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anti-Corticotropin Releasing Hormone Receptor 1 (CRHR1) Antibodies

CRHR1 encodes a G-protein coupled receptor that binds neuropeptides of the corticotropin releasing hormone family that are major regulators of the hypothalamic-pituitary-adrenal pathway. Additionally we are shipping CRHR1 Kits (13) and CRHR1 Proteins (8) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
CRHR1 1394 P34998
CRHR1 12921 P35347
CRHR1 58959 P35353
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Top anti-CRHR1 Antibodies at antibodies-online.com

Showing 10 out of 154 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Goat Un-conjugated IHC, ELISA, WB ABIN238557 (0.1 µg/mL) staining of human colon lysate (35 µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. Confocal image (3 µm) of ABIN238557 (0.3 µg/mL) staining in green a dendrite of a neuronal cell in C57 mouse cortex. Counter-stained with DAPI (in blue). Data kindly provided by Dr Y. Chen, TZ Baram lab, UC Irvine, CA. 100 μg Log in to see 4 to 5 Days
$318.20
Details
Human Goat Un-conjugated IHC (fro), IF, WB 0.1 mg Log in to see 6 to 8 Days
$379.50
Details
Human Rabbit Un-conjugated EIA, FACS, WB CRFR1 Antibody (Q103) flow cytometric analysis of K562 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. CRFR1 Antibody western blot analysis in K562 cell line lysates (35µg/lane).This demonstrates the CRFR1 antibody detected the CRFR1 protein (arrow). 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated IF, ELISA, WB Western blot analysis of extracts from HT-29/LOVO cells, using CRHR1 Antibody. The lane on the right is treated with the synthesized peptide. Immunofluorescence analysis of MCF7 cells, using CRHR1 Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Cow Goat Un-conjugated EIA, IF, IHC (p)   0.1 mg Log in to see 6 to 8 Days
$379.50
Details
Mouse Goat Un-conjugated IHC, ELISA, WB   100 μg Log in to see 4 to 5 Days
$318.20
Details
Human Rabbit Un-conjugated FACS, WB CRFR1 Antibody (Q103)  western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the CRFR1 antibody detected the CRFR1 protein (arrow). CRFR1 Antibody (Q103)  flow cytometric analysis of K562 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated IHC (p), WB WB Image Sample (50 ug of whole cell lysate) A: Mouse brain 10% SDS PAGE antibody diluted at 1:500 IHC-P Image Immunohistochemical analysis of paraffin-embedded HeLa xenograft, using CRFR1, antibody at 1:500 dilution. 100 μL Log in to see 2 to 3 Days
$358.60
Details
Human Rabbit Un-conjugated IHC (p) Anti-CRF1 antibody  ABIN1048461 IHC staining of rat hypothlalmus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Anti-CRF1 antibody  ABIN1048461 IHC staining of human human brain, neurons and glia. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. 50 μg Log in to see 8 to 10 Days
$451.00
Details
Human Rabbit Un-conjugated IHC (p) Anti-CRF1 antibody  ABIN1048462 IHC staining of human pituitary. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. 50 μg Log in to see 8 to 10 Days
$451.00
Details

CRHR1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-CRHR1 Antibodies

  1. Human Polyclonal CRHR1 Primary Antibody for IHC, ELISA - ABIN238557 : Rissman, Lee, Vale, Sawchenko: Corticotropin-releasing factor receptors differentially regulate stress-induced tau phosphorylation. in The Journal of neuroscience : the official journal of the Society for Neuroscience 2007 (PubMed)
    Show all 3 references for ABIN238557

  2. Human Polyclonal CRHR1 Primary Antibody for EIA, FACS - ABIN951703 : Karteris, Markovic, Chen, Hillhouse, Grammatopoulos: Identification of a novel corticotropin-releasing hormone type 1beta-like receptor variant lacking Exon 13 in human pregnant myometrium regulated by estradiol-17beta and progesterone. in Endocrinology 2010 (PubMed)
    Show all 3 references for ABIN951703

  3. Human Polyclonal CRHR1 Primary Antibody for IHC (fro), IF - ABIN374874 : Jüngling, Liu, Lesting, Coulon, Sosulina, Reinscheid, Pape: Activation of neuropeptide S-expressing neurons in the locus coeruleus by corticotropin-releasing factor. in The Journal of physiology 2012 (PubMed)
    Show all 2 references for ABIN374874

