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COG6 encodes a subunit of the conserved oligomeric Golgi complex that is required for maintaining normal structure and activity of the Golgi apparatus. Additionally we are shipping COG6 Antibodies (32) and many more products for this protein.
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COG6 is a novel shared risk locus for rheumatoid arthritis and systemic lupus erythematosus.
study presents 7 additional patients with 4 novel COG6 mutations; genotype-phenotype correlation can be discerned ranging from deep intronic mutations found in Shaheen syndrome as the mildest form to loss-of-function mutations leading to early lethal congenital disorders of glycosylation phenotypes
The aim of this study was to investigate whether the HCP5, TNIP1 (show TNIP1 Proteins), TNFAIP3 (show TNFAIP3 Proteins), SPATA2 (show SPATA2 Proteins) and COG6 genes were genetic risk factors for psoriasis in Chinese population.
Our findings implicate COG6 rs9548934C-->T genotypes and circulating miRNA-1 phenotype in modulating the occurrence and major adverse cardiovascular events of coronary artery disease.
Targeted silencing of components of lobe B of the COG (show TG Proteins) complex, namely COG5 (show COG5 Proteins), COG6, COG7 (show COG7 Proteins) and COG8 (show COG8 Proteins), inhibited HIV-1 replication
data implicate COG6 in the pathogenesis of a novel hypohidrotic disorder in humans that is distinct from congenital disorders of glycosylation.
COG6 interaction with SNARE (show NAPA Proteins) proteins via universal SNARE (show NAPA Proteins)-binding motif of COG6 is important for Golgi complex intergrity.
COG6 rs9548934C-->T polymorphism is associated with lower risk of premature coronary artery disease, especially in female subjects and subjects with lower serum lipid levels.
COG (show TG Proteins) directly and positively regulates endosome-to-TGN (show TG Proteins) retrograde transport by specific and direct interaction with the t-SNARE (show NAPA Proteins) Stx6 (show STX6 Proteins) via its Cog6 subunit.
This paper reports a new congenital disorder caused by mutations in the human COG8 (show COG8 Proteins) gene and describes the affect this mutation has on the other COG (show TG Proteins) components.
This gene encodes a subunit of the conserved oligomeric Golgi complex that is required for maintaining normal structure and activity of the Golgi apparatus. The encoded protein is organized with conserved oligomeric Golgi complex components 5, 7 and 8 into a sub-complex referred to as lobe B. Alternative splicing results in multiple transcript variants.
component of oligomeric golgi complex 6
, Conserved oligomeric Golgi complex component 6
, COG complex subunit 6
, complexed with Dor1p 2
, conserved oligomeric Golgi complex protein 6
, conserved oligomeric Golgi complex subunit 6
, potential intra-Golgi transport complex subunit 6