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CRHR1 encodes a G-protein coupled receptor that binds neuropeptides of the corticotropin releasing hormone family that are major regulators of the hypothalamic-pituitary-adrenal pathway. Additionally we are shipping CRHR1 Kits (13) and CRHR1 Proteins (8) and many more products for this protein.
Showing 10 out of 162 products:
Human Polyclonal CRHR1 Primary Antibody for IHC, ELISA - ABIN238557
Rissman, Lee, Vale, Sawchenko: Corticotropin-releasing factor receptors differentially regulate stress-induced tau phosphorylation. in The Journal of neuroscience : the official journal of the Society for Neuroscience 2007
Show all 3 references for ABIN238557
Human Polyclonal CRHR1 Primary Antibody for EIA, FACS - ABIN951703
Karteris, Markovic, Chen, Hillhouse, Grammatopoulos: Identification of a novel corticotropin-releasing hormone type 1beta-like receptor variant lacking Exon 13 in human pregnant myometrium regulated by estradiol-17beta and progesterone. in Endocrinology 2010
Show all 3 references for ABIN951703
Human Polyclonal CRHR1 Primary Antibody for ICC, IF - ABIN314277
Xu, Rabadan-Diehl, Nikodemova, Wynn, Spiess, Aguilera: Inhibition of corticotropin releasing hormone type-1 receptor translation by an upstream AUG triplet in the 5' untranslated region. in Molecular pharmacology 2001
Show all 3 references for ABIN314277
Human Polyclonal CRHR1 Primary Antibody for IF, ELISA - ABIN1535580
Kageyama, Hasegawa, Akimoto, Yamagata, Tamasawa, Suda: Differential regulation of gonadotropin-releasing hormone by corticotropin-releasing factor family peptides in hypothalamic N39 cells. in Peptides 2011
Show all 2 references for ABIN1535580
Human Polyclonal CRHR1 Primary Antibody for IHC (fro), IF - ABIN374874
Jüngling, Liu, Lesting, Coulon, Sosulina, Reinscheid, Pape: Activation of neuropeptide S-expressing neurons in the locus coeruleus by corticotropin-releasing factor. in The Journal of physiology 2012
Show all 2 references for ABIN374874
Mouse (Murine) Polyclonal CRHR1 Primary Antibody for IHC, ELISA - ABIN190893
Ungless, Singh, Crowder, Yaka, Ron, Bonci: Corticotropin-releasing factor requires CRF binding protein to potentiate NMDA receptors via CRF receptor 2 in dopamine neurons. in Neuron 2003
Human Polyclonal CRHR1 Primary Antibody for IHC (p) - ABIN4300460
Lemos, Wanat, Smith, Reyes, Hollon, Van Bockstaele, Chavkin, Phillips: Severe stress switches CRF action in the nucleus accumbens from appetitive to aversive. in Nature 2012
Human Monoclonal CRHR1 Primary Antibody for FACS - ABIN4896738
Alysandratos, Asadi, Angelidou, Zhang, Sismanopoulos, Yang, Critchfield, Theoharides: Neurotensin and CRH interactions augment human mast cell activation. in PLoS ONE 2012
CRFr1 activation mediates intestinal mucosa barrier dysfunction and hypersecretion in early-weaned piglets, whereas CRFr2 (show CRHR2 Antibodies) activation may be responsible for novel protective properties in the porcine intestine in response to early life stress.
The expression of UCN, CRHR1, CRHR2 and CRHBP by immunohistochemistry, Western blot and reverse transcription with the polymerase chain reaction (RT-PCR) in the horse thyroid gland, was investigated
This study showed that associations between BPD (show MOD(MDG4) Antibodies) and haplotype combinations of the genes FKBP5 (show FKBP5 Antibodies) and CRHR1.
replicated the initially reported association of the CRHR1 rs878886 G-allele with cued fear acquisition deficits, albeit with a different pattern of results regarding the interaction with 5-HTT (show SLC6A4 Antibodies) variation
hsa (show CD24 Antibodies)-miR (show MLXIP Antibodies)-34a can regulate the CRH (show CRH Antibodies)/CRHR1/POMC (show POMC Antibodies) axis and may influence body mass index.
results found that among children with no copies of the protective CRHR1 TAT (show TAT Antibodies) haplotype, children of mothers with a history of Manic Depressive Disorder had significantly higher levels of brooding than children of mothers with no history of depression.
The CRHR1 gene reduces the risk for depressive symptoms among youths living in families undergoing high levels of economic hardship.
CAL (show FBLIM1 Antibodies) can regulate the anterograde trafficking, the internalization as well as the signaling of CRFR1 via modulating the post-translational modifications that the receptor undergoes at the Golgi apparatus.
