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CARS encodes a class 1 aminoacyl-tRNA synthetase, cysteinyl-tRNA synthetase. Additionally we are shipping Cysteinyl-tRNA Synthetase Antibodies (41) and Cysteinyl-tRNA Synthetase Proteins (6) and many more products for this protein.
Loss of CARS, the cysteinyl-tRNA synthetase, suppresses ferroptosis induced by erastin, which inhibits the cystine-glutamate (show GRIN1 ELISA Kits) antiporter known as system xc(-).
CARS is a novel fusion partner of anaplastic lymphoma kinase in anaplastic large-cell lymphoma and inflammatory myofibroblastic tumor cases.
Specificity of anticodon recognition by human CysRS is higher than that of its bacterial counterparts.
This gene encodes a class 1 aminoacyl-tRNA synthetase, cysteinyl-tRNA synthetase. Each of the twenty aminoacyl-tRNA synthetases catalyzes the aminoacylation of a specific tRNA or tRNA isoaccepting family with the cognate amino acid. This gene is one of several located near the imprinted gene domain on chromosome 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocortical carcinoma, and lung, ovarian and breast cancers. Alternative splicing of this gene results in multiple transcript variants.
cysteinyl-tRNA synthetase, cytoplasmic
, cysteinyl-tRNA synthetase
, cysteine--tRNA ligase, cytoplasmic
, cysteine-tRNA ligase
, cysteine tRNA ligase 1, cytoplasmic
, cysteine translase