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Cyclin-Dependent Kinase 14 (CDK14) ELISA Kits

Serine/threonine-protein kinase involved in the control of the eukaryotic cell cycle, whose activity is controlled by an associated cyclin. Additionally we are shipping CDK14 Antibodies (75) and CDK14 Proteins (12) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
Anti-Human CDK14 CDK14 5218 O94921
Anti-Mouse CDK14 CDK14 18647 O35495
Anti-Rat CDK14 CDK14 362316  
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More ELISA Kits for CDK14 Interaction Partners

Human Cyclin-Dependent Kinase 14 (CDK14) interaction partners

  1. Knockdown of PFTK1 inhibited the proliferation and invasion of pancreatic cancer cells as well as the EMT (show ITK ELISA Kits) progress by suppressing the PI3K (show PIK3CA ELISA Kits)/Akt (show AKT1 ELISA Kits) signaling pathway.

  2. PFTK1 overexpression promoted proliferation, migration and invasion of gastric cancer cells, while PFTK1 knockdown led to the opposite results.

  3. Knockdown of PFTK1 increases E-cadherin (show CDH1 ELISA Kits) expression, decreases vimentin (show VIM ELISA Kits) expression and inhibits migration of glioma cells.

  4. Up-regulated PFTK1 might promote breast cancer progression.

  5. Cigarette smoke down regulates CDK14 levels and impairs Wnt (show WNT2 ELISA Kits) signaling.

  6. findings indicate that brain PP-1I associates with and is regulated by the associated protein kinases C-TAK1 (show MARK3 ELISA Kits) and PFTK1

  7. binding of CCNY (show CCNY ELISA Kits) to 14-3-3 (show YWHAQ ELISA Kits) significantly enhanced the association between CCNY (show CCNY ELISA Kits) and CDK14

  8. Human cyclin Y (CCNY (show CCNY ELISA Kits)) is a phosphoprotein in vivo and phosphorylation of CCNY (show CCNY ELISA Kits) by CDK14 triggers its ubiquitination and degradation.

  9. in patients with oesophageal squamous cell carcinoma 5-year overall survival rate was poorer in patients positive for PFTK1 than those with negative expression; uni- and multivariate analyses identified PFTK1 as an independent marker of prognosis

  10. Taken together, our data propose a novel, oncogene (show RAB1A ELISA Kits)-tumor suppressor interplay, where oncogenic PFTK1 confers HCC (show FAM126A ELISA Kits) cell motility through inactivating the actin-binding motile suppressing function of TAGLN2 (show TAGLN2 ELISA Kits) via phosphorylation.

Mouse (Murine) Cyclin-Dependent Kinase 14 (CDK14) interaction partners

  1. Cigarette smoke down regulates CDK14 levels and impairs Wnt (show WNT2 ELISA Kits) signaling.

  2. may be a key regulator for thyrotropin-releasing hormone (TRH (show TRH ELISA Kits)) action in the cerebellum through the NO-cGMP pathway

CDK14 Antigen Profile

Antigen Summary

Serine/threonine-protein kinase involved in the control of the eukaryotic cell cycle, whose activity is controlled by an associated cyclin. Acts as a cell-cycle regulator of Wnt signaling pathway during G2/M phase by mediating the phosphorylation of LRP6 at 'Ser-1490', leading to the activation of the Wnt signaling pathway. Acts as a regulator of cell cycle progression and cell proliferation via its interaction with CCDN3. Phosphorylates RB1 in vitro, however the relevance of such result remains to be confirmed in vivo. May also play a role in meiosis, neuron differentiation and may indirectly act as a negative regulator of insulin-responsive glucose transport.

Gene names and symbols associated with CDK14

  • cyclin-dependent kinase 14 (CDK14) antibody
  • PFTAIRE protein kinase 1 (PFTK1) antibody
  • cyclin-dependent kinase 14 (Cdk14) antibody
  • cyclin-dependent kinase 14 (cdk14) antibody
  • mKIAA0834 antibody
  • pftaire1 antibody
  • pftk1 antibody

Protein level used designations for CDK14

PFTAIRE protein kinase 1 , cell division protein kinase 14 , hPFTAIRE1 , serine/threonine-protein kinase PFTAIRE-1 , Cell division protein kinase 14

GENE ID SPECIES
463522 Pan troglodytes
703442 Macaca mulatta
100137460 Papio anubis
100173505 Pongo abelii
5218 Homo sapiens
18647 Mus musculus
362316 Rattus norvegicus
100328634 Oryctolagus cuniculus
420546 Gallus gallus
475223 Canis lupus familiaris
100515962 Sus scrofa
784403 Bos taurus
101424147 Dasypus novemcinctus
100391008 Callithrix jacchus
444781 Xenopus laevis
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