CRF-R1 activation by CRF (show CRH Antibodies) and UCN (show UCN Antibodies) inhibits the proliferation of SK-N-SH (N) cells and promotes neuronal-like differentiation.
The results revealed that changes in depressive symptoms over time depended on both intervention group and genotypes (5-HTTLPR (show SLC6A4 Antibodies) and CRHR1).
CRHR1 gene SNP rs242941 polymorphism is associated with better response to systemic corticosteroid during acute exacerbation of asthma.
Study provides data pointing out the critical role of corticotropin-releasing factor (show CRH Antibodies), through CRF1R, in the positive reinforcing effects of morphine and in morphine-conducted behaviours
Data suggest a physiologically relevant role for local corticotropin-releasing hormone (show CRH Antibodies) signaling towards shaping the neuronal circuitry within the mouse olfactory bulb.
A role was found for extra-hypothalamic CRF-R1 in stress-escalated alcohol drinking.
This study demonstrated that an anatomical mechanism for sex-differences in the convergent modulation of ventrolateral medulla catecholaminergic neurons by CRF (show CRH Antibodies) and glutamate (show GRIN1 Antibodies).
these results indicate that NPS-NPSR system may regulate locomotion together with the CRF1 system in SN.
bladder smooth muscle contractility is unchanged by CsA (show HSPA9 Antibodies); however, there are changes in the levels of the downstream transcription factors MEF-2 (show MYEF2 Antibodies) and NFAT (show NFATC1 Antibodies).
The genetic disruption of the CRF1R pathway decreased the period of extinction in males and females suggesting that CRF (show CRH Antibodies)/CRF1R is implicated in the duration of aversive memory.
Anatomical and biochemical findings demonstrate that accumulation of Abeta (show APP Antibodies) is significantly reduced in the brain of Alzheimer's disease model mice lacking CRFR1 providing support for a direct relationship between CRFR1 and Abeta (show APP Antibodies) production pathways
Results reveal the influences of early postnatal stress on the development of medial prefrontal cortex (mPFC) pyramidal neurons, and highlights CRF1 as a key molecule in modulating the detrimental stress effects on the structural organizations of mPFC
it is shown that CRH (show CRH Antibodies) and UCN (show UCN Antibodies) upregulate galectin-1 (show LGALS1 Antibodies) expression in Ishikawa cell line and macrophages and this effect is mediated through CRHR1.
This study aims to investigate the cellular localization of CRF (show CRH Antibodies) and UCNs in the ileum and to explore whether and how this cellular expression is altered in conditions of intestinal Schistosoma mansoni-induced inflammation.
These results suggest that a regulatory system exists in the bovine thyroid gland based on UCN (show UCN Antibodies), CRHR1 and CRHR2 (show CRHR2 Antibodies) and that UCN (show UCN Antibodies) plays a role in the regulation of thyroid physiological functions through an autocrine/paracrine mechanism.
CRHR1 and CRHR2 (show CRHR2 Antibodies) are expressed in the bovine adrenal gland.
results indicate that arginine vasopressin (show AVP Antibodies) receptor V3 and corticotropin-releasing factor receptor 1 mRNAs are coordinately downregulated in the anterior pituitary during systemic inflammatory stress in cattle[AVP receptor V3 (show AVPR1B Antibodies)]
The results of this study suggested that variation in CRHR1 may influence brain function before any childhood adversity and may be a diathesis for the interaction between CRHR1 genotypes and childhood trauma reported to affect human psychopathology
CRF (show CRH Antibodies) is expressed in tadpole tail, is up-regulated by environmental stressors, and is cytoprotective
This gene encodes a G-protein coupled receptor that binds neuropeptides of the corticotropin releasing hormone family that are major regulators of the hypothalamic-pituitary-adrenal pathway. The encoded protein is essential for the activation of signal transduction pathways that regulate diverse physiological processes including stress, reproduction, immune response and obesity. Alternative splicing results in multiple transcript variants, one of which represents a read-through transcript with the neighboring gene MGC57346.
corticotropin releasing hormone receptor type I
, corticotropin-releasing factor receptor 1
, corticotropin releasing hormone receptor 1
, corticotropin releasing hormone receptor variant 1e
, corticotropin releasing hormone receptor variant 1g
, corticotropin-releasing factor type 1 receptor
, corticotropin-releasing hormone receptor 1
, seven transmembrane helix receptor
, CRF 1 receptor
, CRH-R 1
, corticotrophin releasing hormone receptor 1
, corticotropin releasing hormone 1
, corticotropin releasing factor receptor type 1
, corticotrophin-releasing factor type 1 alpha receptor