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anti-Cryptochrome 1 (Photolyase-Like) (CRY1) Antibodies

CRY1 encodes a flavin adenine dinucleotide-binding protein that is a key component of the circadian core oscillator complex, which regulates the circadian clock. Additionally we are shipping CRY1 Kits (34) and CRY1 Proteins (5) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
CRY1 1407 Q16526
CRY1 12952 P97784
CRY1 299691 Q32Q86
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Top anti-CRY1 Antibodies at antibodies-online.com

Showing 10 out of 75 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Mouse Rabbit Un-conjugated WB Western blot analysis of extracts from 293T cells and Rat testis tissue using CRY1 antibody Western blot analysis of extracts from Mouse brain tissue using CRY1 antibody 0.1 mL Log in to see 6 to 8 Days
$308.00
Details
Human Rabbit Un-conjugated IHC (p), WB The anti-Cry1 N-term Pab (ABIN390079) is used in Western blot to detect Cry1 in placenta tissue lysate. Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. BC = breast carcinoma. HC = hepatocarcinoma 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated EIA, IHC (p), WB 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated WB 100 μg Log in to see 4 to 6 Days
$240.00
Details
Human Rabbit Un-conjugated IHC, WB Host: Rabbit  Target Name: CRY1  Sample Tissue: Hela Whole cell  Lane A:  Primary Antibody Lane B:  Primary Antibody + Blocking Peptide Primary Antibody Concentration: 1 µg/mL Peptide Concentration: 5 µg/mL Lysate Quantity: 41 µg/laneGel Concentration:.12 % 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Mouse Un-conjugated EIA, IF, IHC (p), WB 50 μg Log in to see 6 to 8 Days
$566.50
Details
Human Rabbit Un-conjugated IHC (p), WB Anti-CRY1 antibody IHC staining of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody  ABIN958965 concentration 5 ug/ml. 50 μg Log in to see 8 to 10 Days
$676.50
Details
Human Mouse Un-conjugated DB 50 μg Log in to see 7 to 9 Days
$285.71
Details
Human Mouse Un-conjugated WB CRY1 monoclonal antibody (M01), clone 4H4-1C4 Western Blot analysis of CRY1 expression in HeLa NE. Immunoperoxidase of monoclonal antibody to CRY1 on formalin-fixed paraffin-embedded human  (antibody concentration 10 µg/mL). 0.1 mg Log in to see 8 to 11 Days
$450.00
Details
Human Goat Un-conjugated IHC, ELISA, WB   100 μg Log in to see 8 to 10 Days
$969.83
Details

CRY1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Human , ,
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Mouse (Murine)


Rat (Rattus)


Top referenced anti-CRY1 Antibodies

  1. Human Polyclonal CRY1 Primary Antibody for EIA, IHC (p) - ABIN358613 : Griffin, Staknis, Weitz: Light-independent role of CRY1 and CRY2 in the mammalian circadian clock. in Science (New York, N.Y.) 1999 (PubMed)
    Show all 5 references for ABIN358613

  2. Human Polyclonal CRY1 Primary Antibody for IHC (p), WB - ABIN390079 : van der Horst, Muijtjens, Kobayashi, Takano, Kanno, Takao, de Wit, Verkerk, Eker, van Leenen, Buijs, Bootsma, Hoeijmakers, Yasui: Mammalian Cry1 and Cry2 are essential for maintenance of circadian rhythms. in Nature 1999 (PubMed)
    Show all 4 references for ABIN390079

  3. Mouse (Murine) Polyclonal CRY1 Primary Antibody for WB - ABIN783298 : Morioka, Sugimoto, Tokuhara, Dohi, Nakata: Noradrenaline induces clock gene Per1 mRNA expression in C6 glioma cells through beta(2)-adrenergic receptor coupled with protein kinase A - cAMP response element binding protein (PKA-CREB) and Src-tyrosine kinase - glycogen synthase kinase-3beta (Src-GSK in Journal of pharmacological sciences 2010 (PubMed)
    Show all 3 references for ABIN783298

More Antibodies against CRY1 Interaction Partners

Xenopus laevis Cryptochrome 1 (Photolyase-Like) (CRY1) interaction partners

  1. CRYs' C termini are essential for nuclear localization but not necessary for the suppression of CLOCK/BMAL1 (show ARNTL Antibodies) activation

  2. we investigated the structure/function relationships of Xenopus laevis CRY1 (xCRY1) and xCRY2 (show CRY2 Antibodies) in cultured cells

Rabbit Cryptochrome 1 (Photolyase-Like) (CRY1) interaction partners

  1. Cry1 is expressed in the olfactory bulb of newborn and juvenile rabbits.

Human Cryptochrome 1 (Photolyase-Like) (CRY1) interaction partners

  1. Altered CRY1 and CRY2 (show CRY2 Antibodies) expression patterns and the interplay with the genetic landscape in colon cancer cells may underlie phenotypic divergence.

