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Crystallin, alpha A (CRYAA) ELISA Kits

Crystallins are separated into two classes taxon-specific, or enzyme, and ubiquitous. Additionally we are shipping Crystallin, alpha A Antibodies (89) and Crystallin, alpha A Proteins (67) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
CRYAA 1409 P02489
CRYAA 24273 P24623
CRYAA 12954 P24622
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Top Crystallin, alpha A ELISA Kits at antibodies-online.com

Showing 7 out of 14 products:

Catalog No. Reactivity Sensitivity Range Quantity Supplier Delivery Price Details
Human 7.8 pg/ml 31.2-2000 pg/mL 96 Tests Log in to see 11 to 13 Days
$910.56
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Rat 9.75 pg/ml 39-2500 pg/mL 96 Tests Log in to see 11 to 13 Days
$910.56
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Mouse
96 Tests Log in to see 11 to 13 Days
$875.60
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Cow
96 Tests Log in to see 11 to 13 Days
$1,029.60
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Pig
96 Tests Log in to see 11 to 13 Days
$1,029.60
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Chicken
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$1,095.60
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Dog
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$1,095.60
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More ELISA Kits for Crystallin, alpha A Interaction Partners

Xenopus laevis Crystallin, alpha A (CRYAA) interaction partners

  1. The ontogeny and localization of the alphaA-crystallin and betaB1-crystallin (show CRYBB1 ELISA Kits) during embryonic lens development and regeneration indicated a different development program, although they have identical origins, the ectoderm.

Zebrafish Crystallin, alpha A (CRYAA) interaction partners

  1. The normal development observed in alphaA-crystallin deficient zebrafish embryos may reflect similarly non-essential roles for this protein in the early stages of both zebrafish and mammalian lens development.

  2. Fndings establish that the C-terminal extension of alphaA crystallin can be either 3D domain swapped or non-3D domain swapped.

  3. alphaA-crystallin (HSPB4) is expressed during development.

Human Crystallin, alpha A (CRYAA) interaction partners

  1. isomerization of Asp (show ASIP ELISA Kits) might disrupt the higher order polymeric state of alpha-crystallin, resulting in decreased solubility and function, ultimately contributing to lens protein impairment and cataract formation with aging

  2. Collectively, these studies show that FGF signaling up-regulates expression of alphaA-crystallin both directly and indirectly via up-regulation of c-Maf (show MAF ELISA Kits).

  3. Similar to wild type alphaA- and alphaB-crystallins, the deamidated mutants showed strong interaction with betaA3-crystallin (show CRYBA1 ELISA Kits).

  4. Identification of a novel mutation in CRYAA associated with congenital cataracts.

  5. A novel disease-causing mutation, c.246_248delCGC (p.117delR), of the CRYAA gene has been identified in a Chinese family with autosomal-type perinuclear congenital cataracts.

  6. The loss of interactions between alpha A-crystallin N-terminal mutants and alpha B-crystallin (show CRYAB ELISA Kits) signifies quaternary structural alterations due to mutation in the arginine residues.

  7. CpG islands hypermethylation of alphaA-crystallin gene may be involved in nuclear cataract formation after pars (show EPRS ELISA Kits) plana vitrectomy.

  8. Genetic variations of KCNAB1 (show KCNAB1 ELISA Kits) and CRYAA are associated with age-related nuclear cataract.

  9. A 19-residue fragment of human alpha-crystallin A not only exhibits chaperone-like activity toward gamma D-crystallin (show CRYGD ELISA Kits) but also forms a stable complex with it.

  10. Knockout of alphaA-crystallin inhibited pathologic neovascularization through the VEGF (show VEGFA ELISA Kits) and VEGFR2 (show KDR ELISA Kits) signaling pathways both in vitro and in vivo.

Cow (Bovine) Crystallin, alpha A (CRYAA) interaction partners

  1. For moderate O-GlcNAcylation on bovine crystalline alpha, the preferred amino acids were Pro > Ala > Gly at position -2, Ala > Thr (show TRH ELISA Kits) >Val > Lys (show LYZ ELISA Kits) > Pro at position -1, and Ala > Gly > Arg > Glu (show DCTN1 ELISA Kits) at position +2.

  2. Alpha-crystallin, in the presence of the sorbitol dehydrogenase (SDH (show SORD ELISA Kits)) pyridine cofactor NAD(H), can exert a remarkable chaperone action by favoring the recovery of the enzyme activity from chemically denaturated SDH (show SDS ELISA Kits) up to 77%.

  3. Conserved triad in alphaA-crystallin contributes to stability of higher order oligomers but is not essential for formation of tetramers.

  4. Mass spectrometry analysis and a database search identified carbamylated proteins originating from alphaA-crystallin, betaB2- and gammaS-(betaS)-crystallins.

Mouse (Murine) Crystallin, alpha A (CRYAA) interaction partners

  1. Collectively, these studies show that FGF signaling up-regulates expression of alphaA-crystallin both directly and indirectly via up-regulation of c-Maf (show MAF ELISA Kits).

