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Cystatin C Proteins (CST3)

The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Additionally we are shipping Cystatin C Antibodies (405) and Cystatin C Kits (116) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
CST3 1471 P01034
CST3 13010 P21460
CST3 25307 P14841
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Top Cystatin C Proteins at antibodies-online.com

Showing 10 out of 85 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag Cystatin C (CST3) (AA 27-146), (full length) protein (His tag) 50 μg Log in to see 9 to 11 Days
$217.80
Details
HOST_Human Cells Human His tag 10 μg Log in to see 16 Days
$250.80
Details
HOST_Human Cells Mouse His tag 10 μg Log in to see 16 Days
$250.80
Details
HOST_Human Cells Rat His tag 10 μg Log in to see 16 Days
$250.80
Details
HOST_Escherichia coli (E. coli) Human His tag 50 μg Log in to see 7 to 8 Days
$407.00
Details
HOST_Human Cells Human Un-conjugated 10 μg Log in to see 16 Days
$250.80
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_HEK-293 Human Un-conjugated 50 μg Log in to see 2 to 3 Days
$756.00
Details
HOST_Escherichia coli (E. coli) Dog His tag 50 μg Log in to see 9 to 11 Days
$550.00
Details

CST3 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , , , , , ,
,
Mouse (Murine) ,

Rat (Rattus) , ,

Top referenced Cystatin C Proteins

  1. Rat (Rattus) CST3 Protein expressed in Human Cells - ABIN2009079 : Janowski, Kozak, Jankowska, Grzonka, Grubb, Abrahamson, Jaskolski: Human cystatin C, an amyloidogenic protein, dimerizes through three-dimensional domain swapping. in Nature structural biology 2001 (PubMed)
    Show all 5 references for ABIN2009079

  2. Human CST3 Protein expressed in Human Cells - ABIN2002853 : Kos, Stabuc, Cimerman, Brünner: Serum cystatin C, a new marker of glomerular filtration rate, is increased during malignant progression. in Clinical chemistry 1999 (PubMed)
    Show all 5 references for ABIN2002853

  3. Mouse (Murine) CST3 Protein expressed in Human Cells - ABIN2007555 : Fricker, Wiesli, Brändle, Schwegler, Schmid: Impact of thyroid dysfunction on serum cystatin C. in Kidney international 2003 (PubMed)
    Show all 5 references for ABIN2007555

  4. Human CST3 Protein expressed in Human Cells - ABIN2002851 : Kaeser, Herzig, Coomaraswamy, Kilger, Selenica, Winkler, Staufenbiel, Levy, Grubb, Jucker: Cystatin C modulates cerebral beta-amyloidosis. in Nature genetics 2007 (PubMed)
    Show all 5 references for ABIN2002851

  5. Human CST3 Protein expressed in Escherichia coli (E. coli) - ABIN1046896 : Saitoh, Sabatini, Eddy, Shows, Azen, Isemura, Sanada: The human cystatin C gene (CST3) is a member of the cystatin gene family which is localized on chromosome 20. in Biochemical and biophysical research communications 1989 (PubMed)
    Show all 2 references for ABIN1046896

  6. Human CST3 Protein expressed in Escherichia coli (E. coli) - ABIN1098585 : Liu: Evaluation of serum cystatin C for diagnosis of acute rejection after renal transplantation. in Transplantation proceedings 2012 (PubMed)

More Proteins for Cystatin C (CST3) Interaction Partners

Human Cystatin C (CST3) interaction partners

  1. findings suggest that both NGAL (show LCN2 Proteins) and CysC are very sensitive markers that reflect renal impairment in newly diagnosed patients with multiple myeloma.

  2. Cystatin C demonstrated incremental benefit in the prediction of response to cardiac resynchronization therapy.

  3. the A25T polymorphism does not cause a significant reduction in Cystatin C secretion, but instead predisposes the protein to be cleaved at an alternative signal sequence cleavage site.

  4. Cystatin C-based eGFR (show EGFR Proteins) is a superior prognostic parameter to creatinine-based eGFR (show EGFR Proteins) in post-endovascular therapy peripheral artery disease patients.

  5. Cystatin C expression was significantly downregulated in breast cancer cells with p53 (show TP53 Proteins) mutations, and decreased cystatin C expression was associated with poor prognosis of breast cancer.

  6. the role of the cystatin C signal peptide in pathogenesis of AD and AMD (show AMD1 Proteins)

  7. Results revealed that cystatin C deposition in Hereditary Cystatin C Amyloid Angiopathy is always spatially associated with arteries, i.e. parenchymal focal deposits were never seen in areas with no arteries

  8. Serum cystatin C reflects angiographic coronary collateralization in patients with stable coronary artery disease, and cystatin C >/= 0.97 mg/L indicates a great risk of poor coronary collaterals.

