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Corin, Serine Peptidase Proteins (CORIN)

CORIN encodes a member of the type II transmembrane serine protease class of the trypsin superfamily. Additionally we are shipping Corin Antibodies (67) and Corin Kits (34) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
CORIN 53419 Q9Z319
CORIN 10699 Q9Y5Q5
CORIN 289596 Q80YN4
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Top Corin Proteins at antibodies-online.com

Showing 10 out of 26 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 49 to 54 Days
$4,244.78
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 49 to 54 Days
$6,041.49
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 39 to 44 Days
$9,248.02
Details
HOST_Escherichia coli (E. coli) Human His tag,GST tag 100 μg Log in to see 11 to 13 Days
$668.80
Details
HOST_Escherichia coli (E. coli) Mouse His tag,T7 tag 100 μg Log in to see 11 to 13 Days
$721.60
Details
HOST_Escherichia coli (E. coli) Rat His tag 100 μg Log in to see 11 to 13 Days
$844.80
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   100 μg Log in to see 9 to 19 Days
$841.86
Details
HOST_Escherichia coli (E. coli) Mouse Un-conjugated   100 μg Log in to see 9 to 19 Days
$904.80
Details

CORIN Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine) ,
, ,
Human , , ,
, , , ,
Rat (Rattus)

More Proteins for Corin, Serine Peptidase (CORIN) Interaction Partners

Mouse (Murine) Corin, Serine Peptidase (CORIN) interaction partners

  1. Residues Lys (show LYZ Proteins)-71, Phe-72 and Gln-73 serve as a novel retention motif in the intracellular pathway to regulate corin cell surface expression and activation.

  2. N-glycans at different sites may play distinct roles in regulating the cell membrane targeting, zymogen activation, and ectodomain shedding of corin

  3. These results provide the first experimental evidence that corin expression plays a role in cardiomyopathy by modulating myocardial fibrosis, cardiac function, heart failure, and survival.

  4. Data show that KO/TgV mice had significantly higher levels of proatrial natriuretic peptide in the heart compared with that in control KO/TgWT mice, indicating that the corin variant was defective in processing natriuretic peptides in vivo.

  5. Lack of corin in mice impairs their adaptive renal response to high dietary salt, suggesting that corin deficiency may represent an important mechanism underlying salt-sensitive hypertension.

  6. results indicate that corin and ANP (show NPPA Proteins) are essential for physiological changes at the maternal-fetal interface, suggesting that defects in corin and ANP (show NPPA Proteins) function may contribute to pre-eclampsia

  7. Data indicate that Corin's involvement in ANP (show NPPA Proteins) processing is a key element in the heart's response to increased hemodynamic load

  8. Ectodomain shedding and autocleavage of the cardiac membrane protease corin.

  9. corin might be involved in the salt retention seen in glomerular diseases.

  10. Insufficient corin activation is expected to prevent natriuretic peptide processing and may contribute to body fluid retention and impaired cardiac function in patients with heart failure.

Human Corin, Serine Peptidase (CORIN) interaction partners

  1. serum levels of corin are significantly decreased in acute myocardial infarction patients

  2. Data show that both furin (show FURIN Proteins) and brain type natriuretic peptide (BNP) were more sensitive than corin in predicting cardiovascular complications in type 2 diabetes mellitus (T2DM) patients.

  3. Circulating corin concentrations are related to infarct size in patients after ST-segment elevation myocardial infarction

  4. Hypertensive participants had an increased serum corin level compared to those without hypertension, suggesting that corin may play a role in the pathology of hypertension.

  5. Serum soluble corin was significantly and positively associated with dyslipidemia

  6. Plasma corin levels decreased significantly from preoperative concentrations after coronary artery bypass graft surgery.

  7. corin may play an important role in the pathology of atrial fibrillation

  8. Increased serum soluble corin in mid pregnancy was associated with an increased risk for HDP(hypertensive disorders of pregnancy) .--increased serum soluble corin in mid pregnancy could be an indicator for HDP

  9. identified a PCSK6 mutation that impaired corin activation activity in a hypertensive patient

  10. the variant altered corin structure and impaired the natriuretic peptide processing activity in vivo. The results highlight corin defects as an important underlying mechanism in hypertension.

Corin (CORIN) Protein Profile

Protein Summary

This gene encodes a member of the type II transmembrane serine protease class of the trypsin superfamily. Members of this family are composed of multiple structurally distinct domains. The encoded protein converts pro-atrial natriuretic peptide to biologically active atrial natriuretic peptide, a cardiac hormone that regulates blood volume and pressure. This protein may also function as a pro-brain-type natriuretic peptide convertase.

Gene names and symbols associated with CORIN

  • corin, serine peptidase (CORIN)
  • CG2105 gene product from transcript CG2105-RC (Corin)
  • novel protein similar to H.sapiens CORIN, corin, serine peptidase (CORIN) (CH1073-76A20.1)
  • corin (Corin)
  • corin (LOC100340894)
  • corin, serine peptidase (Corin)
  • ATC2 protein
  • AV273130 protein
  • CG2105 protein
  • CORIN protein
  • CRN protein
  • Dmel\\CG2105 protein
  • LOC559109 protein
  • Lrp4 protein
  • PEE5 protein
  • SP75 protein
  • TMPRSS10 protein

Protein level used designations for CORIN

corin, serine peptidase , CG2105-PB , CG2105-PC , Corin-PB , Corin-PC , DCorin , corin , novel protein similar to H.sapiens CORIN, corin, serine peptidase (CORIN) , atrial natriuretic peptide-converting enzyme-like , atrial natriuretic peptide-converting enzyme , low density lipoprotein receptor-related protein 4 , low density lipoprotein-related protein 4 , pro-ANP-converting enzyme , heart-specific serine proteinase ATC2 , pro-ANP-convertase , transmembrane protease serine 10

GENE ID SPECIES
100054484 Equus caballus
740125 Pan troglodytes
35691 Drosophila melanogaster
559109 Danio rerio
704666 Macaca mulatta
100397961 Callithrix jacchus
100467817 Ailuropoda melanoleuca
100595353 Nomascus leucogenys
53419 Mus musculus
100340894 Oryctolagus cuniculus
10699 Homo sapiens
289596 Rattus norvegicus
482135 Canis lupus familiaris
527107 Bos taurus
100857733 Gallus gallus
100720071 Cavia porcellus
Selected quality suppliers for Corin Proteins (CORIN)
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