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Cyclin-Dependent Kinase 5, Regulatory Subunit 2 (p39) (CDK5R2) ELISA Kits

The protein encoded by CDK5R2 is a neuron-specific activator of CDK5 kinase. Additionally we are shipping Cyclin-Dependent Kinase 5, Regulatory Subunit 2 (p39) Antibodies (26) and and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
Anti-Rat CDK5R2 CDK5R2 501164  
CDK5R2 8941 Q13319
Anti-Mouse CDK5R2 CDK5R2 12570 O35926
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Top Cyclin-Dependent Kinase 5, Regulatory Subunit 2 (p39) ELISA Kits at antibodies-online.com

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Catalog No. Reactivity Sensitivity Range Quantity Supplier Delivery Price Details
Human
96 Tests Log in to see 6 Days
$528.57
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More ELISA Kits for Cyclin-Dependent Kinase 5, Regulatory Subunit 2 (p39) Interaction Partners

Human Cyclin-Dependent Kinase 5, Regulatory Subunit 2 (p39) (CDK5R2) interaction partners

  1. p39 (show JUN ELISA Kits) is essential for recruiting scaffolding protein muskelin (show MKLN1 ELISA Kits) to stress fibers.

  2. Structural basis for the different stability and activity between the Cdk5 (show CDK5 ELISA Kits) complexes with p35 (show ANXA1 ELISA Kits) and p39 (show JUN ELISA Kits) activators.

  3. Hepatocellular carcinoma patients with lower p39 (show JUN ELISA Kits) expression had poorer overall survival rate than that with high expression.

  4. both proteasomal degradation and calpain cleavage of p35 (show ANXA1 ELISA Kits) and p39 (show JUN ELISA Kits) are stimulated by membrane association, which is in turn mediated via myristoylation of their p10 (show S100A10 ELISA Kits) regions.

  5. Our data suggest that neurotoxic insults lead to calpain-mediated conversion of p39 (show JUN ELISA Kits) to p29 (show PRTN3 ELISA Kits), which might contribute to deregulation of Cdk5 (show CDK5 ELISA Kits)

  6. role of the CDK5 (show CDK5 ELISA Kits) molecular complex in the genetic etiology of early-onset Alzheimer disease; a yet unknown functional variant in CDK5 (show CDK5 ELISA Kits) or in a nearby gene might lead to increased susceptibility for early-onset Alzheimer disease

Mouse (Murine) Cyclin-Dependent Kinase 5, Regulatory Subunit 2 (p39) (CDK5R2) interaction partners

  1. These data suggest p35 (show CDK5R1 ELISA Kits) and p39 (show ATP6V0D1 ELISA Kits) have specific and overlapping roles in oligodendrocyte development, some of which may be independent of Cdk5 (show CDK5 ELISA Kits) activation.

  2. it was found that Tyr (show TYR ELISA Kits)-15 phosphorylation occurred only on monomeric Cdk5 (show CDK5 ELISA Kits), and the coexpression of activators, p35/p25 (show CDK5R1 ELISA Kits), p39 (show ATP6V0D1 ELISA Kits), or Cyclin I (show CCNI ELISA Kits), inhibited the phosphorylation.

  3. Structural basis for the different stability and activity between the Cdk5 (show CDK5 ELISA Kits) complexes with p35 (show CDK5R1 ELISA Kits) and p39 (show ATP6V0D1 ELISA Kits) activators.

  4. Data indicate that p39 (show ATP6V0D1 ELISA Kits) is selectively up-regulated in oligodendroglia (OL) during differentiation along with elevated Cdk5 (show CDK5 ELISA Kits) activity.

  5. A set of REST target genes, including Cdk5r2, is important for beta cell survival.

  6. The alternating p39 (show ATP6V0D1 ELISA Kits) parasagittal band pattern may reflect a role for p39 (show ATP6V0D1 ELISA Kits) or Cdk5 (show CDK5 ELISA Kits)/p39 (show ATP6V0D1 ELISA Kits) in the functional compartmentation of the cerebellum.

  7. Data show that both p35 (show CDK5R1 ELISA Kits) and p39 (show ATP6V0D1 ELISA Kits) are expressed in insulin (show INS ELISA Kits)-secreting beta cells, where they exhibit individual subcellular distributions and associate with membranous organelles of different densities.

  8. These findings demonstrate that Cdk5 (show CDK5 ELISA Kits), p35 (show CDK5R1 ELISA Kits), and p39 (show ATP6V0D1 ELISA Kits) are endogenously expressed in NG108-15 cells, exhibit distinct subcellular localizations, and that both Cdk5 (show CDK5 ELISA Kits)/p35 (show CDK5R1 ELISA Kits) and Cdk5 (show CDK5 ELISA Kits)/p39 (show ATP6V0D1 ELISA Kits) are central in formation of functional synapses.

  9. The differential nuclear accumulation of p39 (show ATP6V0D1 ELISA Kits) and p35 (show CDK5R1 ELISA Kits) suggests their segregated functions, p35 (show CDK5R1 ELISA Kits)-Cdk5 (show CDK5 ELISA Kits) in the cytoplasm and p39 (show ATP6V0D1 ELISA Kits)-Cdk5 (show CDK5 ELISA Kits) in the nucleus.

Cyclin-Dependent Kinase 5, Regulatory Subunit 2 (p39) (CDK5R2) Antigen Profile

Antigen Summary

The protein encoded by this gene is a neuron-specific activator of CDK5 kinase. It associates with CDK5 to form an active kinase. This protein and neuron-specific CDK5 activator CDK5R1/p39NCK5A both share limited similarity to cyclins, and thus may define a distinct family of cyclin-dependent kinase activating proteins.

Gene names and symbols associated with CDK5R2

  • cyclin-dependent kinase 5, regulatory subunit 2 (p39) (CDK5R2) antibody
  • cyclin-dependent kinase 5, regulatory subunit 2 (p39) (Cdk5r2) antibody
  • cyclin-dependent kinase 5, regulatory subunit 2a (p39) (cdk5r2a) antibody
  • cyclin-dependent kinase 5, regulatory subunit 2 (p39) (cdk5r2) antibody
  • B230310J22Rik antibody
  • cdk5r2 antibody
  • MGC115331 antibody
  • NCK5AI antibody
  • p39 antibody
  • p39nck5ai antibody
  • RGD1562530 antibody
  • wu:fj48b05 antibody
  • zgc:110126 antibody

Protein level used designations for CDK5R2

cyclin-dependent kinase 5, regulatory subunit 2 (p39) , cyclin-dependent kinase 5 activator 2 , cyclin-dependent kinase 5, regulatory subunit 2-like , p39 , fj48b05 , CDK5 activator 2 , cyclin-dependent kinase 5 activator isoform p39i , cyclin-dependent kinase 5 regulatory subunit 2 , neuronal CDK5 activator isoform , p39I

GENE ID SPECIES
459953 Pan troglodytes
488529 Canis lupus familiaris
501164 Rattus norvegicus
528533 Bos taurus
550231 Danio rerio
734425 Xenopus laevis
8941 Homo sapiens
12570 Mus musculus
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