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CORIN encodes a member of the type II transmembrane serine protease class of the trypsin superfamily. Additionally we are shipping Corin Kits (34) and Corin Proteins (26) and many more products for this protein.
Showing 10 out of 65 products:
Human Monoclonal Corin Primary Antibody for ELISA, WB - ABIN393353
Bailey, Xie, Do, Montpetit, Diaz, Mohan, Keavney, Yusuf, Gerstein, Engert, Anand: Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study. in Diabetes Care 2010
Show all 5 references for ABIN393353
Human Polyclonal Corin Primary Antibody for EIA, WB - ABIN452862
Fox, Collard, Shernan, Seidman, Seidman, Liu, Muehlschlegel, Perry, Aranki, Lange, Herman, Meitinger, Lichtner, Body: Natriuretic peptide system gene variants are associated with ventricular dysfunction after coronary artery bypass grafting. in Anesthesiology 2009
Residues Lys (show LYZ Antibodies)-71, Phe-72 and Gln-73 serve as a novel retention motif in the intracellular pathway to regulate corin cell surface expression and activation.
N-glycans at different sites may play distinct roles in regulating the cell membrane targeting, zymogen activation, and ectodomain shedding of corin
These results provide the first experimental evidence that corin expression plays a role in cardiomyopathy by modulating myocardial fibrosis, cardiac function, heart failure, and survival.
Data show that KO/TgV mice had significantly higher levels of proatrial natriuretic peptide in the heart compared with that in control KO/TgWT mice, indicating that the corin variant was defective in processing natriuretic peptides in vivo.
Lack of corin in mice impairs their adaptive renal response to high dietary salt, suggesting that corin deficiency may represent an important mechanism underlying salt-sensitive hypertension.
results indicate that corin and ANP (show NPPA Antibodies) are essential for physiological changes at the maternal-fetal interface, suggesting that defects in corin and ANP (show NPPA Antibodies) function may contribute to pre-eclampsia
Data indicate that Corin's involvement in ANP (show NPPA Antibodies) processing is a key element in the heart's response to increased hemodynamic load
Ectodomain shedding and autocleavage of the cardiac membrane protease corin.
corin might be involved in the salt retention seen in glomerular diseases.
Insufficient corin activation is expected to prevent natriuretic peptide processing and may contribute to body fluid retention and impaired cardiac function in patients with heart failure.
Data show that both furin (show FURIN Antibodies) and brain type natriuretic peptide (BNP) were more sensitive than corin in predicting cardiovascular complications in type 2 diabetes mellitus (T2DM) patients.
Circulating corin concentrations are related to infarct size in patients after ST-segment elevation myocardial infarction
Hypertensive participants had an increased serum corin level compared to those without hypertension, suggesting that corin may play a role in the pathology of hypertension.
Serum soluble corin was significantly and positively associated with dyslipidemia
Plasma corin levels decreased significantly from preoperative concentrations after coronary artery bypass graft surgery.
corin may play an important role in the pathology of atrial fibrillation
Increased serum soluble corin in mid pregnancy was associated with an increased risk for HDP(hypertensive disorders of pregnancy) .--increased serum soluble corin in mid pregnancy could be an indicator for HDP
identified a PCSK6 (show PCSK6 Antibodies) mutation that impaired corin activation activity in a hypertensive patient
the variant altered corin structure and impaired the natriuretic peptide processing activity in vivo. The results highlight corin defects as an important underlying mechanism in hypertension.
IRE1 (show ERN1 Antibodies)-dependent corin mRNA decay is a mechanism leading to corin protein deficiency may contribute to the pathophysiology of impaired natriuretic peptide pro-hormone processing in humans processing in humans with advanced systolic heart failure.
This gene encodes a member of the type II transmembrane serine protease class of the trypsin superfamily. Members of this family are composed of multiple structurally distinct domains. The encoded protein converts pro-atrial natriuretic peptide to biologically active atrial natriuretic peptide, a cardiac hormone that regulates blood volume and pressure. This protein may also function as a pro-brain-type natriuretic peptide convertase.
corin, serine peptidase
, novel protein similar to H.sapiens CORIN, corin, serine peptidase (CORIN)
, atrial natriuretic peptide-converting enzyme-like
, atrial natriuretic peptide-converting enzyme
, low density lipoprotein receptor-related protein 4
, low density lipoprotein-related protein 4
, pro-ANP-converting enzyme
, heart-specific serine proteinase ATC2
, transmembrane protease serine 10