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anti-Cystic Fibrosis Transmembrane Conductance Regulator (ATP-Binding Cassette Sub-Family C, Member 7) (CFTR) Antibodies

CFTR encodes a member of the ATP-binding cassette (ABC) transporter superfamily. Additionally we are shipping CFTR Kits (38) and CFTR Proteins (7) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
CFTR 12638 P26361
CFTR 24255 P34158
CFTR 1080 P13569
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Top anti-CFTR Antibodies at antibodies-online.com

Showing 10 out of 87 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Mouse Un-conjugated IHC (p) Formalin fixed paraffin embedded human pancreas stained with CFTR antibody ABIN115197 1 mL Log in to see 6 to 8 Days
$786.50
Details
Human Rabbit Un-conjugated IF, IHC (p) 0.1 mg Log in to see 6 to 8 Days
$390.50
Details
Human Mouse Un-conjugated IF, IP, WB   0.1 mg Log in to see 10 to 12 Days
$600.60
Details
Human Mouse Un-conjugated IP, IHC, WB   200 μg Log in to see 3 to 4 Days
$777.50
Details
Human Goat Un-conjugated IHC (p) AP23980PU-N ABCC7/CFTR antibody staining of Formalin-Fixed, Paraffin-Embedded Human Kidney. AP23980PU-N ABCC7/CFTR antibody staining of Formalin-Fixed, Paraffin-Embedded Human Prostate. 50 μg Log in to see 6 to 8 Days
$500.50
Details
Human Rabbit Un-conjugated IHC (p), WB Anti-CFTR antibody, Western blotting WB: Rat Pancreas Tissue Lysate Anti-CFTR antibody, IHC(P) IHC(P): Human Pancreatic Cancer Tissue 100 μg Log in to see 4 to 6 Days
$200.00
Details
Human Rabbit Un-conjugated IHC, ELISA, WB Western blot analysis of extracts from NIH-3T3 cells, using CFTR (Ab-737) Antibody. The lane on the right is treated with the synthesized peptide. Immunohistochemistry analysis of paraffin-embedded human colon carcinoma tissue, using CFTR (Ab-737) Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Mouse Un-conjugated WB 0.1 mg Log in to see 6 to 8 Days
$346.50
Details
Human Mouse Un-conjugated IF, IHC (p), IP Human Lung: Formalin-Fixed, Paraffin-Embedded (FFPE) 250 μL Log in to see 8 to 10 Days
$595.83
Details
Human Rabbit Un-conjugated IHC, WB Immunohistochemical analysis of CFTR staining in human brain formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugad compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. w Western blot analysis of CFTR expression in SHSY5Y (A), NIH3T3 (B) whole cell lysates. 200 μL Log in to see 9 Days
$487.50
Details

CFTR Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-CFTR Antibodies

  1. Human Monoclonal CFTR Primary Antibody for IHC (p) - ABIN115197 : Sealock, Butler, Kramarcy, Gao, Murnane, Douville, Froehner: Localization of dystrophin relative to acetylcholine receptor domains in electric tissue and adult and cultured skeletal muscle. in The Journal of cell biology 1991 (PubMed)

  2. Human Monoclonal CFTR Primary Antibody for IF, IP - ABIN180604 : Kartner, Augustinas, Jensen, Naismith, Riordan: Mislocalization of delta F508 CFTR in cystic fibrosis sweat gland. in Nature genetics 1993 (PubMed)

More Antibodies against CFTR Interaction Partners

Xenopus laevis Cystic Fibrosis Transmembrane Conductance Regulator (ATP-Binding Cassette Sub-Family C, Member 7) (CFTR) interaction partners

  1. NDPK-A (show NME1 Antibodies) exists in a functional cellular complex with AMPK (show PRKAA2 Antibodies) and CFTR in airway epithelia, and NDPK-A (show NME1 Antibodies) catalytic function is required for the AMPK (show PRKAA2 Antibodies)-dependent regulation of CFTR

  2. Study conclude that when both CFTR and NPT2a (show SLC34A1 Antibodies) are expressed in X. laevis oocytes, CFTR confers to NPT2a (show SLC34A1 Antibodies) a cAMPi-dependent trafficking to the membrane.

  3. wild-type CFTR channel gating cycle is essentially irreversible and tightly coupled to the ATPase (show DNAH8 Antibodies) cycle, and that this coupling is completely destroyed by the NBD2 Walker B mutation D1370N but only partially disrupted by the NBD1 Walker A mutation K464A.

  4. The cystic fibrosis transmembrane conductance regulator (CFTR) is a protein that belongs to the superfamily of ATP binding cassette (ABC (show ABCB6 Antibodies)) transporters.

  5. These data suggest that the Xenopus P2Y1 receptor (show P2RY1 Antibodies) can increase both cyclic AMP (show TMPRSS5 Antibodies)/protein kinase A and calcium/protein kinase C (show PKC Antibodies) levels and that the PKC (show PKC Antibodies) pathway is involved in CFTR activation via potentiation of the PKA pathway.

