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Corticotropin Releasing Hormone Receptor 1 Proteins (CRHR1)

CRHR1 encodes a G-protein coupled receptor that binds neuropeptides of the corticotropin releasing hormone family that are major regulators of the hypothalamic-pituitary-adrenal pathway. Additionally we are shipping CRHR1 Antibodies (154) and CRHR1 Kits (13) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
CRHR1 1394 P34998
CRHR1 12921 P35347
Rat CRHR1 CRHR1 58959 P35353
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Top CRHR1 Proteins at antibodies-online.com

Showing 7 out of 8 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 49 to 54 Days
$4,244.78
Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 49 to 54 Days
$6,041.49
Details
Yeast Human His tag 50 μg Log in to see 31 to 36 Days
$341.00
Details
HOST_Escherichia coli (E. coli) Human GST tag 50 μg Log in to see 21 to 26 Days
$341.00
Details
HOST_Wheat germ Human Un-conjugated   10 μg Log in to see 9 Days
$641.43
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   50 μg Log in to see 16 to 21 Days
$314.29
Details

CRHR1 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , , ,
, ,
Mouse (Murine)

Top referenced CRHR1 Proteins

  1. Human CRHR1 Protein expressed in Wheat germ - ABIN1350338 : Xu, Xu, Hennebold, Molskness, Stouffer: Expression and role of the corticotropin-releasing hormone/urocortin-receptor-binding protein system in the primate corpus luteum during the menstrual cycle. in Endocrinology 2007 (PubMed)

More Proteins for Corticotropin Releasing Hormone Receptor 1 (CRHR1) Interaction Partners

Pig (Porcine) Corticotropin Releasing Hormone Receptor 1 (CRHR1) interaction partners

  1. CRFr1 activation mediates intestinal mucosa barrier dysfunction and hypersecretion in early-weaned piglets, whereas CRFr2 (show CRHR2 Proteins) activation may be responsible for novel protective properties in the porcine intestine in response to early life stress.

Horse (Equine) Corticotropin Releasing Hormone Receptor 1 (CRHR1) interaction partners

  1. The expression of UCN, CRHR1, CRHR2 and CRHBP by immunohistochemistry, Western blot and reverse transcription with the polymerase chain reaction (RT-PCR) in the horse thyroid gland, was investigated

Human Corticotropin Releasing Hormone Receptor 1 (CRHR1) interaction partners

  1. results found that among children with no copies of the protective CRHR1 TAT (show TAT Proteins) haplotype, children of mothers with a history of Manic Depressive Disorder had significantly higher levels of brooding than children of mothers with no history of depression.

  2. The CRHR1 gene reduces the risk for depressive symptoms among youths living in families undergoing high levels of economic hardship.

  3. CAL (show FBLIM1 Proteins) can regulate the anterograde trafficking, the internalization as well as the signaling of CRFR1 via modulating the post-translational modifications that the receptor undergoes at the Golgi apparatus.

  4. CRF-R1 activation by CRF and UCN inhibits the proliferation of SK-N-SH (N) cells and promotes neuronal-like differentiation.

  5. The results revealed that changes in depressive symptoms over time depended on both intervention group and genotypes (5-HTTLPR (show SLC6A4 Proteins) and CRHR1).

  6. CRHR1 gene SNP rs242941 polymorphism is associated with better response to systemic corticosteroid during acute exacerbation of asthma.

  7. Study provides data pointing out the critical role of corticotropin-releasing factor (show CRH Proteins), through CRF1R, in the positive reinforcing effects of morphine and in morphine-conducted behaviours

  8. The results suggested no association between the CRHR1 gene single nucleotide polymorphisms and infantile spasms in a Chinese population.

  9. the present study demonstrates that the expression of CRH/CRH (show CRH Proteins)-R1 in lesions of chronic plaque psoriasis is lower than that in psoriatic perilesional skin and normal control skin.

  10. The involvement of CRHR1 in ND.

Mouse (Murine) Corticotropin Releasing Hormone Receptor 1 (CRHR1) interaction partners

  1. Data suggest a physiologically relevant role for local corticotropin-releasing hormone (show CRH Proteins) signaling towards shaping the neuronal circuitry within the mouse olfactory bulb.

  2. A role was found for extra-hypothalamic CRF-R1 in stress-escalated alcohol drinking.

  3. This study demonstrated that an anatomical mechanism for sex-differences in the convergent modulation of ventrolateral medulla catecholaminergic neurons by CRF (show CRH Proteins) and glutamate (show GRIN1 Proteins).

  4. these results indicate that NPS-NPSR system may regulate locomotion together with the CRF1 system in SN.

  5. bladder smooth muscle contractility is unchanged by CsA (show HSPA9 Proteins); however, there are changes in the levels of the downstream transcription factors MEF-2 (show MYEF2 Proteins) and NFAT (show NFATC1 Proteins).

