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COG6 encodes a subunit of the conserved oligomeric Golgi complex that is required for maintaining normal structure and activity of the Golgi apparatus. Additionally we are shipping COG6 Proteins (4) and many more products for this protein.
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Human Monoclonal COG6 Primary Antibody for ELISA, WB - ABIN566126
Liu, Helms, Liao, Zaba, Duan, Gardner, Wise, Miner, Malloy, Pullinger, Kane, Saccone, Worthington, Bruce, Kwok, Menter, Krueger, Barton, Saccone, Bowcock: A genome-wide association study of psoriasis and psoriatic arthritis identifies new disease loci. in PLoS genetics 2008
study presents 7 additional patients with 4 novel COG6 mutations; genotype-phenotype correlation can be discerned ranging from deep intronic mutations found in Shaheen syndrome as the mildest form to loss-of-function mutations leading to early lethal congenital disorders of glycosylation phenotypes
The aim of this study was to investigate whether the HCP5, TNIP1 (show TNIP1 Antibodies), TNFAIP3 (show TNFAIP3 Antibodies), SPATA2 (show SPATA2 Antibodies) and COG6 genes were genetic risk factors for psoriasis in Chinese population.
Our findings implicate COG6 rs9548934C-->T genotypes and circulating miRNA-1 phenotype in modulating the occurrence and major adverse cardiovascular events of coronary artery disease.
Targeted silencing of components of lobe B of the COG (show TG Antibodies) complex, namely COG5 (show COG5 Antibodies), COG6, COG7 (show COG7 Antibodies) and COG8 (show COG8 Antibodies), inhibited HIV-1 replication
data implicate COG6 in the pathogenesis of a novel hypohidrotic disorder in humans that is distinct from congenital disorders of glycosylation.
COG6 interaction with SNARE (show NAPA Antibodies) proteins via universal SNARE (show NAPA Antibodies)-binding motif of COG6 is important for Golgi complex intergrity.
COG6 rs9548934C-->T polymorphism is associated with lower risk of premature coronary artery disease, especially in female subjects and subjects with lower serum lipid levels.
COG (show TG Antibodies) directly and positively regulates endosome-to-TGN (show TG Antibodies) retrograde transport by specific and direct interaction with the t-SNARE (show NAPA Antibodies) Stx6 (show STX6 Antibodies) via its Cog6 subunit.
This paper reports a new congenital disorder caused by mutations in the human COG8 (show COG8 Antibodies) gene and describes the affect this mutation has on the other COG (show TG Antibodies) components.
This gene encodes a subunit of the conserved oligomeric Golgi complex that is required for maintaining normal structure and activity of the Golgi apparatus. The encoded protein is organized with conserved oligomeric Golgi complex components 5, 7 and 8 into a sub-complex referred to as lobe B. Alternative splicing results in multiple transcript variants.
component of oligomeric golgi complex 6
, Conserved oligomeric Golgi complex component 6
, COG complex subunit 6
, complexed with Dor1p 2
, conserved oligomeric Golgi complex protein 6
, conserved oligomeric Golgi complex subunit 6
, potential intra-Golgi transport complex subunit 6