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CUX2 encodes a protein which contains three CUT domains and a homeodomain\; both domains are DNA-binding motifs. Additionally we are shipping CUX2 Proteins (3) and many more products for this protein.
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Dog (Canine) Polyclonal CUX2 Primary Antibody for WB - ABIN2783056
Gingras, Cases, Krasilnikova, Bérubé, Nepveu: Biochemical characterization of the mammalian Cux2 protein. in Gene 2005
results suggest that the persistent expression of CUX2 in postmitotic neurons contributes to the maintenance of genome integrity through its stimulation of oxidative DNA damage repair.
CUX2 inhibited HNF6 (show ONECUT1 Antibodies) transcriptional regulation of the sex-specific gene promoters CYP2C11 and CYP2C12, blocking HNF6 (show ONECUT1 Antibodies) repression of CYP2C11 and HNF6 (show ONECUT1 Antibodies) activation of CYP2C12.
Results suggest that Cux2 expression reflects hippocampal neurogenesis and identifies non-self-renewing neural progenitors in the subgranular zone of the dentate gyrus
Results suggest that by their differential effects on basal and apical dendrites, Cux1 (show CUX1 Antibodies) and Cux2 can promote the integration of layer II-III neurons in the intracortical networks in highly specific ways
Cux2-positive radial glial cells generate diverse subtypes of neocortical projection neurons and macroglia
Cux2 activity plays an important role for ongoing neurogenesis in the olfactory epithelium
The downregulation of CUX2 in male liver at puberty contributes to the developmental changes establishing adult patterns of sex-specific gene expression.
Cux2 is expressed and may participate in development of a specific subtype of myelinated TrkA (show NTRK1 Antibodies)(+) nociceptors.
Cux1 (show CUX1 Antibodies) and Cux2 play critical roles in dendritogenesis via subclass-specific mechanisms of synapse regulation that contribute to the establishment of cognitive circuits.
Cux-2 mRNA expression is found in the embryonic subventricular zone of the cerebral cortex, overlapping with bromodeoxyuridine-positive dividing precursors, but it is not expressed in the ventricular zone.
This gene encodes a protein which contains three CUT domains and a homeodomain\; both domains are DNA-binding motifs. A similar gene, whose gene product possesses different DNA-binding activities, is located on chromosome on chromosome 7. Two pseudogenes of this gene have been identified on chromosomes 10 and 4.
homeobox protein cut-like 2
, homeobox protein cux-2
, cut-like 2
, homeobox protein Cux-2