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Transcriptional regulator which participates in regulating the pre-mRNA splicing process. Additionally we are shipping Cyclin L1 Antibodies (51) and Cyclin L1 Kits (15) and many more products for this protein.
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CCNL1 (show MCM2 Proteins) is the target gene of miR (show MLXIP Proteins)-199b-5p.
Data indicate that if the newborn carried a risk allele rs900400 near LEKR/CCNL1 (show MCM2 Proteins), the impact of stress on birth size was stronger.
birth weight lowering effect of the C-allele of rs900400 located near LEKR1 and CCNL1 (show MCM2 Proteins) was replicated in the Danish population. Furthermore the C-allele was associated with increased insulin (show INS Proteins) response following oral glucose stimulation
Data show low birth weight in Asian Indians is not due to variation near CCNL1 (show MCM2 Proteins)/ADCY5 (show ADCY5 Proteins), but variant ADCY5 (show ADCY5 Proteins) is associated with elevated glucose/decreased insulin (show INS Proteins) response which suggests a common genetic cause of low birth weight and risk of type 2 diabetes.
These data demonstrate that there is a fine balance between CCNL1 (show MCM2 Proteins) and TIMP1 (show TIMP1 Proteins), which may contribute to breast cancer development.
Our results suggest that a genetic variant of ccnl1 (show MCM2 Proteins) leads to symmetric growth restriction from early pregnancy onward
Cyclin L1 amplification is associated with uterine cervical carcinoma.
variants in ADCY5 (show ADCY5 Proteins) and near CCNL1 (show MCM2 Proteins) are associated with fetal growth and birth weight
Cyclin L has been shown to associate with the PITSLRE (show CDK11A Proteins) kinase and is involved in pre-mRNA processing (show PRPF39 Proteins).
Our results indicate that CCNL1 (show MCM2 Proteins) plays a critical role in the loco-regional progression of HNSCC and may serve as an indicator for occult advanced tumour stages.
Transcriptional regulator which participates in regulating the pre-mRNA splicing process. Seems to be involved in the regulation of RNA polymerase II (pol II). Functions in association with cyclin-dependent kinases (CDKs) and has a role in the second step of splicing. May be a candidate proto-oncogene in head and neck squamous cell carcinomas (HNSCC). Inhibited by the CDK-specific inhibitor p21.
, cyclin L ania-6a
, cyclin L gamma
, cyclin ania-6a
, cyclin Ania-6a
, minichromosome maintenance complex component 2