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anti-Contactin Associated Protein-Like 2 (CNTNAP2) Antibodies

CNTNAP2 encodes a member of the neurexin family which functions in the vertebrate nervous system as cell adhesion molecules and receptors. Additionally we are shipping CNTNAP2 Kits (10) and CNTNAP2 Proteins (6) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
CNTNAP2 362355  
CNTNAP2 26047 Q9UHC6
CNTNAP2 66797 Q9CPW0
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Top anti-CNTNAP2 Antibodies at antibodies-online.com

Showing 10 out of 53 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated EIA, WB Western blot analysis of CNTNAP2 Antibody (Center) in CEM cell line lysates (35ug/lane). CNTNAP2 (arrow) was detected using the purified Pab. 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated   100 μg Log in to see 3 to 4 Days
$257.40
Details
Human Rabbit Un-conjugated IHC (p), WB Western blot analysis of CNTNAP2 Antibody (Center) (ABIN652646) in CEM cell line lysates (35 µg/lane). CNTNAP2 (arrow) was detected using the purified polyclonal antibody. Formalin-fixed and paraffin-embedded mouse brain tissue reacted with CNTNAP2 Antibody (Center), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated IF (p), IHC (p), WB Formalin-fixed and paraffin embedded mouse brain labeled with Anti Caspr2 Polyclonal Antibody, Unconjugated (ABIN1386423) at 1:200 followed by conjugation to the secondary antibody and DAB staining 100 μL Log in to see 3 to 7 Days
$269.50
Details
Mouse Rabbit Un-conjugated ELISA   100 μg Log in to see 16 Days
$163.90
Details
Human Rabbit Alexa Fluor 594 IF (p)   100 μL Log in to see 14 to 21 Days
$357.50
Details
Human Mouse Un-conjugated IF, IHC, WB   100 μg Log in to see 8 to 10 Days
$625.17
Details
Human Rabbit Alkaline Phosphatase (AP) ELISA, WB   200 μL Log in to see 8 to 10 Days
$969.83
Details
Human Rabbit Alexa Fluor 555 IF (p)   100 μL Log in to see 14 to 21 Days
$357.50
Details
Human Rabbit Alexa Fluor 647 IF (p)   100 μL Log in to see 14 to 21 Days
$357.50
Details

CNTNAP2 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Rat (Rattus)
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Top referenced anti-CNTNAP2 Antibodies

  1. Human Polyclonal CNTNAP2 Primary Antibody for EIA, WB - ABIN453579 : Denisenko-Nehrbass, Oguievetskaia, Goutebroze, Galvez, Yamakawa, Ohara, Carnaud, Girault: Protein 4.1B associates with both Caspr/paranodin and Caspr2 at paranodes and juxtaparanodes of myelinated fibres. in The European journal of neuroscience 2003 (PubMed)
    Show all 2 references for ABIN453579

  2. Mouse (Murine) Polyclonal CNTNAP2 Primary Antibody for ELISA - ABIN2001277 : Verkerk, Mathews, Joosse, Eussen, Heutink, Oostra: CNTNAP2 is disrupted in a family with Gilles de la Tourette syndrome and obsessive compulsive disorder. in Genomics 2003 (PubMed)

  3. Human Polyclonal CNTNAP2 Primary Antibody for - ABIN2017587 : Chen, Koopmans, Gordon, Paliukhovich, Klaassen, van der Schors, Peles, Verhage, Smit, Li: Interaction proteomics of canonical Caspr2 (CNTNAP2) reveals the presence of two Caspr2 isoforms with overlapping interactomes. in Biochimica et biophysica acta 2015 (PubMed)

More Antibodies against CNTNAP2 Interaction Partners

Human Contactin Associated Protein-Like 2 (CNTNAP2) interaction partners

  1. CNTNAP2 is transcriptionally regulated by FOXP2 (show FOXP2 Antibodies).

  2. Structurally, CASPR2 is highly glycosylated and has an overall compact architecture. CASPR2 associates with micromolar affinity with CNTN1 (show CNTN1 Antibodies) but, under the same conditions, it does not interact with any of the other members of the contactin family.

  3. Results indicate that the CNTNAP2 gene may confer vulnerability to speech sound disorder

  4. The study of zebrafish mutants of the ASD (show ARSD Antibodies) risk gene, CNTNAP2, and its differential responses to psychoactive agents reveals the strength of this approach to identify molecular mechanisms

  5. Deletions within CNTNAP2 were found in two children with CAS (show CSE1L Antibodies) but not in any of the children with SLI (show SHC2 Antibodies). These findings suggest that genetic variation within CNTNAP2 may be related to speech production deficits.

  6. A genetic and functional characterization study of the CNTNAP2 promoter in autism spectrum disorders

  7. A new male-specific association with aging is reported for a CNV in the CNTNAP2 gene. esv11910 ins (show INS Antibodies) allele was inversely associated with healthy aging in men.

  8. We find no evidence for statistically significant association of rare heterozygous mutations in any of the CNTN (show CNTN1 Antibodies) or CNTNAP (show CNTNAP1 Antibodies) genes, including CNTNAP2, placing marked limits on the scale of their plausible contribution to risk.