  4. Human Polyclonal CRHR1 Primary Antibody for IF, ELISA - ABIN1535580 : Kageyama, Hasegawa, Akimoto, Yamagata, Tamasawa, Suda: Differential regulation of gonadotropin-releasing hormone by corticotropin-releasing factor family peptides in hypothalamic N39 cells. in Peptides 2011 (PubMed)
    Show all 2 references for ABIN1535580

  5. Mouse (Murine) Polyclonal CRHR1 Primary Antibody for IHC, ELISA - ABIN190893 : Ungless, Singh, Crowder, Yaka, Ron, Bonci: Corticotropin-releasing factor requires CRF binding protein to potentiate NMDA receptors via CRF receptor 2 in dopamine neurons. in Neuron 2003 (PubMed)

More Antibodies against CRHR1 Interaction Partners

Pig (Porcine) Corticotropin Releasing Hormone Receptor 1 (CRHR1) interaction partners

  1. CRFr1 activation mediates intestinal mucosa barrier dysfunction and hypersecretion in early-weaned piglets, whereas CRFr2 (show CRHR2 Antibodies) activation may be responsible for novel protective properties in the porcine intestine in response to early life stress.

Horse (Equine) Corticotropin Releasing Hormone Receptor 1 (CRHR1) interaction partners

  1. The expression of UCN, CRHR1, CRHR2 and CRHBP by immunohistochemistry, Western blot and reverse transcription with the polymerase chain reaction (RT-PCR) in the horse thyroid gland, was investigated

Human Corticotropin Releasing Hormone Receptor 1 (CRHR1) interaction partners

  1. results found that among children with no copies of the protective CRHR1 TAT (show TAT Antibodies) haplotype, children of mothers with a history of Manic Depressive Disorder had significantly higher levels of brooding than children of mothers with no history of depression.

  2. The CRHR1 gene reduces the risk for depressive symptoms among youths living in families undergoing high levels of economic hardship.

  3. CAL (show FBLIM1 Antibodies) can regulate the anterograde trafficking, the internalization as well as the signaling of CRFR1 via modulating the post-translational modifications that the receptor undergoes at the Golgi apparatus.

  4. CRF-R1 activation by CRF (show CRH Antibodies) and UCN (show UCN Antibodies) inhibits the proliferation of SK-N-SH (N) cells and promotes neuronal-like differentiation.

  5. The results revealed that changes in depressive symptoms over time depended on both intervention group and genotypes (5-HTTLPR (show SLC6A4 Antibodies) and CRHR1).

  6. CRHR1 gene SNP rs242941 polymorphism is associated with better response to systemic corticosteroid during acute exacerbation of asthma.

  7. Study provides data pointing out the critical role of corticotropin-releasing factor (show CRH Antibodies), through CRF1R, in the positive reinforcing effects of morphine and in morphine-conducted behaviours

  8. The results suggested no association between the CRHR1 gene single nucleotide polymorphisms and infantile spasms in a Chinese population.

  9. the present study demonstrates that the expression of CRH/CRH (show CRH Antibodies)-R1 in lesions of chronic plaque psoriasis is lower than that in psoriatic perilesional skin and normal control skin.

  10. The involvement of CRHR1 in ND.

Mouse (Murine) Corticotropin Releasing Hormone Receptor 1 (CRHR1) interaction partners

  1. Data suggest a physiologically relevant role for local corticotropin-releasing hormone (show CRH Antibodies) signaling towards shaping the neuronal circuitry within the mouse olfactory bulb.

  2. A role was found for extra-hypothalamic CRF-R1 in stress-escalated alcohol drinking.

  3. This study demonstrated that an anatomical mechanism for sex-differences in the convergent modulation of ventrolateral medulla catecholaminergic neurons by CRF (show CRH Antibodies) and glutamate (show GRIN1 Antibodies).

  4. these results indicate that NPS-NPSR system may regulate locomotion together with the CRF1 system in SN.

  5. bladder smooth muscle contractility is unchanged by CsA (show HSPA9 Antibodies); however, there are changes in the levels of the downstream transcription factors MEF-2 (show MYEF2 Antibodies) and NFAT (show NFATC1 Antibodies).

  6. The genetic disruption of the CRF1R pathway decreased the period of extinction in males and females suggesting that CRF (show CRH Antibodies)/CRF1R is implicated in the duration of aversive memory.

