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Cullin 5 Proteins (CUL5)

neuropeptide arginine vasopressin receptor\; may have a role in the central nervous system [RGD, Feb 2006].. Additionally we are shipping Cullin 5 Antibodies (61) and Cullin 5 Kits (10) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
CUL5 8065 Q93034
CUL5 75717 Q9D5V5
CUL5 64624 Q9JJ31
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Top Cullin 5 Proteins at

Showing 5 out of 5 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific pu... 1 mg Log in to see 39 to 44 Days
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific pu... 1 mg Log in to see 39 to 44 Days
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
HOST_Human Human Un-conjugated   20 μg Log in to see 19 Days

CUL5 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
Mouse (Murine)

Rat (Rattus)

More Proteins for Cullin 5 (CUL5) Interaction Partners

Fruit Fly (Drosophila melanogaster) Cullin 5 (CUL5) interaction partners

  1. cullin-5 and cullin-2 (show CUL2 Proteins) play a role in the development of neuromuscular junction and the female germ line of Drosophila

  2. Data show that the follicular epithelium that normally encapsulates single germ line cysts develops aberrantly in cul-5 mutant.

  3. cul-5 plays multiple roles in cell fate specification and synapse formation during Drosophila development.

Human Cullin 5 (CUL5) interaction partners

  1. These results provide important information on the assembly of the Vif (show BTG1 Proteins)-CUL5-E3 ubiquitin ligase (show MUL1 Proteins) and identify a new viV binding interface with CBF-beta (show CBFB Proteins) at the C-terminus of HIV-1 Vif (show BTG1 Proteins).

  2. Data indicate that cell surface adhesion molecules VCAM-1 (show VCAM1 Proteins) and P-selectin (show SELP Proteins) play some roles in mechanical stretch-induced HL-60 cell adhesion to mouse common carotid arteries.

  3. N-terminal mutants of HIV-1 vif (show BTG1 Proteins) that demonstrated reduced Cul5 binding were also unable to degrade APOBEC3G (show APOBEC3G Proteins) as well as APOBEC3F (show APOBEC3F Proteins).

  4. A tumor suppressor gene, CUL5, is identified as a direct target of miR-7 (show LILRB1 Proteins) in hepatocellular carcinoma.

  5. Silencing CUL5 reduced cellular sensitivity to three distinct HSP90 (show HSP90 Proteins) inhibitors, across four cancer types driven by different protein kinases.

  6. In the absence of CBFbeta (show CBFB Proteins), Vif (show BTG1 Proteins) does not bind Cul5, thus preventing the assembly of the E3 ligase complex.

  7. CBF-beta (show CBFB Proteins) is critical for the formation of the Vif (show BTG1 Proteins)-ElonginB/ElonginC-Cul5 core E3 ubiquitin ligase (show MUL1 Proteins) complex.

  8. data reveal the structural basis for Vif (show BTG1 Proteins) hijacking of the CBF-beta (show CBFB Proteins) and CUL5 E3 ligase complex, laying a foundation for rational design of novel anti-HIV drugs

  9. ASB9 (show ASB9 Proteins) is unstable alone but forms a stable ternary complex with EloBC that binds with high affinity to the Cullin 5 N-terminal domain.

  10. crystal structure shows interaction between SOCS2 (show SOCS2 Proteins)-elongin BC and Cullin-5

Mouse (Murine) Cullin 5 (CUL5) interaction partners

  1. Our results show that endogenous Cul5 suppresses epithelial cell transformation by several pathways, including inhibition of Src (show SRC Proteins)-Cas (show CTNND1 Proteins)-induced ruffling through SOCS6 (show SOCS6 Proteins)

  2. The expression of cullin5 on retinal cells and reduction in the percentage of dead retinal cells induced by L-glutamate (show GRIN1 Proteins) suggest that cullin5 has neuroprotective properties in retinal cells.

  3. SOCS (show CISH Proteins) box acts as an independent binding domain capable of recruiting elonginBC and cullin5 to promote E3 ligase formation.

  4. The role of Cul5 is to degrade disabled homolog 1 (Dab1 (show DAB1 Proteins)) and thus control neuron migration speed and neuron insertion at the top of the cortical plate.

  5. These results suggest that, when Src (show SRC Proteins) is activated by mutation or physiological mechanisms, its effects are limited by Culllin 5, which downregulates active Src (show SRC Proteins) and its phosphorylated substrates.

  6. data imply the existence of two distinct subclasses of SOCS (show CISH Proteins) proteins with a high affinity for Cullin5, the E3 ligase scaffold, possibly reflecting complete dependence upon ubiquitination for suppression of cytokine signalling

Rabbit Cullin 5 (CUL5) interaction partners

  1. The study results suggest that VACM-1 may regulate endothelial AQP1 concentration both in vivo and in vitro.

Caenorhabditis elegans (C. elegans) Cullin 5 (CUL5) interaction partners

  1. oocyte maturation from pachytene exit and MPK-1 (show MAPK1 Proteins) activation are redundantly controlled by the RBX-2-CUL-5- and RBX-1 (show RBX1 Proteins)-CUL-2 (show CUL2 Proteins)-based complexes.

Cullin 5 (CUL5) Protein Profile

Protein Summary

neuropeptide arginine vasopressin receptor\; may have a role in the central nervous system

Gene names and symbols associated with Cullin 5 Proteins (CUL5)

  • cullin 5a (cul5a)
  • cullin 5 (cul5)
  • Cullin-5 (Cul-5)
  • cullin 5 (CUL5)
  • cullin 5 (Cul5)
  • Protein CUL-5 (cul-5)
  • 4921514I20Rik protein
  • 8430423K24Rik protein
  • AI852817 protein
  • C030032G03Rik protein
  • C330021I08Rik protein
  • CG1401 protein
  • cul-5 protein
  • Cul5 protein
  • Cullin-5 protein
  • Cullin5 protein
  • Cullin 5 protein
  • Dmel\\CG1401 protein
  • VACM-1 protein
  • VACM1 protein
  • wu:fd17d09 protein
  • wu:fi20h12 protein
  • Xcullin5 protein
  • xx:11fd17d09 protein
  • zgc:66185 protein

Protein level used designations for Cullin 5 Proteins (CUL5)

Vasopressin-activated calcium-mobilizing receptor (VACM-1) , cullin 5 , CG1401-PA , Cul-5-PA , cullin , Vasopressin-activated calcium-mobilizing receptor-1 , CUL-5 , Cullin-5 (vasopressin-activated calcium-mobilizing receptor-1) , cullin-5 , vasopressin-activated calcium-mobilizing receptor 1 , vasopressin-activated calcium-mobilizing receptor protein , VACM-1 , vasopressin-activated calcium-mobilizing protein

327215 Danio rerio
100126611 Xenopus laevis
43434 Drosophila melanogaster
100061726 Equus caballus
466773 Pan troglodytes
780297 Xenopus (Silurana) tropicalis
8065 Homo sapiens
75717 Mus musculus
64624 Rattus norvegicus
100009207 Oryctolagus cuniculus
418969 Gallus gallus
489422 Canis lupus familiaris
510331 Bos taurus
100172507 Pongo abelii
179413 Caenorhabditis elegans
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