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Mitochondrial creatine (MtCK) kinase is responsible for the transfer of high energy phosphate from mitochondria to the cytosolic carrier, creatine. Additionally we are shipping Creatine Kinase, Mitochondrial 1, Ubiquitous Antibodies (18) and Creatine Kinase, Mitochondrial 1, Ubiquitous Kits (5) and many more products for this protein.
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Human CKMT1 Protein expressed in Escherichia coli (E. coli) - ABIN1046872
Haas, Korenfeld, Zhang, Perryman, Roman, Strauss: Isolation and characterization of the gene and cDNA encoding human mitochondrial creatine kinase. in The Journal of biological chemistry 1989
Hypothalamic plasticity of neuropeptide Y (show NPY Proteins) is lacking in brain-type creatine kinase double knockout mice with defective thermoregulation
mitochondrial creatine kinase (show CKMT2 Proteins) expression in hepatocellular carcinoma may be caused by hepatocarcinogenesis per se but not by loss of mitochondrial integrity, of which ASB9 (show ASB9 Proteins) could be a negative regulator
the knock-down of the mitochondrial creatine kinase (show CKMT2 Proteins)-1 (CKMT1) by RNA interference causes the dissipation of the mitochondrial membrane potential
UbCKmit was expressed selectively in neurons and localized in their mitochondria in dendrites, cell bodies
Data suggest that amyloid precursor protein (show APP Proteins) may regulate cellular energy levels and mitochondrial function via a direct interaction and stabilization of ubiquitous mitochondrial creatine kinase.
Mt-CK(-/-) on a C57BL/6 background do not develop LV hypertrophy or dysfunction even up to 1 year, and this may be explained by a compensatory increase in MM-CK activity and mitochondrial volume
Mitochondrial creatine kinase (show CKMT2 Proteins) CKMT1 (show CKMT1B Proteins) is necessary for survival of EVI1 (show MECOM Proteins)-expressing cells in subjects with EVI1 (show MECOM Proteins)-positive AML (show RUNX1 Proteins).
CKMT1 (show CKMT1B Proteins) is a key regulator of the permeability transition pore through a complex that is distinct from the classical permeability transition pore.
the knock-down of the mitochondrial creatine kinase (show CKMT2 Proteins)-1 (CKMT1 (show CKMT1B Proteins)) by RNA interference causes the dissipation of the mitochondrial membrane potential
ASB9 (show ASB9 Proteins) interacts with the creatine kinase system and negatively regulates cell growth.
MtCK, but not NDPK-D (show NME4 Proteins), shows some specificity in the nature of the lipids transferred and it is not active with phosphatidylcholine (show SGMS2 Proteins) alone
uMtCK (show CKMT1B Proteins) in prostate neoplasm cells (LNCaP) contributes to overproduction of reactive oxygen species, activation of Akt (show AKT1 Proteins) signaling pathway and more aggressive phenotypes including androgen independence development.
Mitochondrial creatine (MtCK) kinase is responsible for the transfer of high energy phosphate from mitochondria to the cytosolic carrier, creatine. It belongs to the creatine kinase isoenzyme family. It exists as two isoenzymes, sarcomeric MtCK and ubiquitous MtCK, encoded by separate genes. Mitochondrial creatine kinase occurs in two different oligomeric forms: dimers and octamers, in contrast to the exclusively dimeric cytosolic creatine kinase isoenzymes. Many malignant cancers with poor prognosis have shown overexpression of ubiquitous mitochondrial creatine kinase\; this may be related to high energy turnover and failure to eliminate cancer cells via apoptosis. Ubiquitous mitochondrial creatine kinase has 80% homology with the coding exons of sarcomeric mitochondrial creatine kinase. Two genes located near each other on chromosome 15 have been identified which encode identical mitochondrial creatine kinase proteins.
creatine kinase U-type, mitochondrial
, acidic-type mitochondrial creatine kinase
, ubiquitous mitochondrial creatine kinase
, creatine kinase, mitochondrial 1 (ubiquitous)
, creatine kinase, mitochondrial 1, ubiquitous