  2. possible circadian rhythm in full-term placental expression

  3. Given the distinct characteristics of the C-terminal tails of the CRY1 and CRY2 (show CRY2 Antibodies) proteins, our study addresses a long-standing hypothesis that the ratio of these two CRY (show CRY2 Antibodies) molecules affects the clock period.

  4. Overexpression of CRY1 protects against the development of atherosclerosis via the TLR/NFkappaB pathway

  5. Collectively, these data show that KPNB1 (show KPNB1 Antibodies) is required for timely nuclear import of PER/CRY (show CRY2 Antibodies) in the negative feedback regulation of the circadian clock.

  6. these observations suggest a biologically plausible season-dependent association between SNPs at CRY1, CRY2 (show CRY2 Antibodies) and MTNR1B (show MTNR1B Antibodies) and glucose homeostasis.

  7. CRY1 and CRY2 (show CRY2 Antibodies) variants showed nominal association with the metabolic syndrome components, hypertension and triglyceride levels.

  8. In men undergoing acute total sleep deprivation, there was increased methylation in the promoter of CRY1 in adipose tissue compared with controls. Also decreased gene expression in skeletal muscle.

  9. SNPs in CRY1 were significantly associated with overall survival in Chinese hepatocellular carcinoma patients.

  10. Study reveals an interaction between a CRY1 variant and carbohydrate intake for glucose metabolism.

Mouse (Murine) Cryptochrome 1 (Photolyase-Like) (CRY1) interaction partners

  1. polyamines control the circadian period in cultured cells and animals by regulating the interaction between the core clock repressors PER2 (show PER2 Antibodies) and CRY1

  2. Data show that cryptochrome Cry1 and Cry2 (show CRY2 Antibodies) expression must be circadian and appropriately phased to support rhythms, and arginine vasopressin (AVP (show AVP Antibodies)) receptor signaling is required to impose circuit-level circadian function.

  3. Overexpression of CRY1 protects against the development of atherosclerosis via the TLR/NFkappaB pathway

  4. uncovered a novel biological role for CUL4A (show CUL4A Antibodies)-DDB1 (show DDB1 Antibodies)-CDT2 E3 ligase that regulates molecular circadian behaviors via promoting ubiquitination-dependent degradation of CRY1

  5. Data suggest that cryptochromes (Cry1 and Cry2 (show CRY2 Antibodies)) mediate periodic binding of Ck2b (show CSNK2B Antibodies) (casein kinase 2beta) to Bmal1 (aryl hydrocarbon receptor nuclear translocator-like (show ARNTL Antibodies) protein) and thus inhibit Bmal1 (show ARNTL Antibodies)-Ser90 phosphorylation by Ck2a (show CSNK2A1 Antibodies) (casein kinase 2alpha).

  6. demonstrate that genotoxic stress stimulates Cry1 phosphorylation and its deubiquitination by Herpes virus associated ubiquitin-specific protease (Hausp (show USP7 Antibodies), a.k.a Usp7 (show USP7 Antibodies)), stabilizing Cry1 and shifting circadian clock time

  7. Cry1/Cry2-deficient mice had significantly lower N6- methyladenosine methylation of RNA and lost the circadian rhythm of N6-methyladenosine levels in RNA.

  8. these results suggested that the overexpression of CRY1 inhibited sleep deprivation-induced vascular inflammation that might be associated with NF-kappaB (show NFKB1 Antibodies) and cAMP/PKA pathways.

  9. These results suggest that CRY1 fulfills its role as an essential circadian repressor by sequestering the C-terminal transactivation domain of BMAL1 (show ARNTL Antibodies) from coactivators.

