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anti-Cyclin-Dependent Kinase 5, Regulatory Subunit 2 (p39) (CDK5R2) Antibodies

The protein encoded by CDK5R2 is a neuron-specific activator of CDK5 kinase. Additionally we are shipping Cyclin-Dependent Kinase 5, Regulatory Subunit 2 (p39) Kits (1) and and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
Anti-Rat CDK5R2 CDK5R2 501164  
CDK5R2 8941 Q13319
CDK5R2 12570 O35926
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Top anti-Cyclin-Dependent Kinase 5, Regulatory Subunit 2 (p39) Antibodies at antibodies-online.com

Showing 10 out of 27 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated ELISA, WB Western blot analysis of extracts from HuvEc cells, using CDK5R2 Antibody. The lane on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Rabbit Un-conjugated IHC (p), WB 0.1 mg Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated WB WB Suggested Anti-CDK5R2 AntibodyTitration: 1.0 µg/mL  Positive Control: NCI-H226 Whole Cell 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated ELISA, WB 100 μL Log in to see 8 to 10 Days
$478.50
Details
Human Rabbit Un-conjugated ELISA, WB 100 μg Log in to see 11 to 16 Days
$412.86
Details
Human Rabbit PE IHC, ELISA   200 μL Log in to see 8 to 10 Days
$969.83
Details
Human Rabbit Un-conjugated IHC, WB   0.1 mL Log in to see 5 to 7 Days
$452.81
Details
Human Rabbit Un-conjugated WB   50 μg Log in to see 8 to 10 Days
$551.83
Details
Human Rabbit Un-conjugated ELISA   200 μL Log in to see 8 to 10 Days
$713.17
Details
Human Rabbit Un-conjugated ICC   100 μL Log in to see 8 to 10 Days
$375.83
Details

CDK5R2 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Human , ,
,

, , , , ,
Mouse (Murine)


Top referenced anti-Cyclin-Dependent Kinase 5, Regulatory Subunit 2 (p39) Antibodies

  1. Human Polyclonal CDK5R2 Primary Antibody for ELISA, WB - ABIN1533863 : Hillier, Graves, Fulton, Fulton, Pepin, Minx, Wagner-McPherson, Layman, Wylie, Sekhon, Becker, Fewell, Delehaunty, Miner, Nash, Kremitzki, Oddy, Du, Sun, Bradshaw-Cordum, Ali, Carter, Cordes, Harris et al.: Generation and annotation of the DNA sequences of human chromosomes 2 and 4. ... in Nature 2005 (PubMed)

More Antibodies against Cyclin-Dependent Kinase 5, Regulatory Subunit 2 (p39) Interaction Partners

Human Cyclin-Dependent Kinase 5, Regulatory Subunit 2 (p39) (CDK5R2) interaction partners

  1. p39 (show JUN Antibodies) is essential for recruiting scaffolding protein muskelin (show MKLN1 Antibodies) to stress fibers.

  2. Structural basis for the different stability and activity between the Cdk5 (show CDK5 Antibodies) complexes with p35 (show ANXA1 Antibodies) and p39 (show JUN Antibodies) activators.

  3. Hepatocellular carcinoma patients with lower p39 (show JUN Antibodies) expression had poorer overall survival rate than that with high expression.

  4. both proteasomal degradation and calpain cleavage of p35 (show ANXA1 Antibodies) and p39 (show JUN Antibodies) are stimulated by membrane association, which is in turn mediated via myristoylation of their p10 (show S100A10 Antibodies) regions.

  5. Our data suggest that neurotoxic insults lead to calpain-mediated conversion of p39 (show JUN Antibodies) to p29 (show PRTN3 Antibodies), which might contribute to deregulation of Cdk5 (show CDK5 Antibodies)

  6. role of the CDK5 (show CDK5 Antibodies) molecular complex in the genetic etiology of early-onset Alzheimer disease; a yet unknown functional variant in CDK5 (show CDK5 Antibodies) or in a nearby gene might lead to increased susceptibility for early-onset Alzheimer disease

Mouse (Murine) Cyclin-Dependent Kinase 5, Regulatory Subunit 2 (p39) (CDK5R2) interaction partners

  1. These data suggest p35 (show CDK5R1 Antibodies) and p39 (show ATP6V0D1 Antibodies) have specific and overlapping roles in oligodendrocyte development, some of which may be independent of Cdk5 (show CDK5 Antibodies) activation.