  2. Knockout of alphaA-crystallin inhibited pathologic neovascularization through the VEGF (show VEGFA ELISA Kits) and VEGFR2 (show KDR ELISA Kits) signaling pathways both in vitro and in vivo.

  3. p53 (show TP53 ELISA Kits) can regulate lens differentiation by controlling expression of the differentiation genes coding for the lens crystallins.

  4. Alpha A crystallin is a moonlighting protein that functions as a heat shock protein as well as a lens crystalline.

  5. alphaA-crystallin may protect against geographic atrophy.

  6. alphaA and alphaB regulate caspase-3 (show CASP3 ELISA Kits) and Bax (show BAX ELISA Kits) in vitro and in vivo to regulate lens differentiation.

  7. these findings show that mutation of alphaA-crystallin induces activation of the UPR during cataract formation.

  8. Hydroimidazolone modification of human alphaA-crystallin: Effect on the chaperone function and protein refolding ability.

  9. Methionine oxidation of alpha-crystallin in combination with loss of MsrA (show MSR1 ELISA Kits) repair causes loss of alpha-crystallin chaperone function.

  10. mouse lens epithelial cell progression through the cell cycle is significantly affected by expression of alphaA and alphaB-crystallin (show CRYAB ELISA Kits)

Rabbit Crystallin, alpha A (CRYAA) interaction partners

Crystallin, alpha A (CRYAA) Antigen Profile

Antigen Summary

Crystallins are separated into two classes taxon-specific, or enzyme, and ubiquitous. The latter class constitutes the major proteins of vertebrate eye lens and maintains the transparency and refractive index of the lens. Since lens central fiber cells lose their nuclei during development, these crystallins are made and then retained throughout life, making them extremely stable proteins. Mammalian lens crystallins are divided into alpha, beta, and gamma families\; beta and gamma crystallins are also considered as a superfamily. Alpha and beta families are further divided into acidic and basic groups. Seven protein regions exist in crystallins: four homologous motifs, a connecting peptide, and N- and C-terminal extensions. Alpha crystallins are composed of two gene products: alpha-A and alpha-B, for acidic and basic, respectively. Alpha crystallins can be induced by heat shock and are members of the small heat shock protein (sHSP also known as the HSP20) family. They act as molecular chaperones although they do not renature proteins and release them in the fashion of a true chaperone\; instead they hold them in large soluble aggregates. Post-translational modifications decrease the ability to chaperone. These heterogeneous aggregates consist of 30-40 subunits\; the alpha-A and alpha-B subunits have a 3:1 ratio, respectively. Two additional functions of alpha crystallins are an autokinase activity and participation in the intracellular architecture. Alpha-A and alpha-B gene products are differentially expressed\; alpha-A is preferentially restricted to the lens and alpha-B is expressed widely in many tissues and organs. Defects in this gene cause autosomal dominant congenital cataract (ADCC).

Gene names and symbols associated with Crystallin, alpha A (CRYAA) ELISA Kits

  • crystallin, alpha A (cryaa) antibody
  • crystallin, alpha A (CRYAA) antibody
  • alphaA-crystallin (CpipJ_CPIJ005646) antibody
  • alpha-A-crystallin protein (alpha-a-crystallin) antibody
  • alpha-crystallin A chain-like (LOC100384978) antibody
  • alpha-crystallin A chain-like (LOC100460863) antibody
  • crystallin, alpha A (Cryaa) antibody
  • Acry-1 antibody
  • AI323437 antibody
  • alpha-a-crystallin antibody
  • Crya-1 antibody
  • Crya1 antibody
  • CRYAA antibody
  • cryaa-A antibody
  • CTRCT9 antibody
  • DAcry-1 antibody
  • HSPB4 antibody
  • lop18 antibody
  • wu:fc06h04 antibody
  • zgc:92036 antibody

Protein level used designations for Crystallin, alpha A (CRYAA) ELISA Kits

crystallin, alpha A , alphaA-crystallin , [a]A-crystallin , alpha-crystallin A chain , hspb4 , alpha-A-crystallin protein , alpha-crystallin A chain-like , crystallin, alpha-1 , heat shock protein beta-4 , human alphaA-crystallin (CRYA1) , Crystallin, alpha polypeptide A , crystallin, alpha 1 , lens opacity 18 , alpha-A-crystallin , alpha A crystallin , Alpha-crystallin A chain

GENE ID SPECIES
378668 Xenopus laevis
458589 Pan troglodytes
791110 Ornithorhynchus anatinus
6037267 Culex quinquefasciatus
100000769 Danio rerio
100049490 Oryzias latipes
100384978 Callithrix jacchus
100460863 Pongo abelii
1409 Homo sapiens
24273 Rattus norvegicus
281718 Bos taurus
12954 Mus musculus
101083874 Felis catus
418546 Gallus gallus
487786 Canis lupus familiaris
100135506 Cavia porcellus
100051134 Equus caballus
100009294 Oryctolagus cuniculus
497275 Ovis aries
722370 Macaca mulatta
101520527 Ochotona princeps
101828899 Mesocricetus auratus
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