  10. Report compression of daily activity time in Cry1 mutant mice.

Arabidopsis thaliana Cryptochrome 1 (Photolyase-Like) (CRY1) interaction partners

  1. These data illustrate that in vivo modulation by metabolites in the cellular environment may play an important role in cryptochrome signaling.

  2. For growth under a canopy, where blue light is diminished, CRY1 and CRY2 perceive this change and respond by directly contacting two bHLH transcription factors, PIF4 and PIF5.

  3. CRY1 represses auxin biosynthesis in response to elevated temperature through PIF4.

  4. CRY1 inhibits hypocotyl elongation in blue light through CNT1-mediated repression of the auxin/BR/GAresponsive gene expression.

  5. Reactive oxygen species formation results from cry1 activation and induces cell death in insect cell cultures.

  6. The study shows that ATP binding and aspartate protonation enhance photoinduced electron transfer in plant CRY1.

  7. photoreduction-deficient Trp (show TBPL1 Antibodies)-triad mutations of CRY1 remained physiologically and biochemically active in Arabidopsis plants.

  8. Based on the loss of degradation of cry2 (show CRY2 Antibodies) after prolonged darkness and loss of reversibility of photoactivated cry1 by a pulse of green light, we estimate the in vivo half-lives of the signaling states of cry1 and cry2 (show CRY2 Antibodies) to be in the range of 5 and 16 min.

  9. Data indicate that the green light (GL) opposition of red light (RL) responses persists in phyA, phyB, cry1cry2 and phot2 mutants, and the response requires phot1 and NPH3.

  10. Perception of light by phyA, cry1 or phyB activates ROC1; this in turn reduces the intensity of brassinosteroid signalling and fine-tunes seedling de-etiolation.

CRY1 Antigen Profile

Protein Summary

This gene encodes a flavin adenine dinucleotide-binding protein that is a key component of the circadian core oscillator complex, which regulates the circadian clock. The encoded protein is widely conserved across plants and animals. Loss of the related gene in mouse results in a shortened circadian cycle in complete darkness.

Gene names and symbols associated with CRY1

  • cryptochrome 1 (photolyase-like) (cry1-A) antibody
  • cryptochrome 1 (photolyase-like) (CRY1) antibody
  • cryptochrome 1 (photolyase-like) (cry1) antibody
  • cryptochrome 1 (CRY1) antibody
  • LOC100384475 (siu50817b) antibody
  • cryptochrome 1 (cry1) antibody
  • cryptochrome 1 (photolyase-like) (LOC100223409) antibody
  • cryptochrome 1 (photolyase-like) (LOC100347047) antibody
  • cryptochrome 1 (photolyase-like) (Cry1) antibody
  • cryptochrome-1 (CRY1) antibody
  • ATCRY1 antibody
  • AU020726 antibody
  • AU021000 antibody
  • BLU1 antibody
  • BLUE LIGHT UNINHIBITED 1 antibody
  • CRY1 antibody
  • cry1-A antibody
  • cry2 antibody
  • cryptochrome 1 antibody
  • CRYPTOCHROME 1 APOPROTEIN (BLUE LIGHT PHOTORECEPTOR antibody
  • ELONGATED HYPOCOTYL 4 antibody
  • HY4 antibody
  • OOP2 antibody
  • OUT OF PHASE 2 antibody
  • Phll1 antibody
  • T3H13.14 antibody
  • T3H13_14 antibody
  • xCRY1 antibody

Protein level used designations for CRY1

cryptochrome 1 (photolyase-like) , cryptochrome 2 (photolyase-like) , cryptochrome 1 , cryptochrome-1-like , cryptochrome-1

GENE ID SPECIES
394398 Xenopus laevis
452205 Pan troglodytes
550065 Xenopus (Silurana) tropicalis
100008577 Meleagris gallopavo
100034165 Equus caballus
100384475 Zea mays
100500923 Bombyx mori
100223409 Taeniopygia guttata
100347047 Oryctolagus cuniculus
100408307 Callithrix jacchus
100431934 Pongo abelii
100484388 Ailuropoda melanoleuca
100582392 Nomascus leucogenys
1407 Homo sapiens
12952 Mus musculus
299691 Rattus norvegicus
100714070 Cavia porcellus
100520380 Sus scrofa
374093 Gallus gallus
474528 Canis lupus familiaris
535947 Bos taurus
443263 Ovis aries
826470 Arabidopsis thaliana
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