involved in the etiology of schizophrenia and one of its potential biological mechanisms by studying the effects of CPLX2 risk variants on working memory load-dependent neural activity in a frontoparietal network.

  2. These results suggested that CPLX2 participated in synaptic taste transduction.

  3. CPLX2 rs1366116*T variant represents a risk factor of schizophrenia, and , at the same time, CPLX2 rs3892909*T variant is protective against schizophrenia (study performed in Armenians).

  4. in huntingtin (show HTT Proteins) mutation, the decline in neurotransmitter release is a direct consequence of complexin II depletion

  5. In schizophrenia, complexin II was reduced in dorsolateral prefrontal cortex and superior temporal cortex. The impairment of synaptic transmission may contribute to the dysfunction of cortical neural circuits that characterises the disorder.

  6. CX2 (show IL17C Proteins) level increased between the fetal and the 6-10 years groups and then plateaued

Complexin 2 (CPLX2) Protein Profile

Protein Summary

Proteins encoded by the complexin/synaphin gene family are cytosolic proteins that function in synaptic vesicle exocytosis. These proteins bind syntaxin, part of the SNAP receptor. The protein product of this gene binds to the SNAP receptor complex and disrupts it, allowing transmitter release. Two transcript variants encoding the same protein have been found for this gene.

Gene names and symbols associated with Complexin 2 Proteins (CPLX2)

  • complexin 2 (cplx2)
  • complexin 2 (CPLX2)
  • complexin 2 (Cplx2)
  • 921-L protein
  • AI413745 protein
  • AW492120 protein
  • CPLX1 protein
  • CPX-2 protein
  • CPX2 protein
  • Hfb1 protein
  • MGC68923 protein
  • MGC79539 protein

Protein level used designations for Complexin 2 Proteins (CPLX2)

complexin 2 , complexin-2 , CPX II , complexin II , synaphin-1 , synaphin 1 , complexin 1

GENE ID SPECIES
379690 Xenopus laevis
489107 Canis lupus familiaris
493222 Xenopus (Silurana) tropicalis
556701 Danio rerio
750228 Pan troglodytes
12890 Mus musculus
116657 Rattus norvegicus
10814 Homo sapiens
281711 Bos taurus
427286 Gallus gallus
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