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Cystic Fibrosis Transmembrane Conductance Regulator (ATP-Binding Cassette Sub-Family C, Member 7) (CFTR) ELISA Kits

CFTR encodes a member of the ATP-binding cassette (ABC) transporter superfamily. Additionally we are shipping Cystic Fibrosis Transmembrane Conductance Regulator (ATP-Binding Cassette Sub-Family C, Member 7) Antibodies (82) and Cystic Fibrosis Transmembrane Conductance Regulator (ATP-Binding Cassette Sub-Family C, Member 7) Proteins (7) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
CFTR 12638 P26361
CFTR 24255 P34158
CFTR 1080 P13569
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Top Cystic Fibrosis Transmembrane Conductance Regulator (ATP-Binding Cassette Sub-Family C, Member 7) ELISA Kits at antibodies-online.com

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Catalog No. Reactivity Sensitivity Range Images Quantity Supplier Delivery Price Details
Human 0.053 ng/mL 0.15-10 ng/mL 96 Tests Log in to see 9 to 11 Days
$736.84
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Dog 4.69 pg/ml 18.75-1200 pg/mL   96 Tests Log in to see 11 to 13 Days
$1,026.67
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Pig
  96 Tests Log in to see 8 to 9 Days
$770.00
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Chicken
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Rabbit
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$770.00
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Guinea Pig
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$770.00
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Monkey
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$770.00
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Rat
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$785.71
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Mouse
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Dog
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More ELISA Kits for Cystic Fibrosis Transmembrane Conductance Regulator (ATP-Binding Cassette Sub-Family C, Member 7) Interaction Partners

Xenopus laevis Cystic Fibrosis Transmembrane Conductance Regulator (ATP-Binding Cassette Sub-Family C, Member 7) (CFTR) interaction partners

  1. NDPK-A (show NME1 ELISA Kits) exists in a functional cellular complex with AMPK (show PRKAA2 ELISA Kits) and CFTR in airway epithelia, and NDPK-A (show NME1 ELISA Kits) catalytic function is required for the AMPK (show PRKAA2 ELISA Kits)-dependent regulation of CFTR

  2. Study conclude that when both CFTR and NPT2a (show SLC34A1 ELISA Kits) are expressed in X. laevis oocytes, CFTR confers to NPT2a (show SLC34A1 ELISA Kits) a cAMPi-dependent trafficking to the membrane.

  3. wild-type CFTR channel gating cycle is essentially irreversible and tightly coupled to the ATPase (show DNAH8 ELISA Kits) cycle, and that this coupling is completely destroyed by the NBD2 Walker B mutation D1370N but only partially disrupted by the NBD1 Walker A mutation K464A.

  4. The cystic fibrosis transmembrane conductance regulator (CFTR) is a protein that belongs to the superfamily of ATP binding cassette (ABC (show ABCB6 ELISA Kits)) transporters.

  5. These data suggest that the Xenopus P2Y1 receptor (show P2RY1 ELISA Kits) can increase both cyclic AMP (show TMPRSS5 ELISA Kits)/protein kinase A and calcium/protein kinase C (show PKC ELISA Kits) levels and that the PKC (show PKC ELISA Kits) pathway is involved in CFTR activation via potentiation of the PKA pathway.

Mouse (Murine) Cystic Fibrosis Transmembrane Conductance Regulator (ATP-Binding Cassette Sub-Family C, Member 7) (CFTR) interaction partners

  1. CFTR silencing in pancreatic beta-cells significantly reduced insulin (show INS ELISA Kits) output in response to glucose, and made the cells more sensitive to oxidative stress.

  2. Cftr KO crypt epithelium maintains an alkaline pHi as a consequence of losing both Cl(-) and HCO3 (-) efflux, which impairs pHi regulation by Ae2 (show SLC4A2 ELISA Kits).

  3. Data suggest that the deltaF508 Cftr mutation (the most frequent CFTR mutation in cystic fibrosis (show S100A8 ELISA Kits) in humans) is associated with worsening insulin (show INS ELISA Kits) resistance and down-regulation of insulin (show INS ELISA Kits) secretion from pancreatic beta cells as mutant mice age.

  4. Second-hand cigarette impairs bacterial phagocytosis by modulating CFTR dependent lipid-rafts.

  5. CFTR Cl- channel is a molecular target of natural compounds EGCG and ECG.

  6. lipoxin A4 and PAF (show KIAA0101 ELISA Kits) are involved in E. coli or LPS (show TLR4 ELISA Kits)-induced lung inflammation in CFTR-deficient mice.

