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anti-Copper Metabolism (Murr1) Domain Containing 1 (COMMD1) Antibodies

COMMD1 is a regulator of copper homeostasis, sodium uptake, and NF-kappa-B (see MIM 164011) signaling (de Bie et al., 2005 [PubMed 16267171]).[supplied by OMIM, Sep 2009].. Additionally we are shipping COMMD1 Kits (21) and COMMD1 Proteins (11) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
COMMD1 17846 Q8K4M5
COMMD1 150684 Q8N668
COMMD1 289831  
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Top anti-COMMD1 Antibodies at antibodies-online.com

Showing 10 out of 65 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated WB WB Suggested Anti-COMMD1 AntibodyTitration: 1.0 µg/mL  Positive Control: Fetal Heart 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Mouse Un-conjugated IP, ELISA, WB COMMD1 monoclonal antibody (M01), clone 2A12 Western Blot analysis of COMMD1 expression in HeLa . Detection limit for recombinant GST tagged COMMD1 is approximately 0.03ng/ml as a capture antibody. 100 μg Log in to see 9 Days
$430.00
Details
Human Mouse Un-conjugated FACS, IF, IHC (p), WB 100 μL Log in to see 8 to 10 Days
$493.17
Details
Human Mouse Un-conjugated FACS, IHC (p), WB 100 μL Log in to see 8 to 10 Days
$493.17
Details
Human Mouse Un-conjugated ELISA, WB COMMD1 polyclonal antibody (A01), Lot # 060802QCS1 Western Blot analysis of COMMD1 expression in HepG2 . COMMD1 polyclonal antibody (A01), Lot # 060802QCS1. Western Blot analysis of COMMD1 expression in NIH/3T3. 50 μL Log in to see 9 Days
$298.57
Details
Human Mouse Un-conjugated WB COMMD1 monoclonal antibody (M01), clone 2A12 Western Blot analysis of COMMD1 expression in HeLa. Detection limit for recombinant GST tagged COMMD1 is approximately 0.03 ng/mL as a capture antibody. 0.1 mg Log in to see 8 to 11 Days
$450.00
Details
Human Rabbit Un-conjugated EIA, IHC (fro), WB   0.2 mL Log in to see 6 to 8 Days
$533.50
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details
Human Mouse Un-conjugated FACS   100 μL Log in to see 8 to 10 Days
$493.17
Details
Human Mouse Un-conjugated WB Western Blot analysis of COMMD1 expression in transfected 293T cell line by COMMD1 MaxPab polyclonal antibody.Lane 1: COMMD1 transfected lysate(20.9 KDa).Lane 2: Non-transfected lysate. COMMD1 MaxPab polyclonal antibody. Western Blot analysis of COMMD1 expression in human placenta. 50 μL Log in to see 9 Days
$430.00
Details

COMMD1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-COMMD1 Antibodies

  1. Human Monoclonal COMMD1 Primary Antibody for IP, ELISA - ABIN566862 : Maine, Mao, Komarck, Burstein: COMMD1 promotes the ubiquitination of NF-kappaB subunits through a cullin-containing ubiquitin ligase. in The EMBO journal 2007 (PubMed)
    Show all 9 references for ABIN566862

  2. Human Polyclonal COMMD1 Primary Antibody for EIA, IHC (fro) - ABIN1106769 : Donadio, Alfaidy, De Keukeleire, Micoud, Feige, Challis, Benharouga: Expression and localization of cellular prion and COMMD1 proteins in human placenta throughout pregnancy. in Placenta 2007 (PubMed)

  3. Human Polyclonal COMMD1 Primary Antibody for ELISA, WB - ABIN566860 : Gkiafi, Panayotou: Comparative proteomic analysis implicates COMMD proteins as Epstein-Barr virus targets in the BL41 Burkitt's lymphoma cell line. in Journal of proteome research 2011 (PubMed)

More Antibodies against COMMD1 Interaction Partners

Mouse (Murine) Copper Metabolism (Murr1) Domain Containing 1 (COMMD1) interaction partners

  1. Liver specific Commd1 knockout results in elevated plasma LDL cholesterol.

  2. Alteration of COMMD1 concentration influences copper and zinc homeostasis as well as ProSAP/Shank (show SHANK2 Antibodies) protein levels.

