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anti-Cyclin T2 (CCNT2) Antibodies

The protein encoded by CCNT2 belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Additionally we are shipping Cyclin T2 Kits (20) and Cyclin T2 Proteins (4) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
CCNT2 905 O60583
CCNT2 72949  
CCNT2 304758  
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Top anti-Cyclin T2 Antibodies at antibodies-online.com

Showing 10 out of 37 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated ELISA, WB Western blot using Anti-Cyclin T2 (Rabbit) is shown to detect two major bands (arrowheads) corresponding to human Cyclin T2a and T2b as indicated. Approximately 33 ?g of a HeLa whole cell lysate was separated by 4-20% Tris Glycine SDS-PAGE. After blocking the membrane with 5% BLOTTO (p/n B501-0500) in PBS, the membrane was probed for overnight at 4° C with the primary antibody diluted to 1:500 in 5% BLOTTO in PBS. The membrane was washed and reacted with a 1:10,000 dilution of IRDye™800 conjugated Gt-a-Rabbit IgG [H&L] (611-132-122) for 45 min at room temperature (800 nm channel, green). Molecular weight estimation was made by comparison to prestained MW markers indicated at the right (700 nm channel, red). IRDye™800 fluorescence image was captured using the Odyssey® Infrared Imaging System developed by LI-COR. IRDye is a trademark of LI-COR, Inc. Other detection systems will yield similar results. 100 μL Log in to see 2 to 3 Days
$369.00
Details
Human Mouse Un-conjugated DB, WB 50 μg Log in to see 7 to 9 Days
$285.71
Details
Human Rabbit Un-conjugated ICC, IHC (p), WB   100 μL Log in to see 8 to 10 Days
$507.83
Details
Human Rabbit Un-conjugated ICC, IF, IHC (p), WB WB Image Sample (30 ug of whole cell lysate) A: Hep G2 , 7.5% SDS PAGE antibody diluted at 1:1000 ICC/IF Image Immunofluorescence analysis of paraformaldehyde-fixed A431, using cyclin T2, antibody at 1:200 dilution. 100 μL Log in to see 2 to 3 Days
$358.60
Details
Human Mouse Un-conjugated ELISA, WB CCNT2 monoclonal antibody (M03), clone 1H3. Western Blot analysis of CCNT2 expression in Jurkat. Detection limit for recombinant GST tagged CCNT2 is 0.3 ng/ml as a capture antibody. 100 μg Log in to see 9 Days
$430.00
Details
Human Rabbit Un-conjugated IHC (fp), IF, WB 100 μL Log in to see 6 to 11 Days
$485.71
Details
Human Rabbit Un-conjugated EIA, WB   0.1 mL Log in to see 6 to 8 Days
$500.50
Details
Human Rabbit Alexa Fluor 488 IF (p)   100 μL Log in to see 14 to 21 Days
$357.50
Details
Human Rabbit Alexa Fluor 647 IF (p)   100 μL Log in to see 14 to 21 Days
$357.50
Details
Human Rabbit Alexa Fluor 350 IF (p)   100 μL Log in to see 14 to 21 Days
$357.50
Details

CCNT2 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Rat (Rattus) ,


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More Antibodies against Cyclin T2 Interaction Partners

Human Cyclin T2 (CCNT2) interaction partners

  1. the release of P-TEFb (show CCNT1 Antibodies) from the 7SK snRNP (show LSM2 Antibodies) led to increased synthesis of HEXIM1 (show HEXIM1 Antibodies) but not HEXIM2 (show HEXIM2 Antibodies)

  2. interaction with pRb (show RB1 Antibodies)

  3. CycT2 not only contains two domains that target rna polymerase II but this substrate recognition is necessary for its transcriptional activity via DNA

  4. Data strengthen the hypothesis that Cyclin T2a plays a role in muscle differentiation, and propose PKNalpha (show PKN1 Antibodies) as a novel partner of Cyclin T2a in this process.

  5. The results establish that cdk9 (show CDK9 Antibodies)/cyclin T2a-mediated coactivation of MyoD (show MYOD1 Antibodies) depends on serine 37 phosphorylation.

  6. These results suggest that acetylation of CDK9 (show CDK9 Antibodies) is an important posttranslational modification that is involved in regulating P-TEFb (show CCNT1 Antibodies) transcriptional elongation function.

  7. TAF7 interacts with the transcription factors, TFIIH and P-TEFb, resulting in the inhibition of their Pol II CTD kinase activities

  8. The tripartite protein-RNA complex formation between Hexim (show HEXIM1 Antibodies), Cyclin T (show CCNT1 Antibodies) and 7SK snRNA, was analyzed.

Mouse (Murine) Cyclin T2 (CCNT2) interaction partners

  1. both isoforms of Cyclin T2 are able to activate the myogenic program but Cyclin T2b has a predominant role, in particular during the latest stages.

  2. miR (show MLXIP Antibodies)-15a inhibited muscle differentiation at least in part by targeting Ccnt2; roles in spermatogenesis.

  3. activation of MyoD (show MYOD1 Antibodies)-dependent transcription by cdk9 (show CDK9 Antibodies)/cyclin T2

  4. despite numerous matings of heterozygous mice, we observed no CycT2(-/-) embryos, pups, or adult mice. This early lethality could have resulted from decreased expression of critical genes

Cyclin T2 (CCNT2) Antigen Profile

Protein Summary

The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin and its kinase partner CDK9 were found to be subunits of the transcription elongation factor p-TEFb. The p-TEFb complex containing this cyclin was reported to interact with, and act as a negative regulator of human immunodeficiency virus type 1 (HIV-1) Tat protein. A pseudogene of this gene is found on chromosome 1. Alternate splicing results in multiple transcript variants.

Gene names and symbols associated with anti-Cyclin T2 (CCNT2) Antibodies

  • cyclin T2 (CCNT2) antibody
  • cyclin T2b (ccnt2b) antibody
  • cyclin T2a (ccnt2a) antibody
  • cyclin T2 (ccnt2) antibody
  • cyclin T2 (Ccnt2) antibody
  • 2900041I18Rik antibody
  • C81304 antibody
  • CCNT2 antibody
  • cycT antibody
  • CycT2 antibody
  • CycT2b antibody
  • fb16c03 antibody
  • MGC81210 antibody
  • wu:fb16c03 antibody
  • wu:fi17h07 antibody
  • wu:fj68b10 antibody
  • zgc:55357 antibody
  • zgc:55690 antibody

Protein level used designations for anti-Cyclin T2 (CCNT2) Antibodies

cyclin T2 , cyclin-T2 , cyclin-T2-like , SDS-stable vimentin-bound DNA fragment HEF42VIM22 , cyclin T2a , cyclin T2b , subunit of positive elongation transcription factor b

GENE ID SPECIES
100050510 Equus caballus
321464 Danio rerio
327568 Danio rerio
447439 Xenopus laevis
470546 Pan troglodytes
476126 Canis lupus familiaris
100349398 Oryctolagus cuniculus
100412841 Callithrix jacchus
100446291 Pongo abelii
100488125 Xenopus (Silurana) tropicalis
100011986 Monodelphis domestica
100552048 Anolis carolinensis
100599933 Nomascus leucogenys
905 Homo sapiens
424289 Gallus gallus
521089 Bos taurus
72949 Mus musculus
304758 Rattus norvegicus
101106913 Ovis aries
Selected quality suppliers for anti-Cyclin T2 (CCNT2) Antibodies
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