  9. the level of Cys-C in CSF should not be considered as a biomarker of ALS. Cys-C in serum may be useful as an indicator of the severity of disease and site of symptoms onset although the specificity of serum Cys-C levels in ALS was not significant.

  10. Postoperative serum Cys (show DNAJC5 Proteins) C appears to be a more specific and sensitive biomarker for NGAL (show LCN2 Proteins)-positive AKI resulting from cardiopulmonary bypass surgery in infants undergoing cardiac surgery.

Mouse (Murine) Cystatin C (CST3) interaction partners

  1. Data (including data from studies in mutant mice) suggest that up-regulation of Cst3, as observed in plasma of mice with type 2 diabetes, down-regulates insulin (show INS Proteins) signaling and promotes endoplasmic reticulum stress in hepatocytes but not in myotubes.

  2. Cystatin C is a potential pathogenic signal triggering neurodegeneration in multiple system atrophy.

  3. The neuroprotective activity of CysC against Amyotrophic lateral sclerosis-linked mutant Cu/Zn-superoxide dismutase (SOD1 (show SOD1 Proteins))-mediated toxicity.

  4. an important role for macrophages, DC, and ROS (show ROS1 Proteins) in diseases associated with the protease inhibitory activity or amyloidogenic properties of cystatin C.

  5. APP (show APP Proteins) expression stimulates NSPC proliferation; this effect is mediated via an increase in cystatin C secretion

  6. Cystatin C, a protein targeted to the classical secretory pathway by its signal peptide sequence, is secreted by primary neurons in at least 9 different cystatin C glycoforms associated with exosomes.

  7. The lack of cystatin C enhances Collagen-induced arthritis and primarily affects in vivo priming of the immune system

  8. Inflammation causes downregulation of cystatin C expression in dendritic cells and reduces serum CstC levels.

  9. Data show that the absence of cystatin C reduced epithelial cell apoptosis but increased proliferation in skin.

  10. Data show that cystatin C effectively rescues cystatin B (show CSTB Proteins) loss-of-function mutation, facilitating the reversal of pathophysiological changes and suggesting a novel therapeutic intervention for patients with neurodegenerative disorders.

Pig (Porcine) Cystatin C (CST3) interaction partners

  1. CST3 may be required to remodel endometrial and placental tissues for close apposition between maternal and fetal vasculatures and to facilitate transplacental transport of gases, micronutrients (amino acids, glucose), and macromolecules (proteins).

Rabbit Cystatin C (CST3) interaction partners

  1. Increased production of cystatin C in osteoarthritis synovium does not alleviate synovitis or cartilage pathology.

Cow (Bovine) Cystatin C (CST3) interaction partners

  1. Cystatin C in milk basic protein (MBP (show MBP Proteins)) is suggested as one of the factors inhibiting bone resorption

Cystatin C (CST3) Protein Profile

Protein Summary

The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins and the kininogens. The type 2 cystatin proteins are a class of cysteine proteinase inhibitors found in a variety of human fluids and secretions, where they appear to provide protective functions. The cystatin locus on chromosome 20 contains the majority of the type 2 cystatin genes and pseudogenes. This gene is located in the cystatin locus and encodes the most abundant extracellular inhibitor of cysteine proteases, which is found in high concentrations in biological fluids and is expressed in virtually all organs of the body. A mutation in this gene has been associated with amyloid angiopathy. Expression of this protein in vascular wall smooth muscle cells is severely reduced in both atherosclerotic and aneurysmal aortic lesions, establishing its role in vascular disease.

Gene names and symbols associated with Cystatin C Proteins (CST3)

  • cystatin C (CST3)
  • cystatin C (cst3)
  • cystatin C (amyloid angiopathy and cerebral hemorrhage) (cst3)
  • hypothetical protein (cystatin 3)
  • cystatin C (Cst3)
  • ARMD11 protein
  • CYSC protein
  • fb51d07 protein
  • wu:fb24g06 protein
  • wu:fb51d07 protein
  • wu:fc55f03 protein
  • zgc:136227 protein

Protein level used designations for Cystatin C Proteins (CST3)

cystatin , egg-white cystatin , ovocystatin , cystatin C , cystatin-C , cystatin 3 , hypothetical protein , bA218C14.4 (cystatin C) , cystatin-3 , gamma-trace , neuroendocrine basic polypeptide , post-gamma-globulin , Cystatin C (cysteine proteinase inhibitor) , colostrum thiol proteinase inhibitor , cystatin C (amyloid angiopathy and cerebral hemorrhage)

GENE ID SPECIES
396497 Gallus gallus
733234 Xenopus laevis
791878 Danio rerio
100379852 Xenopus (Silurana) tropicalis
100462660 Felis catus
3238896 Cotesia congregata bracovirus
1471 Homo sapiens
13010 Mus musculus
733672 Sus scrofa
25307 Rattus norvegicus
100009450 Oryctolagus cuniculus
281102 Bos taurus
574313 Macaca mulatta
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