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Cysteine-Rich Secretory Protein 1 Proteins (CRISP1)

Fertilization consists of a sequence of specific cell-cell interactions culminating in the fusion of the sperm and egg plasma membranes. Additionally we are shipping CRISP1 Antibodies (34) and CRISP1 Kits (4) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
CRISP1 78081  
CRISP1 167 P54107
CRISP1 64827 P12020
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Top CRISP1 Proteins at antibodies-online.com

Showing 7 out of 8 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Human Cells Mouse His tag 100 μg Log in to see 16 Days
$382.80
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
$2,570.33
Details
Yeast Macaca mulatta His tag   1 mg Log in to see 56 to 66 Days
$2,575.83
Details
Human Un-conjugated   100 μg Log in to see 4 to 5 Days
$4,044.15
Details

CRISP1 Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine) ,
,
Human ,
,
Rat (Rattus)

Top referenced CRISP1 Proteins

  1. Human CRISP1 Protein expressed in - ABIN1047968 : Wuttke, Müller, Nitsche, Paulsson, Hanisch, Maurer: Structural characterization of human recombinant and bone-derived bone sialoprotein. Functional implications for cell attachment and hydroxyapatite binding. in The Journal of biological chemistry 2001 (PubMed)
    Show all 2 references for ABIN1047968

More Proteins for Cysteine-Rich Secretory Protein 1 (CRISP1) Interaction Partners

Mouse (Murine) Cysteine-Rich Secretory Protein 1 (CRISP1) interaction partners

  1. patch clamping of sperm revealed that CRISP1 has the ability to regulate CatSper (show CATSPER1 Proteins), the principal sperm Ca(2 (show CA2 Proteins)+) channel involved in hyperactivation and essential for fertility

  2. These results suggest that CRISP1 may be an important structural component of mouse hair and that its strain-specific dysregulation may indicate a predisposition to hair shaft disease such as Alopecia areata

  3. This study showed that the loss of CRISP4 leads to a deficiency of the spermatozoa to undergo progesterone-induced acrosome reaction and to a decreased fertilizing ability of the sperm in the in vitro fertilization conditions.

  4. these data identify CRISP4 as an endogenous regulator of TRPM8 (show TRPM8 Proteins) with a role in normal sperm function.

  5. These results indicate that CRISP (show CRISP2 Proteins) proteins are players in the mammalian fertilization process.

  6. Crisp4 is expressed exclusively in epithelial cells of the epididymis in an androgen-dependent manner, and the expression of the gene starts at puberty along with the onset of sperm maturation. (CRISP4)

Human Cysteine-Rich Secretory Protein 1 (CRISP1) interaction partners

  1. Epididymal CRISP1 mediates sperm-zona pellucida binding through its interaction with ZP3 (show ZP3 Proteins).

  2. Seminal CRISP1 combined with neutral alpha glucosidase (show AGLU Proteins) activity can potentially distinguish between obstructive and nonobstructive azoospermia.

  3. CRISP1 was in the seminal plasma of normal and vasovasostomized men, but not in that of vasectomized men. The soluble concentration of CRISP1 was significantly higher in the seminal plasma of vasovasostomized men as compared with that from normal men.

CRISP1 Protein Profile

Protein Summary

Fertilization consists of a sequence of specific cell-cell interactions culminating in the fusion of the sperm and egg plasma membranes. Recognition, binding, and fusion occur through the interaction of complementary molecules that are localized to specific domains of the sperm and egg plasma membranes. In the sperm, the postacrosomal region or equatorial segment is involved in sperm-egg plasma membrane fusion. The protein encoded by this gene is a member of the cysteine-rich secretory protein (CRISP) family. It is expressed in the epididymis, is secreted into the epididymal lumen, and binds to the postacrosomal region of the sperm head, where it plays a role in sperm-egg fusion. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with CRISP1

  • cysteine-rich secretory protein 4 (Crisp4)
  • cysteine-rich secretory protein 1 (CRISP1)
  • cysteine-rich secretory protein 1 (Crisp1)
  • 9230112K08Rik protein
  • AEG protein
  • Aeg1 protein
  • AEGL1 protein
  • ARP protein
  • AW324342 protein
  • Crisp-1 protein
  • HSCRISP1D protein
  • HSCRISP1G protein
  • HUMARP protein

Protein level used designations for CRISP1

cysteine-rich secretory protein 1 , acidic epididymal glycoprotein-like 1 , cystein rich secretory protein 1 , cysteine-rich secretory protein-1 , AEG-like protein , AEG-related protein , acidic epididymal glycoprotein homolog , cysteine-rich secretory protein-1 delta , SCP 1 , acidic epididymal glycoprotein 1 , sperm-coating glycoprotein 1 , 32 kDa epididymal protein , SCP , acidic epididymal glycoprotein D/E , epididymal glycoprotein , protein D , protein E , protein IV , sialoprotein , sperm-coating glycoprotein , mAEG , CRISP-1 , androgen-dependent acidic epididymal glycoprotein

GENE ID SPECIES
78081 Mus musculus
610137 Canis lupus familiaris
740481 Pan troglodytes
100033953 Equus caballus
167 Homo sapiens
396812 Sus scrofa
616774 Bos taurus
11571 Mus musculus
64827 Rattus norvegicus
574111 Macaca mulatta
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