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CORO1C encodes a member of the WD repeat protein family. Additionally we are shipping CORO1C Antibodies (69) and CORO1C Proteins (5) and many more products for this protein.
Coronin-1C Protein and Caveolin Protein Provide Constitutive and Inducible Mechanisms of Rac1 Protein
Coronin 1C displays highly co-operative binding to actin filaments. We highlight a novel mode of coronin regulation, which has implications for how coronins orchestrate cytoskeletal dynamics.
These results indicate that glucose recruits coronin 3 near the plasma membrane, and that it regulates the retrograde transport of the secretory membrane in pancreatic beta-cells.
Coronin 3 is abundantly expressed in the adult CNS. All murine brain areas express coronin 3 during embryogenesis and the first postnatal stages.
Results indicate that interaction of GDP-Rab27a (show RAB27A ELISA Kits) and coronin 3 is important in stimulus-endocytosis coupling, and that GTP (show AK3 ELISA Kits)- and GDP-Rab27a (show RAB27A ELISA Kits) regulates insulin (show INS ELISA Kits) membrane recycling at the distinct stages.
findings emphasize the power of genetic modifiers, PLS3 (show PLS3 ELISA Kits) and CORO1C, to unravel the cellular pathomechanisms underlying spinal muscular atrophy (SMA (show SMN1 ELISA Kits))--and the power of combinatorial therapy based on splice correction of SMN2 (show SMN1 ELISA Kits) and endocytosis improvement to efficiently treat SMA (show SMN1 ELISA Kits)
Data indicate that coronin 1C protein (CORO1C) was a direct target of the microRNA miR-1/133a cluster in EBC-1 CORO1C was a direct target of the miR-1/133a cluster in lung-squamous cell carcinoma cell line EBC-1.
Coro1C mediated Rac1 trafficking through actin-rich vesicles.
Coronin-1C overexpression is associated withand hepatocellular carcinoma growth through enhancement of tumor cell proliferation and migration, which are correlated with Rac-1 activation.
Coronin 3 promotes gastric cancer metastasis via the up-regulation of MMP-9 (show MMP9 ELISA Kits) and cathepsin K (show CTSK ELISA Kits).
Patients with higher coronin-1C expression had a more advanced stage of hepatocellular carcinoma.
There is a strong expression of both SELPLG and coronin-1C in the majority of primary effusion lymphomas, irrespective of their gene dosage. SELPLG is critical for cell migration and chemotaxis, while CORO1C regulates actin-dependent processes.
Coronin 1C negatively regulates epithelial cell migration via FAK (show PTK2 ELISA Kits)-mediated inhibition of cell-matrix adhesion.
oligomerization, F-actin interaction and membrane association are mediated by carboxyl terminus
We show that coronin 3 similar to other coronins interacts with the Arp2 (show ACTR2 ELISA Kits)/3-complex and cofilin (show CFL1 ELISA Kits) indicating that this family in general is involved in regulating Arp2 (show ACTR2 ELISA Kits)/3-mediated events.
This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. Three transcript variants encoding two different isoforms have been found for this gene.
coronin, actin binding protein, 1C
, coronin homolog
, coronin 1c
, coronin 3
, coronin 1C
, coronin, actin-binding protein, 1C