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anti-Cystatin E/M (CST6) Antibodies

The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Additionally we are shipping CST6 Proteins (15) and CST6 Kits (7) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
CST6 1474 Q15828
CST6 73720  
CST6 171096  
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Top anti-CST6 Antibodies at antibodies-online.com

Showing 10 out of 45 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated WB WB Suggested Anti-Cst6 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:312500Positive Control: Mouse Spleen WB Suggested Anti-Cst6  Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:.12500  Positive Control: Mouse Spleen 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated IHC, WB Immunohistochemical analysis of Cystatin E/M staining in human liver cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugad compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. Western blot analysis of Cystatin E/M expression in HEK293T (A), PC12 (B) whole cell lysates. 200 μL Log in to see 9 Days
$487.50
Details
Mouse Rabbit Un-conjugated IHC (p) Immunochemical staining of mouse CST6 in mouse skin with rabbit polyclonal antibody (1 µg/mL, formalin-fixed paraffin embedded sections). 100 μg Log in to see 16 Days
$218.90
Details
Human Mouse Un-conjugated ELISA   100 μg Log in to see 16 Days
$218.90
Details
Human Rabbit Un-conjugated ICC, IHC (fro), IHC (p), ELISA, WB 100 μg Log in to see 9 to 11 Days
$385.00
Details
Human Mouse Un-conjugated WB Western Blot analysis of CST6 expression in transfected 293T cell line by CST6 MaxPab polyclonal antibody.Lane 1: CST6 transfected lysate(16.39 KDa).Lane 2: Non-transfected lysate. 50 μL Log in to see 9 Days
$430.00
Details
Human Rabbit Un-conjugated ELISA, IHC   100 μL Log in to see 14 Days
$201.19
Details
Human Mouse Un-conjugated ELISA, WB Western Blot detection against Immunogen (35.9 KDa) . 50 μL Log in to see 9 Days
$298.57
Details
Human Rabbit Un-conjugated WB   100 μL Log in to see 14 Days
$369.79
Details
Human Mouse Un-conjugated ELISA, WB Western Blot analysis of CST6 expression in transfected 293T cell line by CST6 monoclonal antibody (M01), clone 2H8.Lane 1: CST6 transfected lysate (Predicted MW: 16.5 KDa).Lane 2: Non-transfected lysate. Western Blot detection against Immunogen (39.05 KDa) . 100 μg Log in to see 9 Days
$430.00
Details

CST6 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-CST6 Antibodies

  1. Human Polyclonal CST6 Primary Antibody for WB - ABIN2785432 : Veniaminova, Vagnozzi, Kopinke, Do, Murtaugh, Maillard, Dlugosz, Reiter, Wong: Keratin 79 identifies a novel population of migratory epithelial cells that initiates hair canal morphogenesis and regeneration. in Development (Cambridge, England) 2013 (PubMed)

More Antibodies against CST6 Interaction Partners

Human Cystatin E/M (CST6) interaction partners

  1. Low CST6 expression is associated with breast cancer.

  2. Developed a Methylation-Sensitive High Resolution Melting Analysis (MS-HRMA) assay for the investigation of CST6 promoter methylation in breast cancer patients.CST6 promoter was methylated in 39/80 of FFPEs.

  3. The CST6 promoter is highly methylated in circulating cell-free DNA of breast cancer patients, but not in healthy individuals.

  4. Data show a regulatory role of cystatin E/M in controlling both intra- and extracellular legumain (show LGMN Antibodies) activity.

  5. The ectopic expression of CST6 in cancer cells rescued mice from overt osteolytic metastasis and deaths in the animal study, while CST6 knockdown markedly enhanced cancer cell bone metastasis and shortened animal survival.

  6. An association between the quantity of CST6 methylation and the expression statuses of estrogen receptor (show ESR1 Antibodies), progesterone receptor (show PGR Antibodies), and HER4 (show ERBB4 Antibodies) in tumor tissues was found

  7. the level of cystatin E/M regulates legumain (show LGMN Antibodies) activity and hence the invasive potential of human melanoma cells

  8. CST6 is not a major gene contributing to type 1 and 2 harlequin ichthyosis

  9. Cystatin M suppresses the malignant phenotype of MDA-MB-435S cells.

  10. Complete loss of expression of cystatin M was observed in two of three stage IV breast cancer patients. Immunohistochemical studies confirmed that expression of cystatin M in IDCs was partially or completely lost.

Mouse (Murine) Cystatin E/M (CST6) interaction partners

  1. conclude that a tightly regulated balance between cathepsin L (show CTSL1 Antibodies) and cystatin M/E is essential for tissue integrity in epidermis, hair follicles, and corneal epithelium

  2. cystatin M/E has a role in skin barrier formation and a potential role as a tumor suppressor gene [review]

CST6 Antigen Profile

Protein Summary

The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins and the kininogens. The type 2 cystatin proteins are a class of cysteine proteinase inhibitors found in a variety of human fluids and secretions, where they appear to provide protective functions. This gene encodes a cystatin from the type 2 family, which is down-regulated in metastatic breast tumor cells as compared to primary tumor cells. Loss of expression is likely associated with the progression of a primary tumor to a metastatic phenotype.

Gene names and symbols associated with anti-Cystatin E/M (CST6) Antibodies

  • cystatin E/M (CST6) antibody
  • cystatin E/M (Cst6) antibody
  • 1110017E11Rik antibody
  • CST6 antibody
  • ichq antibody
  • N28197 antibody

Protein level used designations for anti-Cystatin E/M (CST6) Antibodies

cystatin E/M , cystatin M , cystatin-M , cystatin 6 , cystatin M/E , cystatin-6 , cystatin-E , cysteine proteinase inhibitor , harlequin ichthyosis , harlequin ichthysosis , cystatin N

GENE ID SPECIES
466668 Pan troglodytes
503685 Bos taurus
714999 Macaca mulatta
1474 Homo sapiens
483719 Canis lupus familiaris
73720 Mus musculus
171096 Rattus norvegicus
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