  2. it was found that Tyr (show TYR Antibodies)-15 phosphorylation occurred only on monomeric Cdk5 (show CDK5 Antibodies), and the coexpression of activators, p35/p25 (show CDK5R1 Antibodies), p39 (show ATP6V0D1 Antibodies), or Cyclin I (show CCNI Antibodies), inhibited the phosphorylation.

  3. Structural basis for the different stability and activity between the Cdk5 (show CDK5 Antibodies) complexes with p35 (show CDK5R1 Antibodies) and p39 (show ATP6V0D1 Antibodies) activators.

  4. Data indicate that p39 (show ATP6V0D1 Antibodies) is selectively up-regulated in oligodendroglia (OL) during differentiation along with elevated Cdk5 (show CDK5 Antibodies) activity.

  5. A set of REST target genes, including Cdk5r2, is important for beta cell survival.

  6. The alternating p39 (show ATP6V0D1 Antibodies) parasagittal band pattern may reflect a role for p39 (show ATP6V0D1 Antibodies) or Cdk5 (show CDK5 Antibodies)/p39 (show ATP6V0D1 Antibodies) in the functional compartmentation of the cerebellum.

  7. Data show that both p35 (show CDK5R1 Antibodies) and p39 (show ATP6V0D1 Antibodies) are expressed in insulin (show INS Antibodies)-secreting beta cells, where they exhibit individual subcellular distributions and associate with membranous organelles of different densities.

  8. These findings demonstrate that Cdk5 (show CDK5 Antibodies), p35 (show CDK5R1 Antibodies), and p39 (show ATP6V0D1 Antibodies) are endogenously expressed in NG108-15 cells, exhibit distinct subcellular localizations, and that both Cdk5 (show CDK5 Antibodies)/p35 (show CDK5R1 Antibodies) and Cdk5 (show CDK5 Antibodies)/p39 (show ATP6V0D1 Antibodies) are central in formation of functional synapses.

  9. The differential nuclear accumulation of p39 (show ATP6V0D1 Antibodies) and p35 (show CDK5R1 Antibodies) suggests their segregated functions, p35 (show CDK5R1 Antibodies)-Cdk5 (show CDK5 Antibodies) in the cytoplasm and p39 (show ATP6V0D1 Antibodies)-Cdk5 (show CDK5 Antibodies) in the nucleus.

Cyclin-Dependent Kinase 5, Regulatory Subunit 2 (p39) (CDK5R2) Antigen Profile

Protein Summary

The protein encoded by this gene is a neuron-specific activator of CDK5 kinase. It associates with CDK5 to form an active kinase. This protein and neuron-specific CDK5 activator CDK5R1/p39NCK5A both share limited similarity to cyclins, and thus may define a distinct family of cyclin-dependent kinase activating proteins.

Gene names and symbols associated with CDK5R2

  • cyclin-dependent kinase 5, regulatory subunit 2 (p39) (CDK5R2) antibody
  • cyclin-dependent kinase 5, regulatory subunit 2 (p39) (Cdk5r2) antibody
  • cyclin-dependent kinase 5, regulatory subunit 2a (p39) (cdk5r2a) antibody
  • cyclin-dependent kinase 5, regulatory subunit 2 (p39) (cdk5r2) antibody
  • B230310J22Rik antibody
  • cdk5r2 antibody
  • MGC115331 antibody
  • NCK5AI antibody
  • p39 antibody
  • p39nck5ai antibody
  • RGD1562530 antibody
  • wu:fj48b05 antibody
  • zgc:110126 antibody

Protein level used designations for CDK5R2

cyclin-dependent kinase 5, regulatory subunit 2 (p39) , cyclin-dependent kinase 5 activator 2 , cyclin-dependent kinase 5, regulatory subunit 2-like , p39 , fj48b05 , CDK5 activator 2 , cyclin-dependent kinase 5 activator isoform p39i , cyclin-dependent kinase 5 regulatory subunit 2 , neuronal CDK5 activator isoform , p39I

GENE ID SPECIES
459953 Pan troglodytes
488529 Canis lupus familiaris
501164 Rattus norvegicus
528533 Bos taurus
550231 Danio rerio
734425 Xenopus laevis
8941 Homo sapiens
12570 Mus musculus
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