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Coproporphyrinogen Oxidase Proteins (CPOX)

The protein encoded by CPOX is the sixth enzyme of the heme biosynthetic pathway. Additionally we are shipping Coproporphyrinogen Oxidase Antibodies (17) and Coproporphyrinogen Oxidase Kits (12) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
CPOX 1371 P36551
CPOX 12892 P36552
CPOX 304024 Q3B7D0
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Top Coproporphyrinogen Oxidase Proteins at antibodies-online.com

Showing 5 out of 7 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
$2,937.00
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   100 μg Log in to see 3 to 4 Days
$382.86
Details

CPOX Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,
,
Mouse (Murine)

Rat (Rattus)

More Proteins for Coproporphyrinogen Oxidase (CPOX) Interaction Partners

Human Coproporphyrinogen Oxidase (CPOX) interaction partners

  1. The monomer form of mutated CPOX did not show any activity and homodimeric enzymes derived from Hereditary coproporphyria (HCP (show AMBP Proteins)) mutant showed low activity (<20% of the control).

  2. Polymorphism of coproporphyrinogen oxidase is associated with genetic susceptibility to the adverse neurobehavioral effects of Hg exposure in children.

  3. Deletion of the fifth exon in the CPOX gene is associated with hereditary coproporphyria.

  4. CPOX polymorphisms are associated with biological media contamination and apoptosis disorders.

  5. competitive action of both uroporphyrinogen decarboxylase (show UROD Proteins) and CPO on the same diacetate porphyrinogen substrate provides additional perspectives on the potential existence of abnormal pathways for heme biosynthesis

  6. disease-producing mutations in the CPO gene in nine Swedish families with hereditary coproporphyria

  7. coproporphyrinogen III oxidase sequence matches many structural features from urate oxidase (show UOX Proteins)

  8. Modulation of penetrance by the wild-type allele in dominantly inherited erythrohepatic and acute hepatic porphyrias was studied using CPO.

  9. All other type of mutations or missense mutations mapped elsewhere throughout the CPO gene, lead to coproporphyrin accumulation and subsequently typical HCP (show AMBP Proteins).

  10. CPO mutations form the structural basis of hereditary coproporphyria.

Mouse (Murine) Coproporphyrinogen Oxidase (CPOX) interaction partners

  1. The mechanisms by which impairment of CPOX leads to lens opacity in the NCT (show NCSTN Proteins) are elusive. However, our data illuminate a hitherto unanticipated involvement of the heme biosynthesis pathway in lens physiology.

Coproporphyrinogen Oxidase (CPOX) Protein Profile

Protein Summary

The protein encoded by this gene is the sixth enzyme of the heme biosynthetic pathway. The encoded enzyme is soluble and found in the intermembrane space of mitochondria. This enzyme catalyzes the stepwise oxidative decarboxylation of coproporphyrinogen III to protoporphyrinogen IX, a precursor of heme. Defects in this gene are a cause of hereditary coproporphyria (HCP).

Gene names and symbols associated with CPOX

  • coproporphyrinogen oxidase (cpox)
  • coproporphyrinogen oxidase (CPOX)
  • Coproporphyrinogen oxidase (Coprox)
  • coproporphyrinogen oxidase (CNE00980)
  • coproporphyrinogen oxidase (Shewana3_4102)
  • coproporphyrinogen oxidase (HemF_3)
  • coproporphyrinogen oxidase (Vapar_2685)
  • coproporphyrinogen III oxidase (hemF)
  • Coproporphyrinogen oxidase (Dd586_0781)
  • Coproporphyrinogen oxidase (BC1002_0909)
  • Coproporphyrinogen oxidase (Trad_0221)
  • coproporphyrinogen oxidase (Bresu_2732)
  • Coproporphyrinogen oxidase (Galf_2657)
  • Coproporphyrinogen oxidase (BC1003_2365)
  • coproporphyrinogen oxidase (Lbys_0733)
  • coproporphyrinogen oxidase (Ftrac_1490)
  • coproporphyrinogen oxidase (Astex_1139)
  • Coproporphyrinogen oxidase (BC1001_1038)
  • Coproporphyrinogen oxidase (Pedsa_0199)
  • Coproporphyrinogen oxidase (Fluta_2926)
  • Coproporphyrinogen oxidase (bgla_1g29750)
  • Coproporphyrinogen oxidase (Halhy_0288)
  • Coproporphyrinogen oxidase (Sphch_2673)
  • Coproporphyrinogen oxidase (Mesop_2259)
  • coproporphyrinogen oxidase (Cpox)
  • BcDNA:GM14838 protein
  • cb535 protein
  • CG3433 protein
  • Cpo protein
  • CPX protein
  • DDBDRAFT_0188158 protein
  • DDBDRAFT_0231414 protein
  • DDB_0188158 protein
  • DDB_0231414 protein
  • Dmel\\CG3433 protein
  • HCP protein
  • l(2)k10617 protein
  • l(2)k11018 protein
  • sb:cb535 protein
  • wu:fc43a01 protein

Protein level used designations for CPOX

coproporphyrinogen-III oxidase, mitochondrial , coproporphyrinogen oxidase , coproporphyrinogen-III oxidase, mitochondrial-like , CG3433-PA , Coprox-PA , Coproporphyrinogen oxidase , COX , coprogen oxidase , coproporphyrinogenase , Coproporphyrinogen III oxidase, mitochondrial precursor (Coproporphyrinogenase) (Coprogen oxidase) (COX) , clone 560

GENE ID SPECIES
321294 Danio rerio
418377 Gallus gallus
460544 Pan troglodytes
540283 Bos taurus
698849 Macaca mulatta
100145617 Xenopus (Silurana) tropicalis
100339410 Oryctolagus cuniculus
100389961 Callithrix jacchus
100442862 Pongo abelii
44701 Drosophila melanogaster
3257566 Cryptococcus neoformans var. neoformans JEC21
4480316 Shewanella sp. ANA-3
7200691 Phaeodactylum tricornutum CCAP 1055/1
7972284 Variovorax paradoxus S110
8626855 Dictyostelium discoideum AX4
8659700 Dickeya dadantii Ech586
9088579 Burkholderia sp. CCGE1002
9279191 Truepera radiovictrix DSM 17093
9504615 Brevundimonas subvibrioides ATCC 15264
9614026 Gallionella capsiferriformans ES-2
9767258 Burkholderia sp. CCGE1003
9954576 Leadbetterella byssophila DSM 17132
10011626 Marivirga tractuosa DSM 4126
10052703 Asticcacaulis excentricus CB 48
10222569 Burkholderia sp. CCGE1001
10229731 Pedobacter saltans DSM 12145
10398294 Fluviicola taffensis DSM 16823
10479504 Burkholderia gladioli BSR3
10584444 Haliscomenobacter hydrossis DSM 1100
10742945 Sphingobium chlorophenolicum L-1
10826092 Mesorhizobium opportunistum WSM2075
1371 Homo sapiens
12892 Mus musculus
304024 Rattus norvegicus
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