  7. Anatomical and biochemical findings demonstrate that accumulation of Abeta (show APP Antibodies) is significantly reduced in the brain of Alzheimer's disease model mice lacking CRFR1 providing support for a direct relationship between CRFR1 and Abeta (show APP Antibodies) production pathways

  8. Results reveal the influences of early postnatal stress on the development of medial prefrontal cortex (mPFC) pyramidal neurons, and highlights CRF1 as a key molecule in modulating the detrimental stress effects on the structural organizations of mPFC

  9. it is shown that CRH (show CRH Antibodies) and UCN (show UCN Antibodies) upregulate galectin-1 (show LGALS1 Antibodies) expression in Ishikawa cell line and macrophages and this effect is mediated through CRHR1.

  10. This study aims to investigate the cellular localization of CRF (show CRH Antibodies) and UCNs in the ileum and to explore whether and how this cellular expression is altered in conditions of intestinal Schistosoma mansoni-induced inflammation.

Cow (Bovine) Corticotropin Releasing Hormone Receptor 1 (CRHR1) interaction partners

  1. These results suggest that a regulatory system exists in the bovine thyroid gland based on UCN (show UCN Antibodies), CRHR1 and CRHR2 (show CRHR2 Antibodies) and that UCN (show UCN Antibodies) plays a role in the regulation of thyroid physiological functions through an autocrine/paracrine mechanism.

  2. CRHR1 and CRHR2 (show CRHR2 Antibodies) are expressed in the bovine adrenal gland.

  3. results indicate that arginine vasopressin (show AVP Antibodies) receptor V3 and corticotropin-releasing factor receptor 1 mRNAs are coordinately downregulated in the anterior pituitary during systemic inflammatory stress in cattle[AVP receptor V3 (show AVPR1B Antibodies)]

Rhesus Monkey Corticotropin Releasing Hormone Receptor 1 (CRHR1) interaction partners

  1. The results of this study suggested that variation in CRHR1 may influence brain function before any childhood adversity and may be a diathesis for the interaction between CRHR1 genotypes and childhood trauma reported to affect human psychopathology

Xenopus laevis Corticotropin Releasing Hormone Receptor 1 (CRHR1) interaction partners

  1. CRF (show CRH Antibodies) is expressed in tadpole tail, is up-regulated by environmental stressors, and is cytoprotective

CRHR1 Antigen Profile

Protein Summary

This gene encodes a G-protein coupled receptor that binds neuropeptides of the corticotropin releasing hormone family that are major regulators of the hypothalamic-pituitary-adrenal pathway. The encoded protein is essential for the activation of signal transduction pathways that regulate diverse physiological processes including stress, reproduction, immune response and obesity. Alternative splicing results in multiple transcript variants, one of which represents a read-through transcript with the neighboring gene MGC57346.

Gene names and symbols associated with CRHR1

  • corticotropin releasing hormone receptor 1 (CRHR1) antibody
  • corticotropin releasing hormone receptor 1 (Crhr1) antibody
  • corticotropin releasing hormone receptor 1, gene 2 (crhr1.2) antibody
  • CRF-R antibody
  • CRF-R-1 antibody
  • CRF-R1 antibody
  • CRF1 antibody
  • CRFR-1 antibody
  • CRFR1 antibody
  • CRH-R-1 antibody
  • CRH-R1 antibody
  • CRH-R1h antibody
  • Crhr antibody
  • crhr1 antibody
  • crhr1-A antibody
  • CRHR1f antibody
  • CRHR1L antibody

Protein level used designations for CRHR1

corticotropin releasing hormone receptor type I , corticotropin-releasing factor receptor 1 , corticotropin releasing hormone receptor 1 , corticotropin releasing hormone receptor variant 1e , corticotropin releasing hormone receptor variant 1g , corticotropin-releasing factor type 1 receptor , corticotropin-releasing hormone receptor 1 , seven transmembrane helix receptor , CRF 1 receptor , CRF-R-1 , CRF-R1 , CRF-R1alpha , CRFR-1 , CRH-R-1 , CRH-R1 , CRF-R , CRF1 , CRH-R 1 , corticotrophin releasing hormone receptor 1 , corticotropin releasing hormone 1 , corticotropin releasing factor receptor type 1 , corticotrophin-releasing factor type 1 alpha receptor

GENE ID SPECIES
397426 Sus scrofa
468283 Pan troglodytes
723971 Felis catus
100065598 Equus caballus
1394 Homo sapiens
12921 Mus musculus
58959 Rattus norvegicus
610380 Canis lupus familiaris
281716 Bos taurus
443025 Ovis aries
100302436 Oryctolagus cuniculus
374218 Gallus gallus
574095 Macaca mulatta
373580 Xenopus laevis
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