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Creatine Kinase, Mitochondrial 1A Proteins (CKMT1A)

Mitochondrial creatine (MtCK) kinase is responsible for the transfer of high energy phosphate from mitochondria to the cytosolic carrier, creatine. Additionally we are shipping CKMT1A Antibodies (39) and CKMT1A Kits (38) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
CKMT1A 548596 P12532
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Top CKMT1A Proteins at antibodies-online.com

Showing 4 out of 5 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag 100 μg Log in to see 7 to 8 Days
$319.00
Details
HOST_Baculovirus infected Insect Cells Human His tag 50 μg Log in to see 16 Days
$272.80
Details
HOST_Escherichia coli (E. coli) Human His tag,T7 tag 100 μg Log in to see 11 to 13 Days
$774.40
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   100 μg Log in to see 3 to 4 Days
$382.86
Details

CKMT1A Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,
,

Top referenced CKMT1A Proteins

  1. Human CKMT1A Protein expressed in Escherichia coli (E. coli) - ABIN1098309 : Stachowiak, Schlattner, Dolder, Wallimann: Oligomeric state and membrane binding behaviour of creatine kinase isoenzymes: implications for cellular function and mitochondrial structure. in Molecular and cellular biochemistry 1998 (PubMed)

More Proteins for Creatine Kinase, Mitochondrial 1A (CKMT1A) Interaction Partners

Human Creatine Kinase, Mitochondrial 1A (CKMT1A) interaction partners

  1. CKMT1 (show CKMT1B Proteins) is a key regulator of the permeability transition pore through a complex that is distinct from the classical permeability transition pore.

  2. the knock-down of the mitochondrial creatine kinase (show CKMT2 Proteins)-1 (CKMT1 (show CKMT1B Proteins)) by RNA interference causes the dissipation of the mitochondrial membrane potential

  3. ASB9 (show ASB9 Proteins) interacts with the creatine kinase system and negatively regulates cell growth.

  4. MtCK, but not NDPK-D (show NME4 Proteins), shows some specificity in the nature of the lipids transferred and it is not active with phosphatidylcholine (show SGMS2 Proteins) alone

  5. uMtCK (show CKMT1B Proteins) in prostate neoplasm cells (LNCaP) contributes to overproduction of reactive oxygen species, activation of Akt (show AKT1 Proteins) signaling pathway and more aggressive phenotypes including androgen independence development.

CKMT1A Protein Profile

Protein Summary

Mitochondrial creatine (MtCK) kinase is responsible for the transfer of high energy phosphate from mitochondria to the cytosolic carrier, creatine. It belongs to the creatine kinase isoenzyme family. It exists as two isoenzymes, sarcomeric MtCK and ubiquitous MtCK, encoded by separate genes. Mitochondrial creatine kinase occurs in two different oligomeric forms: dimers and octamers, in contrast to the exclusively dimeric cytosolic creatine kinase isoenzymes. Many malignant cancers with poor prognosis have shown overexpression of ubiquitous mitochondrial creatine kinase\; this may be related to high energy turnover and failure to eliminate cancer cells via apoptosis. Ubiquitous mitochondrial creatine kinase has 80% homology with the coding exons of sarcomeric mitochondrial creatine kinase. Two genes located near each other on chromosome 15 have been identified which encode identical mitochondrial creatine kinase proteins.

Gene names and symbols associated with CKMT1A

  • creatine kinase, mitochondrial 1A (LOC100228000)
  • creatine kinase, mitochondrial 1A (CKMT1A)
  • creatine kinase, mitochondrial 1A (Ckmt1a)
  • Ckmt1 protein

Protein level used designations for CKMT1A

creatine kinase, mitochondrial 1A , U-MtCK , acidic-type mitochondrial creatine kinase , creatine kinase U-type, mitochondrial , creatine kinase, ubiquitous mitochondrial , mia-CK , ubiquitous mitochondrial creatine kinase , creatine kinase, mitochondrial 1 (ubiquitous) , creatine kinase, mitochondrial 1, ubiquitous

GENE ID SPECIES
100228000 Taeniopygia guttata
374002 Gallus gallus
548596 Homo sapiens
100328683 Oryctolagus cuniculus
100725326 Cavia porcellus
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