Mouse (Murine) Cystic Fibrosis Transmembrane Conductance Regulator (ATP-Binding Cassette Sub-Family C, Member 7) (CFTR) interaction partners

  1. CFTR expressed by alveolar or peritoneal macrophages regulates acute proinflammatory responses.

  2. CFTR silencing in pancreatic beta-cells significantly reduced insulin (show INS Antibodies) output in response to glucose, and made the cells more sensitive to oxidative stress.

  3. Cftr KO crypt epithelium maintains an alkaline pHi as a consequence of losing both Cl(-) and HCO3 (-) efflux, which impairs pHi regulation by Ae2 (show SLC4A2 Antibodies).

  4. Data suggest that the deltaF508 Cftr mutation (the most frequent CFTR mutation in cystic fibrosis (show S100A8 Antibodies) in humans) is associated with worsening insulin (show INS Antibodies) resistance and down-regulation of insulin (show INS Antibodies) secretion from pancreatic beta cells as mutant mice age.

  5. Second-hand cigarette impairs bacterial phagocytosis by modulating CFTR dependent lipid-rafts.

  6. CFTR Cl- channel is a molecular target of natural compounds EGCG and ECG.

  7. lipoxin A4 and PAF (show KIAA0101 Antibodies) are involved in E. coli or LPS (show TLR4 Antibodies)-induced lung inflammation in CFTR-deficient mice.

  8. Osteoblast dysfunctions in DeltaF508-CFTR mice result from altered NF-kappaB (show NFKB1 Antibodies) and Wnt (show WNT2 Antibodies)/beta-catenin (show CTNNB1 Antibodies) signaling.

  9. CFTR and BECN1 (show BECN1 Antibodies) function can be restored with cysteamine and EGCG in a model of the F508del-CFTR mutation

  10. The data of this study strengthen the notion that microvillar cells in the OE play a key role in maintaining tissue homeostasis and identify several mechanisms underlying this regulation through the multiple functions of CFTR.

Human Cystic Fibrosis Transmembrane Conductance Regulator (ATP-Binding Cassette Sub-Family C, Member 7) (CFTR) interaction partners

  1. G551D-bearing Cystic fibrosis (show S100A8 Antibodies) patients had significantly higher expression of active CD11b (show ITGAM Antibodies) on polymorphonuclear neutrophils and of CD63 (show CD63 Antibodies) on monocytes.

  2. We found that cyclophosphamide significantly enhanced long-term expression of the transgenic human CFTR and the reporter gene LacZ (show GLB1 Antibodies) by reducing host immune responses.

  3. The study helps expand our knowledge of rare CFTR mutations in a minority population and may have important clinical implications for personalized therapeutic intervention.

  4. Studies indicate that the main strategies used in the molecular diagnosis of cystic fibrosis (show S100A8 Antibodies) are detecting and sequencing of the entire coding region of the cystic fibrosis transmembrane conductance regulator (CFTR) gene.

  5. adenovirusmediated CFTR overexpression enhanced cell invasion and motility of serous ovarian cancer cells in vitro.

  6. Letter/Case Report: high penetrance of the PRSS1 (show PRSS1 Antibodies) A16V mutation caused by SPINK1 (show SPINK1 Antibodies) N34S and CFTR TG11-5T co-mutations associated with pancreatitis.

  7. The most common cystic fibrosis (show S100A8 Antibodies) causing mutation is the deletion of F508 from the first Nucleotide Binding Domain (F508del-NBD1). The study releals the mechanism of action of deleterious, rescuing, and stabilizing perturbations to NBD1 from CFTR.

  8. KCa3.1 (show KCNN4 Antibodies) and CFTR colocalize at the plasma membrane.

  9. Studies suggest that subtle changes in cystic fibrosis transmembrane conductance regulator (CFTR) structure can affect strongly channel function and the action of cystic fibrosis (show S100A8 Antibodies) (CF) mutations.

  10. Analysis of long-range interactions in primary human cells identifies novel cooperative CFTR regulatory elements.

Pig (Porcine) Cystic Fibrosis Transmembrane Conductance Regulator (ATP-Binding Cassette Sub-Family C, Member 7) (CFTR) interaction partners

  1. Results suggest that acetylcholine does not regulate the activity of the CFTR in tracheal epithelia of pigs which opposes observation from studies using mice airway epithelium.

  2. Expression of CFTR-F508del interferes with smooth muscle cell calcium handling and decreases aortic responsiveness.

  3. Pseudomonas aeruginosa and other bacteria into the lumen of intact isolated swine tracheas triggers CFTR-dependent airway surface liquid secretion by the submucosal glands.

