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Coordinator of PRMT5, Differentiation Stimulator Proteins (COPRS)

Histone-binding protein required for histone H4 methyltransferase activity of PRMT5. Additionally we are shipping Coordinator of PRMT5, Differentiation Stimulator Kits (5) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
COPRS 55352 Q9NQ92
COPRS 66423 Q9CQ13
COPRS 506999 A5PJD3
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Showing 3 out of 3 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
Yeast Cow His tag   1 mg Log in to see 56 to 66 Days
$2,440.17
Details

COPRS Proteins by Origin and Source

Origin Expressed in Conjugate
Human

Mouse (Murine)

Cow (Bovine)

More Proteins for Coordinator of PRMT5, Differentiation Stimulator (COPRS) Interaction Partners

Mouse (Murine) Coordinator of PRMT5, Differentiation Stimulator (COPRS) interaction partners

  1. Data extend the role of COPR5 from an adaptor protein required for nuclear functions of PRMT5 (show PRMT5 Proteins) to an essential coordinator of myogenic differentiation.

Coordinator of PRMT5, Differentiation Stimulator (COPRS) Protein Profile

Protein Summary

Histone-binding protein required for histone H4 methyltransferase activity of PRMT5. Specifically required for histone H4 'Arg-3' methylation mediated by PRMT5, but not histone H3 'Arg-8' methylation, suggesting that it modulates the substrate specificity of PRMT5. Specifically interacts with the N-terminus of histone H4 but not with histone H3, suggesting that it acts by promoting the association between histone H4 and PRMT5. Involved in CCNE1 promoter repression (By similarity).

Gene names and symbols associated with COPRS

  • chromosome 19 open reading frame, human C17orf79 (COPRS)
  • coordinator of PRMT5, differentiation stimulator (COPRS)
  • coordinator of PRMT5, differentiation stimulator (Coprs)
  • 1700029I03Rik protein
  • 2410022L05Rik protein
  • AA409325 protein
  • AI256813 protein
  • C17orf79 protein
  • C19H17orf79 protein
  • C85432 protein
  • Copr5 protein
  • HSA272196 protein
  • TTP1 protein

Protein level used designations for COPRS

cooperator of PRMT5 , coordinator of PRMT5 and differentiation stimulator

GENE ID SPECIES
506999 Bos taurus
55352 Homo sapiens
66423 Mus musculus
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