You are viewing an incomplete version of our website. Please click to reload the website as full version.

anti-Cyclic Nucleotide Gated Channel beta 3 (CNGB3) Antibodies

CNGB3 encodes the beta subunit of a cyclic nucleotide-gated ion channel. Additionally we are shipping CNGB3 Proteins (7) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
CNGB3 54714 Q9NQW8
CNGB3 30952 Q9JJZ9
Anti-Rat CNGB3 CNGB3 500418  
How to order from antibodies-online
  • +1 877 302 8632
  • +1 888 205 9894 (toll-free)
  • Order online
  • orders@antibodies-online.com

Top anti-CNGB3 Antibodies at antibodies-online.com

Showing 10 out of 24 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated EIA, WB CNGB3 Antibody (N-term) western blot analysis in MDA-MB435 cell line lysates (35µg/lane).This demonstrates the CNGB3 antibody detected the CNGB3 protein (arrow). 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated WB CNGB3 Antibody (N-term) (ABIN656636) western blot analysis in MDA-MB435 cell line lysates (35 µg/lane). This demonstrates the CNGB3 antibody detected the CNGB3 protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated WB 400 μL Log in to see 6 Days
$457.14
Details
Human Rabbit PE ELISA, WB   200 μL Log in to see 8 to 10 Days
$969.83
Details
Human Rabbit Un-conjugated ELISA   200 μL Log in to see 8 to 10 Days
$713.17
Details
Human Rabbit Un-conjugated ELISA, WB   200 μL Log in to see 11 to 16 Days
$532.71
Details
Human Rabbit Un-conjugated WB   50 μg Log in to see 8 to 10 Days
$551.83
Details
Human Rabbit APC ELISA, WB   200 μL Log in to see 16 Days
$710.29
Details
Human Rabbit FITC ELISA, WB   200 μL Log in to see 16 Days
$710.29
Details
Human Rabbit HRP ELISA, WB   200 μL Log in to see 16 Days
$710.29
Details

CNGB3 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Human , ,


, , , , ,
Mouse (Murine)


Top referenced anti-CNGB3 Antibodies

  1. Human Polyclonal CNGB3 Primary Antibody for EIA, WB - ABIN951585 : Komáromy, Alexander, Rowlan, Garcia, Chiodo, Kaya, Tanaka, Acland, Hauswirth, Aguirre: Gene therapy rescues cone function in congenital achromatopsia. in Human molecular genetics 2010 (PubMed)
    Show all 4 references for ABIN951585

More Antibodies against CNGB3 Interaction Partners

Human Cyclic Nucleotide Gated Channel beta 3 (CNGB3) interaction partners

  1. Eight different mutations were detected in the CNGB3 gene in achromatopsia, including five novel mutations: two splice site mutations, one nonsense substitution, and two frame-shift mutations.

  2. Genetic testing revealed a common homozygous mutation in CNGB3 in 5 patients with complete achromatopsia and heterozygous mutations in CNGA3 (show CNGA3 Antibodies) in 2 patients with incomplete achromatopsia.

  3. Genetic testing performed at Carver lab at the University of Iowa confirmed a diagnosis of achromatopsia with identical mutations in the CNGB3 gene.

  4. The majority (n = 12) of patients were either homozygotes or compound heterozygotes for known achromatopsia alleles, two in CNGB3 (p.T383fsX and p.T296YfsX9) and three in CNGA3 (show CNGA3 Antibodies) (p.R283Q, p.R427C and p.L527R).

  5. Data found pathogenic DNA variants in the genes RP1 (show STK19 Antibodies), USH2A (show USH2A Antibodies), CNGB3, NMNAT1 (show NMNAT1 Antibodies), CHM (show CHM Antibodies), and ABCA4 (show ABCA4 Antibodies), responsible for retinitis pigmentosa, Usher syndrome, achromatopsia, Leber congenital amaurosis, choroideremia (show CHM Antibodies), or recessive Stargardt/cone-rod dystrophy cases.

  6. Achromatopsia associated F525N and T383fsX mutations in the CNGB3 subunit of cone photoreceptor cyclic nucleotide-gated (CNG (show CNGA1 Antibodies)) channels increases susceptibility to cell death in photoreceptor-derived cells.

  7. Subretinal administration of rAAV5-hCNGB3 with a long version of the red cone opsin (show RHO Antibodies) promoter in younger animals led to a stable therapeutic effect for at least 33 months.

  8. Genetic analysis of two Pakistani families with retinal disease enabled the establishment of the correct diagnosis of achromatopsia. Two novel mutations were identified in CNGA3 (show CNGA3 Antibodies) and CNGB3 that are both specifically expressed in cone photoreceptors.

  9. down-regulation of CNGA3 (show CNGA3 Antibodies) contributes to the pathogenic mechanism by which CNGB3 mutations lead to human cone disease.

  10. NH2- and COOH-terminal calmodulin-binding sites in CNGB3 are functionally important for regulation of cyclic nucleotide-gated channel activity

Mouse (Murine) Cyclic Nucleotide Gated Channel beta 3 (CNGB3) interaction partners

  1. CNGB3 regulates cone light response kinetics and the channel structural flexibility.

  2. This work investigated the functional modulation of cone CNG (show CNGA1 Antibodies) channel by exploring the channel-interacting proteins.

  3. Cone CNG (show CNGA1 Antibodies) channel is a heterotetrameric complex likely at a stoichiometry of three CNGA3 (show CNGA3 Antibodies) and one CNGB3.

  4. RDS (show PRPH2 Antibodies) does not interact with the cone CNG (show CNGA1 Antibodies).

  5. The heteromeric cyclic nucleotide-gated channel adopts a 3A:1B stoichiometry

CNGB3 Antigen Profile

Protein Summary

This gene encodes the beta subunit of a cyclic nucleotide-gated ion channel. The encoded beta subunit appears to play a role in modulation of channel function in cone photoreceptors. This heterotetrameric channel is necessary for sensory transduction, and mutations in this gene have been associated with achromatopsia 3, progressive cone dystrophy, and juvenile macular degeneration, also known as Stargardt Disease.

Gene names and symbols associated with CNGB3

  • cyclic nucleotide gated channel beta 3 (CNGB3) antibody
  • cyclic nucleotide gated channel beta 3 (cngb3) antibody
  • cyclic nucleotide gated channel beta 3 (Cngb3) antibody
  • ACHM1 antibody
  • CCNC2 antibody
  • Cng6 antibody
  • Cngbeta2 antibody
  • RGD1565364 antibody

Protein level used designations for CNGB3

cyclic nucleotide gated channel beta 3 , cyclic nucleotide-gated cation channel beta-3 , CNG channel beta-3 , cone photoreceptor cGMP-gated cation channel beta-subunit , cyclic nucleotide-gated cation channel modulatory subunit , cone photoreceptor cGMP-gated channel subunit beta , cyclic nucleotide gated channel beta 6 , cyclic nucleotide-gated channel beta-3 , cyclic nucleotide-gated channel subunit CNG6 , cyclic nucleotide gated channel beta subunit

GENE ID SPECIES
464272 Pan troglodytes
519225 Bos taurus
562675 Danio rerio
100029201 Monodelphis domestica
100233165 Ovis aries
54714 Homo sapiens
30952 Mus musculus
403554 Canis lupus familiaris
428367 Gallus gallus
500418 Rattus norvegicus
Selected quality suppliers for anti-CNGB3 (CNGB3) Antibodies
Did you look for something else?