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putative cysteinyl leukotriene receptor [RGD, Feb 2006].. Additionally we are shipping CasLTR2 Antibodies (53) and CasLTR2 Proteins (3) and many more products for this protein.
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CysLT2 receptors were expressed in lung specimens isolated from asthma subjects. Activation of CysLT2 receptors may contribute to antigen-induced bronchoconstriction in certain asthma population.
CysLTR-1 (show CYSLTR1 ELISA Kits) and CysLTR-2 are highly expressed in the adenoid tissues from children with AH, suggesting that leukotrienes are involved in the pathogenesis of AH.
Suggest that endothelial and nonendothelial CysLT2R niches have separate roles in mediating inflammatory responses in ischemic/perfusion injury.
ATRA treatment induces CysLT(2)R mRNA and protein expression in colon cancer cell lines
CysLT2 receptor plays a primary role in the vascular responses in the upper respiratory tract.
There is a protective role against tumor progression for CysLT(2)R and that it highlights new possibilities to regulate the CysLT(2)R.
The synthesis of cys (show DNAJC5 ELISA Kits)-LTs from LTA (show LTA ELISA Kits)(4) by endothelial cells is directly associated with the activation of the CysLT(2) receptor in a typical autocrine fashion.
Cysteinyl leukotriene receptor 2 gene polymorphism -1220 A/C is not associated with atopic dermatitis or psoriasis vulgaris in Japanese patients.
upon ligand activation, CysLT(1 (show CYSLTR1 ELISA Kits))R is tyrosine-phosphorylated and released from heterodimers with CysLT(2)R and, subsequently, internalizes from the plasma membrane to the nuclear membrane in a clathrin-, arrestin-3 (show ARRB2 ELISA Kits)-, and Rab-5 (show RAB5A ELISA Kits)-dependent manner
results indicate that the M201V polymorphism drastically affects CysLT(2) responses to LTD(4) and less to LTC(4)
The CysLT(1 (show CYSLTR1 ELISA Kits)) and CysLT(2) receptors were primarily localized in neurons, microglia and neutrophils
LTC4 activates mouse platelets exclusively through CysLT2R. LTC4/CysLT2R signaling required an autocrine ADP-mediated response through P2Y12 (show P2RY12 ELISA Kits) receptors.
CysLT1R (show CYSLTR1 ELISA Kits), CysLT2R and GPR17 (show GPR17 ELISA Kits) might be involved in the MPTP (show PTPN2 ELISA Kits)-induced Parkinson disease damage in mice.
CysLT2R negatively regulates the development of cys (show DNAJC5 ELISA Kits)-LT-dependent T helper cell (Th)2 pulmonary inflammation by inhibiting both CysLT1R (show CYSLTR1 ELISA Kits) signaling and house dust mite-induced LTC4S (show LTC4S ELISA Kits)-dependent cell surface expression of CysLT1R (show CYSLTR1 ELISA Kits) on dendritic cells.
These findings establish a role for eosinophil-derived cysteinyl leukotriene and the CysLT(2)R in the hyperkeratosis and fibrosis of allergic skin inflammation.
Results implicate the CysLT(2)R in the progression of ischemic retinopathy.
These results suggest that a lack of neuronal expression of CysLTR (show CYSLTR1 ELISA Kits) in the murine colonic myenteric plexus attenuates colitis disease progression.
findings show that CysLT1 receptor (show CYSLTR1 ELISA Kits) attenuates while CysLT2 receptor facilitates oxygen glucose deprivation -induced PC12 cell death
CysLT2 receptors interact with CysLT1 (show CYSLTR1 ELISA Kits) receptors and down-modulate cysteinyl leukotriene dependent mitogenic responses of mast cells.
In luteal-phase endometrium, expression of 5-LO (5-lipoxygenase (show ALOX5 ELISA Kits)) and LTB4R (leukotriene B4 receptor) is highest on Days 2-4; expression of LTCS (leukotriene-C4 synthase (show LTC4S ELISA Kits)) and CysLTR2 (cysteinyl leukotriene receptor 2) is highest on Days 16-18. In luteal-phase endometrium, LTB4 (show PTGR1 ELISA Kits) level is highest on Days 2-4; LTC4 level is highest on Days 16-18. Studies were conducted in Poland on Holstein Polish Black and White dairy cows.
putative cysteinyl leukotriene receptor
cysteinyl leukotriene receptor 2
, G protein-coupled receptor
, G-protein coupled receptor GPCR21
, G-protein coupled receptor HG57
, cysteinyl leukotriene CysLT2 receptor