  9. Encompassing CNTNAP2 exon 3.

  10. Study provides an improved estimate of the contribution of mutations in GNPTAB (show GNPTAB Antibodies), GNPTG (show GNPTG Antibodies) and NAGPA (show NAGPA Antibodies) to persistent stuttering, and suggests that variants in FOXP2 (show FOXP2 Antibodies) and CNTNAP2 are not involved in the genesis of familial persistent stuttering

Mouse (Murine) Contactin Associated Protein-Like 2 (CNTNAP2) interaction partners

  1. Olfaction-based behavioral tests revealed that mice lacking Caspr2 exhibit abnormal response to sensory stimuli and lack preference for novel odors.

  2. Mice with the Cntnap2 genetic mutation showed a dissociation of auditory-processing abilities

  3. Study reports behavioral characterization of mouse models of autism with null mutation in Cntnap2 gene. It shows hyperactivity, mild gait phenotype and reduced vocalizations among others.

  4. new dendritic spines in mice lacking CNTNAP2 were formed at normal rates, but failed to stabilize. Notably, rates of spine elimination were unaltered, suggesting a specific role for CNTNAP2 in stabilizing new synaptic circuitry

  5. Cntnap2 deletion selectively impairs perisomatic hippocampal inhibition while sparing excitation provide additional support for synaptic dysfunction as a common mechanism underlying autism spectrum disorders

  6. The CASPR2/MUPP1 (show MPDZ Antibodies) receptor complex co-localized with GPR37 (show GPR37 Antibodies) in hippocampal neurons.

  7. Interaction proteomics revealed the interactors of Caspr2, including CNTN2 (show CNTN2 Antibodies), KCNAs, members of the ADAM family (ADAM22 (show ADAM22 Antibodies), ADAM23 (show Adam23 Antibodies) and ADAM11 (show ADAM11 Antibodies)), members of LGI family and MAGUKs (DLGs and MPPs (show MPHOSPH6 Antibodies)).

  8. CNTNAP2 has a role in the correct trafficking of GluA1 (show GRIA1 Antibodies) AMPA (show GRIA3 Antibodies)-type glutamate (show GRIN1 Antibodies) receptors

  9. Caspr2 is required for paranodal clustering of Kv1 (show KCNA5 Antibodies) channels in the absence of Caspr (show CNTNAP1 Antibodies). Absence of both Caspr (show CNTNAP1 Antibodies) and Caspr2 results in the widening of the nodes of Ranvier.

  10. two novel genes, Cntnap2 and Tag1 (show CNTN2 Antibodies), are implicated in the regulation of diet-induced obesity.

CNTNAP2 Antigen Profile

Protein Summary

This gene encodes a member of the neurexin family which functions in the vertebrate nervous system as cell adhesion molecules and receptors. This protein, like other neurexin proteins, contains epidermal growth factor repeats and laminin G domains. In addition, it includes an F5/8 type C domain, discoidin/neuropilin- and fibrinogen-like domains, thrombospondin N-terminal-like domains and a putative PDZ binding site. This protein is localized at the juxtaparanodes of myelinated axons, and mediates interactions between neurons and glia during nervous system development and is also involved in localization of potassium channels within differentiating axons. This gene encompasses almost 1.5% of chromosome 7 and is one of the largest genes in the human genome. It is directly bound and regulated by forkhead box protein P2 (FOXP2), a transcription factor related to speech and language development. This gene has been implicated in multiple neurodevelopmental disorders, including Gilles de la Tourette syndrome, schizophrenia, epilepsy, autism, ADHD and mental retardation.

Gene names and symbols associated with CNTNAP2

  • contactin associated protein-like 2 (CNTNAP2) antibody
  • contactin associated protein-like 2 (cntnap2) antibody
  • contactin associated protein-like 2 (Cntnap2) antibody
  • 5430425M22Rik antibody
  • AUTS15 antibody
  • CASPR antibody
  • Caspr2 antibody
  • CDFE antibody
  • MGC145769 antibody
  • MGC147944 antibody
  • MGC147981 antibody
  • mKIAA0868 antibody
  • NRXN4 antibody
  • PTHSL1 antibody

Protein level used designations for CNTNAP2

cell recognition molecule Caspr2 , contactin associated protein-like 2 , novel protein similar to H.sapiens contactin associated protein , contactin associated protein 2 , contactin-associated protein-like 2 , contactin-associated protein-like 2-like , homolog of Drosophila neurexin IV

GENE ID SPECIES
463819 Pan troglodytes
516395 Bos taurus
563345 Danio rerio
574172 Macaca mulatta
780189 Xenopus (Silurana) tropicalis
100174321 Pongo abelii
362355 Rattus norvegicus
100013863 Monodelphis domestica
100060296 Equus caballus
100073864 Ornithorhynchus anatinus
100223892 Taeniopygia guttata
100354524 Oryctolagus cuniculus
100397041 Callithrix jacchus
100607262 Nomascus leucogenys
26047 Homo sapiens
66797 Mus musculus
500105 Rattus norvegicus
Selected quality suppliers for anti-CNTNAP2 (CNTNAP2) Antibodies
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