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Cysteine Rich Transmembrane BMP Regulator 1 (Chordin-Like) Proteins (CRIM1)

CRIM1 encodes a transmembrane protein containing six cysteine-rich repeat domains and an insulin-like growth factor-binding domain. Additionally we are shipping CRIM1 Antibodies (34) and CRIM1 Kits (6) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
CRIM1 50766 Q9JLL0
Rat CRIM1 CRIM1 298744  
CRIM1 51232 Q9NZV1
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Top CRIM1 Proteins at antibodies-online.com

Showing 5 out of 5 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 39 to 44 Days
$9,248.02
Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 69 to 74 Days
$12,906.52
Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 69 to 74 Days
$9,050.32
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 39 to 44 Days
$9,248.02
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details

CRIM1 Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine) ,
,
Human , ,
, ,

More Proteins for Cysteine Rich Transmembrane BMP Regulator 1 (Chordin-Like) (CRIM1) Interaction Partners

Mouse (Murine) Cysteine Rich Transmembrane BMP Regulator 1 (Chordin-Like) (CRIM1) interaction partners

  1. Crim1 regulates integrin signaling in murine lens development

  2. CRIM1 is the causative gene for Colobomatous macrophthalmia with microcornea syndrome and is important for eye development.

  3. Vascular endothelial cell-specific conditional compound heterozygotes for Crim1 and Vegfa (show VEGFA Proteins) exhibit a phenotype that is more severe than each single heterozygote and indistinguishable from that of the conditional homozygotes.

  4. Report the involvement of both endothelial cells and monocytes in the development of progressive renal fibrosis in Crim1 mutant mice.

  5. Crim1 mutations are associated with defects in papillary development and progression to chronic kidney disease later in life.

  6. Crim1 is required for placental development, and is necessary for the proper differentiation of sinusoidal-trophoblast giant cells and glycogen (show GYS1 Proteins) trophoblast cells.

  7. CRIM1 has a role in capillary formation and maintainance during angiogenesis

  8. CRIM1 modulates BMP activity by affecting its processing and delivery to the cell surface

  9. Crim1KST264/KST264 mice display a disruption of the Crim1 gene resulting in perinatal lethality with defects in multiple organ systems.

  10. Crim1 regulates the delivery of VEGF-A (show VEGFA Proteins) by the podocytes to the endothelial cells

Zebrafish Cysteine Rich Transmembrane BMP Regulator 1 (Chordin-Like) (CRIM1) interaction partners

  1. primary role of zebrafish crim1 is likely to be the regulation of somitic and vascular development

Human Cysteine Rich Transmembrane BMP Regulator 1 (Chordin-Like) (CRIM1) interaction partners

  1. These observations provide evidence for the first time that CRIM1 plays a role in cancer cells by enhancing the migration and adhesion and increasing the expression of N-CAD and E-CAD.

  2. CRIM1 is the causative gene for Colobomatous macrophthalmia with microcornea syndrome and is important for eye development.

  3. Knock down of CRIM1 had no effect on VEGF (show VEGFA Proteins)-induced proliferation or migration of umbilical vein endothelial cells (HUVECs), indicating that basal CRIM1 is not involved in the proliferation or migration of endothelial cells.

  4. Data suggest that CRIM1 plays role in cancer progression/metastasis, epithelial-mesenchymal transition, and neoplastic angiogenesis. [REVIEW]

  5. BMPs inhibitor CRIM1 is increased and correlates with higher levels of serum PIPIII showing an imbalance in favor of pro-fibrotic mechanisms in CHF.

  6. CRIM1 is an early response gene in the presence of both angiogenic stimulation (VEGF (show VEGFA Proteins)) and environmental (extracellular matrix) factors, and Erk (show EPHB2 Proteins) and FAK (show PTK2 Proteins) might be involved in the upregulation of CRIM1 mRNA expression in vascular endothelial cells.

  7. Study demonstrated that CRIM1 is expressed at high levels in resistant leukemia cells, indicating that CRIM1 may play a role in drug-resistance.

  8. CRIM1 has a role in capillary formation and maintenance during angiogenesis

  9. CRIM1 modulates BMP activity by affecting its processing and delivery to the cell surface

CRIM1 Protein Profile

Protein Summary

This gene encodes a transmembrane protein containing six cysteine-rich repeat domains and an insulin-like growth factor-binding domain. The encoded protein may play a role in tissue development though interactions with members of the transforming growth factor beta family, such as bone morphogenetic proteins.

Gene names and symbols associated with CRIM1

  • cysteine rich transmembrane BMP regulator 1 (chordin-like) (CRIM1)
  • cysteine rich transmembrane BMP regulator 1 (chordin like) (Crim1)
  • cysteine rich transmembrane BMP regulator 1 (chordin like) (crim1)
  • AU015004 protein
  • CRIM-1 protein
  • CRIM1 protein
  • S52 protein
  • wu:fc29f08 protein

Protein level used designations for CRIM1

cysteine rich transmembrane BMP regulator 1 (chordin-like) , cysteine-rich motor neuron 1 protein , cysteine-rich motor neuron 1 , cysteine-rich motor neuron 1 protein-like , CRIM-1 , cysteine rich transmembrane BMP regulator 1 , cysteine-rich repeat-containing protein S52 , cysteine-rich motorneuron 1

GENE ID SPECIES
475723 Canis lupus familiaris
506264 Bos taurus
711451 Macaca mulatta
746406 Pan troglodytes
100401932 Callithrix jacchus
100605761 Nomascus leucogenys
50766 Mus musculus
298744 Rattus norvegicus
404210 Danio rerio
51232 Homo sapiens
395067 Gallus gallus
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