Cysteine-Rich Secretory Protein 1 Proteins (CRISP1)

Fertilization consists of a sequence of specific cell-cell interactions culminating in the fusion of the sperm and egg plasma membranes. Additionally we are shipping CRISP1 Antibodies (34) and CRISP1 Kits (4) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
CRISP1 167 P54107
CRISP1 78081  
CRISP1 64827 P12020
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Top CRISP1 Proteins at antibodies-online.com

Showing 9 out of 10 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 50 Days
$5,442.50
Details
Insect Cells Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 50 Days
$5,442.50
Details
Human Cells Mouse Fc Tag 50 μg Log in to see 20 to 21 Days
$250.80
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Human Un-conjugated   100 μg Log in to see 5 to 6 Days
$4,044.15
Details
Wheat germ Human GST tag 10 μg Log in to see 11 to 12 Days
$405.71
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Yeast Rat His tag   1 mg Log in to see 60 to 71 Days
$2,570.33
Details
Yeast Macaca mulatta His tag   1 mg Log in to see 60 to 71 Days
$2,575.83
Details
Escherichia coli (E. coli) Rat T7 tag,His tag   100 μg Log in to see 15 to 18 Days
$672.00
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Escherichia coli (E. coli) Mouse T7 tag,His tag   100 μg Log in to see 15 to 18 Days
$688.00
Details

CRISP1 Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,
,
Mouse (Murine) , ,
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Rat (Rattus) ,
,

Top referenced CRISP1 Proteins

  1. Human CRISP1 Protein expressed in - ABIN1047968 : Wuttke, Müller, Nitsche, Paulsson, Hanisch, Maurer: Structural characterization of human recombinant and bone-derived bone sialoprotein. Functional implications for cell attachment and hydroxyapatite binding. in The Journal of biological chemistry 2001 (PubMed)
    Show all 2 Pubmed References

More Proteins for Cysteine-Rich Secretory Protein 1 (CRISP1) Interaction Partners

Mouse (Murine) Cysteine-Rich Secretory Protein 1 (CRISP1) interaction partners

  1. The obesity-induced decline in sperm motility and fertilization capacity results in part from the disruption of epididymal CRISP4 expression and secretion.

  2. Up regulation of AEG protein plays a role in the pathogenesis of NAFLD.

  3. patch clamping of sperm revealed that CRISP1 has the ability to regulate CatSper (show CATSPER1 Proteins), the principal sperm Ca(2 (show CA2 Proteins)+) channel involved in hyperactivation and essential for fertility

  4. These results suggest that CRISP1 may be an important structural component of mouse hair and that its strain-specific dysregulation may indicate a predisposition to hair shaft disease such as Alopecia areata

  5. This study showed that the loss of CRISP4 leads to a deficiency of the spermatozoa to undergo progesterone-induced acrosome reaction and to a decreased fertilizing ability of the sperm in the in vitro fertilization conditions.

  6. these data identify CRISP4 as an endogenous regulator of TRPM8 (show TRPM8 Proteins) with a role in normal sperm function.

  7. Crisp4 is expressed exclusively in epithelial cells of the epididymis in an androgen-dependent manner, and the expression of the gene starts at puberty along with the onset of sperm maturation. (CRISP4)

  8. These results indicate that CRISP (show CRISP2 Proteins) proteins are players in the mammalian fertilization process.

Human Cysteine-Rich Secretory Protein 1 (CRISP1) interaction partners

  1. Epididymal CRISP1 mediates sperm-zona pellucida binding through its interaction with ZP3 (show ZP3 Proteins).

  2. Seminal CRISP1 combined with neutral alpha glucosidase (show AGLU Proteins) activity can potentially distinguish between obstructive and nonobstructive azoospermia.

  3. CRISP1 was in the seminal plasma of normal and vasovasostomized men, but not in that of vasectomized men. The soluble concentration of CRISP1 was significantly higher in the seminal plasma of vasovasostomized men as compared with that from normal men.

CRISP1 Protein Profile

Protein Summary

Fertilization consists of a sequence of specific cell-cell interactions culminating in the fusion of the sperm and egg plasma membranes. Recognition, binding, and fusion occur through the interaction of complementary molecules that are localized to specific domains of the sperm and egg plasma membranes. In the sperm, the postacrosomal region or equatorial segment is involved in sperm-egg plasma membrane fusion. The protein encoded by this gene is a member of the cysteine-rich secretory protein (CRISP) family. It is expressed in the epididymis, is secreted into the epididymal lumen, and binds to the postacrosomal region of the sperm head, where it plays a role in sperm-egg fusion. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with CRISP1

  • cysteine rich secretory protein 1 (CRISP1)
  • cysteine-rich secretory protein 4 (Crisp4)
  • cysteine-rich secretory protein 1 (Crisp1)
  • cysteine-rich secretory protein 3 (Crisp3)
  • 9230112K08Rik protein
  • Aeg protein
  • Aeg1 protein
  • AEGL1 protein
  • ARP protein
  • AW324342 protein
  • Crisp-1 protein
  • HSCRISP1D protein
  • HSCRISP1G protein
  • HUMARP protein

Protein level used designations for CRISP1

AEG-like protein , AEG-related protein , acidic epididymal glycoprotein homolog , acidic epididymal glycoprotein-like 1 , cysteine-rich secretory protein-1 delta , SCP 1 , acidic epididymal glycoprotein 1 , sperm-coating glycoprotein 1 , cysteine-rich secretory protein 1 , mAEG , CRISP-1 , androgen-dependent acidic epididymal glycoprotein , cystein rich secretory protein 1 , cysteine-rich secretory protein-1 , 32 kDa epididymal protein , SCP , acidic epididymal glycoprotein D/E , epididymal glycoprotein , protein D , protein E , protein IV , sialoprotein , sperm-coating glycoprotein

GENE ID SPECIES
167 Homo sapiens
78081 Mus musculus
11571 Mus musculus
574111 Macaca mulatta
740481 Pan troglodytes
100033953 Equus caballus
396812 Sus scrofa
616774 Bos taurus
64827 Rattus norvegicus
100860898 Capra hircus
100855553 Canis lupus familiaris
100359052 Oryctolagus cuniculus
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