  6. The genetic disruption of the CRF1R pathway decreased the period of extinction in males and females suggesting that CRF (show CRH Proteins)/CRF1R is implicated in the duration of aversive memory.

  7. Anatomical and biochemical findings demonstrate that accumulation of Abeta (show APP Proteins) is significantly reduced in the brain of Alzheimer's disease model mice lacking CRFR1 providing support for a direct relationship between CRFR1 and Abeta (show APP Proteins) production pathways

  8. Results reveal the influences of early postnatal stress on the development of medial prefrontal cortex (mPFC) pyramidal neurons, and highlights CRF1 as a key molecule in modulating the detrimental stress effects on the structural organizations of mPFC

  9. it is shown that CRH (show CRH Proteins) and UCN upregulate galectin-1 (show LGALS1 Proteins) expression in Ishikawa cell line and macrophages and this effect is mediated through CRHR1.

  10. This study aims to investigate the cellular localization of CRF (show CRH Proteins) and UCNs in the ileum and to explore whether and how this cellular expression is altered in conditions of intestinal Schistosoma mansoni-induced inflammation.

Cow (Bovine) Corticotropin Releasing Hormone Receptor 1 (CRHR1) interaction partners

  1. These results suggest that a regulatory system exists in the bovine thyroid gland based on UCN, CRHR1 and CRHR2 and that UCN plays a role in the regulation of thyroid physiological functions through an autocrine/paracrine mechanism.

  2. CRHR1 and CRHR2 (show CRHR2 Proteins) are expressed in the bovine adrenal gland.

  3. results indicate that arginine vasopressin (show AVP Proteins) receptor V3 and corticotropin-releasing factor receptor 1 mRNAs are coordinately downregulated in the anterior pituitary during systemic inflammatory stress in cattle[AVP receptor V3 (show AVPR1B Proteins)]

Rhesus Monkey Corticotropin Releasing Hormone Receptor 1 (CRHR1) interaction partners

  1. The results of this study suggested that variation in CRHR1 may influence brain function before any childhood adversity and may be a diathesis for the interaction between CRHR1 genotypes and childhood trauma reported to affect human psychopathology

Xenopus laevis Corticotropin Releasing Hormone Receptor 1 (CRHR1) interaction partners

  1. CRF (show CRH Proteins) is expressed in tadpole tail, is up-regulated by environmental stressors, and is cytoprotective

CRHR1 Protein Profile

Protein Summary

This gene encodes a G-protein coupled receptor that binds neuropeptides of the corticotropin releasing hormone family that are major regulators of the hypothalamic-pituitary-adrenal pathway. The encoded protein is essential for the activation of signal transduction pathways that regulate diverse physiological processes including stress, reproduction, immune response and obesity. Alternative splicing results in multiple transcript variants, one of which represents a read-through transcript with the neighboring gene MGC57346.

Gene names and symbols associated with CRHR1

  • corticotropin releasing hormone receptor 1 (CRHR1)
  • corticotropin releasing hormone receptor 1 (Crhr1)
  • corticotropin releasing hormone receptor 1, gene 2 (crhr1.2)
  • CRF-R protein
  • CRF-R-1 protein
  • CRF-R1 protein
  • CRF1 protein
  • CRFR-1 protein
  • CRFR1 protein
  • CRH-R-1 protein
  • CRH-R1 protein
  • CRH-R1h protein
  • Crhr protein
  • crhr1 protein
  • crhr1-A protein
  • CRHR1f protein
  • CRHR1L protein

Protein level used designations for CRHR1

corticotropin releasing hormone receptor type I , corticotropin-releasing factor receptor 1 , corticotropin releasing hormone receptor 1 , corticotropin releasing hormone receptor variant 1e , corticotropin releasing hormone receptor variant 1g , corticotropin-releasing factor type 1 receptor , corticotropin-releasing hormone receptor 1 , seven transmembrane helix receptor , CRF 1 receptor , CRF-R-1 , CRF-R1 , CRF-R1alpha , CRFR-1 , CRH-R-1 , CRH-R1 , CRF-R , CRF1 , CRH-R 1 , corticotrophin releasing hormone receptor 1 , corticotropin releasing hormone 1 , corticotropin releasing factor receptor type 1 , corticotrophin-releasing factor type 1 alpha receptor

GENE ID SPECIES
397426 Sus scrofa
468283 Pan troglodytes
723971 Felis catus
100065598 Equus caballus
1394 Homo sapiens
12921 Mus musculus
58959 Rattus norvegicus
610380 Canis lupus familiaris
281716 Bos taurus
443025 Ovis aries
100302436 Oryctolagus cuniculus
374218 Gallus gallus
574095 Macaca mulatta
373580 Xenopus laevis
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