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The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Additionally we are shipping CST2 Antibodies (61) and CST2 Kits (5) and many more products for this protein.
Showing 10 out of 11 products:
Human CST2 Protein expressed in HEK-293 Cells - ABIN2180918
Dickinson, Thiesse, Hicks: Expression of type 2 cystatin genes CST1-CST5 in adult human tissues and the developing submandibular gland. in DNA and cell biology 2002
Show all 2 references for ABIN2180918
This data suggests an autoimmune mechanism behind chronic mucocutaneous candidiasis in autoimmune polyendocrine syndrome type I and provides rationale for evaluating cystatin (show CST3 Proteins) SA1 (show STAG1 Proteins) in antifungal therapy.
Identification of cystatin SA as a novel inhibitor of acid ceramidase (show ASAH1 Proteins).
cystatins SA1 (show STAG1 Proteins) and SA2 (show STAG2 Proteins) adhere to human fibroblasts and that the event results in tyrosine phosphorylation and upregulation of the release of IL-6 (show IL6 Proteins) mediated enhancement of NF-kappa B (show NFKB1 Proteins) activity.
Murine monoclonal antibodies were made which can distinguish between CST1 (show CST1 Proteins) and CST2.
The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins and the kininogens. The type 2 cystatin proteins are a class of cysteine proteinase inhibitors found in a variety of human fluids and secretions, where they appear to provide protective functions. The cystatin locus on chromosome 20 contains the majority of the type 2 cystatin genes and pseudogenes. This gene is located in the cystatin locus and encodes a secreted thiol protease inhibitor found at high levels in saliva, tears and seminal plasma.
, cystatin S5
, cysteine-proteinase inhibitor
, salivary cysteine (thiol) protease inhibitor