  4. TGF-beta1 (show TGFB1 Antibodies), via TGF-beta1 (show TGFB1 Antibodies) receptor I and p38 MAPK (show MAPK14 Antibodies) signaling, reduces CFTR expression to impair CFTR-mediated anion secretion, which would likely compound the effects associated with mild CFTR mutations and ultimately would compromise male fertility.

  5. The esophageal submucosal glands (SMG (show SNRPG Antibodies)) secrete HCO(3)(-) and mucus into the esophageal lumen, where they contribute to acid clearance and epithelial protection. We investigated the presence of CFTR, its involvement in the secretion process, and the effect of cAMP on HCO3 secretion in this tissue. This is the first report on the presence of CFTR channels in the esophagus.

  6. data suggest that loss of CFTR directly alters Schwann cell function and that some nervous system defects in people with cystic fibrosis (show S100A8 Antibodies) are likely primary

  7. The data suggest, that during bacterial infections and resulting release of proinflammatory cytokines, the glands are stimulated to secrete fluid, and this response is mediated by cAMP-activated CFTR.

  8. CFTR is required for maximal liquid absorption by lung alveoli under cAMP stimulation

  9. These findings reveal differences between nasal and tracheal glands, show defective fluid secretion in nasal glands of cystic fibrosis (show S100A8 Antibodies) pigs, reveal some spared function in the DeltaF508 vs. null piglets.

  10. causal link between CFTR mutations and partial or total vas (show AVP Antibodies) deferens and/or epididymis atresia at birth

Cow (Bovine) Cystic Fibrosis Transmembrane Conductance Regulator (ATP-Binding Cassette Sub-Family C, Member 7) (CFTR) interaction partners

  1. conserved CFTR sequences between species are examined for potential regulatory elements. Regions of introns 2, 3, 10, 17a, 18, and 21 and 3' flanking sequence corresponding to human CFTR DNase I (show DNASE1 Antibodies) hypersensitive sites showed high homology in cow and pig.

Guinea Pig Cystic Fibrosis Transmembrane Conductance Regulator (ATP-Binding Cassette Sub-Family C, Member 7) (CFTR) interaction partners

  1. Results demonstrate functional coupling between Cftr and Slc26a6 (show SLC26A6 Antibodies)-like Cl(-)/HCO(3)(-) exchange activity in apical membrane of guinea pig pancreatic interlobular duct.

CFTR Antigen Profile

Protein Summary

This gene encodes a member of the ATP-binding cassette (ABC) transporter superfamily. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily that is involved in multi-drug resistance. The encoded protein functions as a chloride channel and controls the regulation of other transport pathways. Mutations in this gene are associated with the autosomal recessive disorders cystic fibrosis and congenital bilateral aplasia of the vas deferens. Alternatively spliced transcript variants have been described, many of which result from mutations in this gene.

Gene names and symbols associated with CFTR

  • cystic fibrosis transmembrane conductance regulator (cftr-A) antibody
  • cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) (CFTR) antibody
  • cystic fibrosis transmembrane conductance regulator (Cftr) antibody
  • cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) (Cftr) antibody
  • cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) (cftr) antibody
  • cystic fibrosis transmembrane conductance regulator homolog (Cftr) antibody
  • abc35 antibody
  • abcc7 antibody
  • AW495489 antibody
  • CF antibody
  • CFTR antibody
  • cftr/mrp antibody
  • dJ760C5.1 antibody
  • mrp7 antibody
  • RGD1561193 antibody
  • tnr-cftr antibody
  • xcftr antibody

Protein level used designations for CFTR

cystic fibrosis transmembrane conductance regulator , cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) , cystic fibrosis transmembrane conductance regulator, ATP-binding cassette (sub-family C, member 7) , ATP-binding cassette sub-family C member 7 , ATP-binding cassette transporter sub-family C member 7 , ATP-binding cassette, subfamily c, member 7 , cAMP-dependent chloride channel , channel conductance-controlling ATPase , cystic fibrosis transmembrane conductance regulator homolog , cystic fibrosis transmembrane conductance regulator homolog; ATP-binding cassette, subfamily c, member 7 , CFTR chloride channel , chloride channel , CFTR cAMP-dependent chloride channel protein , Channel conductance-controlling ATPase

GENE ID SPECIES
373725 Xenopus laevis
780954 Monodelphis domestica
100137161 Nomascus leucogenys
12638 Mus musculus
24255 Rattus norvegicus
1080 Homo sapiens
100049619 Gallus gallus
492302 Canis lupus familiaris
403154 Sus scrofa
281067 Bos taurus
100009471 Oryctolagus cuniculus
100719898 Cavia porcellus
100071259 Equus caballus
443347 Ovis aries
100381094 Xenopus laevis
100137035 Pongo abelii
463674 Pan troglodytes
100126675 Papio anubis
100135647 Cavia porcellus
Selected quality suppliers for anti-CFTR (CFTR) Antibodies
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