  3. Copper metabolism domain-containing 1 represses genes that promote inflammation and protects mice from colitis and colitis-associated cancer.

  4. results provide the first genetic evidence for COMMD1 to play an essential role in hepatic copper homeostasis and present a valuable mouse model for further understanding of the molecular mechanisms underlying hepatic copper homeostasis

  5. Clusterin (show CLU Antibodies) and COMMD1 independently regulate degradation of the mammalian copper ATPases ATP7A (show ATP7A Antibodies) and ATP7B (show ATP7B Antibodies).

  6. COMMD1 as a novel protein regulating SOD1 activation and associate COMMD1 function with the production of free radicals.

  7. COMMD1 is required to shuttle the liver copper transporter (Atp7b (show ATP7B Antibodies)) when the intracellular copper level falls below the threshold.

  8. RNA polymerase II phosphorylated at serine 2 of the carboxyl-terminal domain repeats, a marker of transcription elongation, is enriched on the paternal allele than on the maternal allele in the Commd1 promoter

  9. Inhibition of histone deacetylases alters allelic chromatin conformation at the imprinted U2af1-rs1 locus in mouse embryonic stem cells

  10. A novel transcript (U2mu) in mouse is transcribed from the portions of two independent genes, U2af1-rs1 and Murr1.

Human Copper Metabolism (Murr1) Domain Containing 1 (COMMD1) interaction partners

  1. COMMD1 expression is associated with poor prognosis in diffuse large B-cell lymphoma

  2. COMMD1 is identified as a novel regulator of misfolded protein aggregation.

  3. COMMD1 is directly linked to early endosomes through its interaction with a protein complex containing CCDC22, CCDC93, and C16orf62.

  4. COMMD1 is acetylated by p300 (show EP300 Antibodies) and that acetylation protects COMMD1 from XIAP (show XIAP Antibodies)-mediated proteosomal degradation

  5. IkappaB-alpha (show NFKBIA Antibodies) protein was stabilized by COMMD1, which attenuated NF-kappaB (show NFKB1 Antibodies) signaling during Toll (show TLR4 Antibodies)-like receptor ligand and tumor necrosis factor alpha (show TNF Antibodies) treatment and enhanced HIV-1 latency in latently HIV-1-infected cells.

  6. These data demonstrate the anti-inflammatory properties of COMMD1 in bronchial epithelial cells and open new therapeutic avenues in cystic fibrosis (show S100A8 Antibodies).

  7. Placental COMMD1 expression is increased in women with severe preeclampsia compared to that found in women with normal pregnancies.

  8. The role of COMMD1 in copper metabolism and it structure and function are discussed.

  9. The results indicate a role for COMMD1 in the regulation of NKCC1 (show SLC12A2 Antibodies) membrane expression and ubiquitination.

  10. No major role can be attributed to Atox1 (show ATOX1 Antibodies) and COMMD in the pathophysiology or clinical variation of Wilson disease.

COMMD1 Antigen Profile

Protein Summary

COMMD1 is a regulator of copper homeostasis, sodium uptake, and NF-kappa-B (see MIM 164011) signaling (de Bie et al., 2005

Gene names and symbols associated with COMMD1

  • copper metabolism (Murr1) domain containing 1 (COMMD1) antibody
  • copper metabolism (Murr1) domain containing 1 (commd1) antibody
  • COMM domain containing 1 (Commd1) antibody
  • copper metabolism (Murr1) domain containing 1 (Commd1) antibody
  • AI256843 antibody
  • C2orf5 antibody
  • COMMD1 antibody
  • MGC114682 antibody
  • MURR1 antibody
  • U2/Mu antibody

Protein level used designations for COMMD1

copper metabolism (Murr1) domain containing 1 , MURR1 , COMM domain-containing protein 1 , U2af1-rs1 region 1 , copper metabolism domain containing 1 , protein Murr1 , copper metabolism gene MURR1

GENE ID SPECIES
459266 Pan troglodytes
734503 Xenopus laevis
748450 Pan troglodytes
769006 Gallus gallus
779529 Xenopus (Silurana) tropicalis
17846 Mus musculus
150684 Homo sapiens
534683 Bos taurus
403590 Canis lupus familiaris
289831 Rattus norvegicus
100731728 Cavia porcellus
101117656 Ovis aries
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