  7. Osteoblast dysfunctions in DeltaF508-CFTR mice result from altered NF-kappaB (show NFKB1 ELISA Kits) and Wnt (show WNT2 ELISA Kits)/beta-catenin (show CTNNB1 ELISA Kits) signaling.

  8. CFTR and BECN1 (show BECN1 ELISA Kits) function can be restored with cysteamine and EGCG in a model of the F508del-CFTR mutation

  9. The data of this study strengthen the notion that microvillar cells in the OE play a key role in maintaining tissue homeostasis and identify several mechanisms underlying this regulation through the multiple functions of CFTR.

  10. we have shown that DeltaF508cftr-/- mice with defective CFTR exhibit delayed wound healing as compared to wild type mice, indicating that normal function of CFTR is critical for wound repair

Human Cystic Fibrosis Transmembrane Conductance Regulator (ATP-Binding Cassette Sub-Family C, Member 7) (CFTR) interaction partners

  1. Data show that hypotonicity activated cystic fibrosis transmembrane conductance regulator (CFTR) channels in airway Calu (show CALU ELISA Kits)-3 epithelial cells.

  2. Data suggest that post-translational modifications, both phosphorylation and glycosylation, are important in regulation of CFTR activity; two N-linked glycosylation sites, located at positions 594 and 600, are of particular importance. [REVIEW]

  3. CFTR gating and ATP hydrolysis require a properly configured transmembrane domain interface.

  4. Hsp27-Ubc9 pathway recognizes the conformation of mutant CFTR which leads to its SUMO-2 conjugation and degradation by the ubiquitin-proteasome system.

  5. Case Report: Isolated liver disease in a patient with a CFTR genotype F508del/12TG-5T and 470MV.

  6. Role of Interaction and Nucleoside Diphosphate Kinase B in Regulation of the Cystic Fibrosis Transmembrane Conductance Regulator Function by cAMP-Dependent Protein Kinase A

  7. Each normally required for CFTR activity.

  8. we determined the total information content of the approach for 19 common mutations registration in the CFTR gene, 84.6%, and the allelic frequencies of the examined mutations

  9. we provide novel elements in the mechanism of hsa (show CD24 ELISA Kits)-miR (show MLXIP ELISA Kits)-99b and hsa (show CD24 ELISA Kits)-miR (show MLXIP ELISA Kits)-125a biogenesis, and for the role of CFTR and DeltaF508-CFTR on the expression of this miRNA cluster. These findings augment existing data implicating miRNAs as putative CF modifiers.

  10. Findings suggest that defects in CFTR may increase susceptibility of mice to lung infections with the highly mucoid serotype 3 streptococcus pneumoniae despite similar lung histopathology and levels of TNF-alpha (show TNF ELISA Kits) and CXCL1/KC (show CXCL1 ELISA Kits) produced early in infection.

Pig (Porcine) Cystic Fibrosis Transmembrane Conductance Regulator (ATP-Binding Cassette Sub-Family C, Member 7) (CFTR) interaction partners

  1. Expression of CFTR-F508del interferes with smooth muscle cell calcium handling and decreases aortic responsiveness.

  2. Pseudomonas aeruginosa and other bacteria into the lumen of intact isolated swine tracheas triggers CFTR-dependent airway surface liquid secretion by the submucosal glands.

  3. TGF-beta1 (show TGFB1 ELISA Kits), via TGF-beta1 (show TGFB1 ELISA Kits) receptor I and p38 MAPK (show MAPK14 ELISA Kits) signaling, reduces CFTR expression to impair CFTR-mediated anion secretion, which would likely compound the effects associated with mild CFTR mutations and ultimately would compromise male fertility.

  4. The esophageal submucosal glands (SMG (show SNRPG ELISA Kits)) secrete HCO(3)(-) and mucus into the esophageal lumen, where they contribute to acid clearance and epithelial protection. We investigated the presence of CFTR, its involvement in the secretion process, and the effect of cAMP on HCO3 secretion in this tissue. This is the first report on the presence of CFTR channels in the esophagus.

  5. data suggest that loss of CFTR directly alters Schwann cell function and that some nervous system defects in people with cystic fibrosis (show S100A8 ELISA Kits) are likely primary

  6. The data suggest, that during bacterial infections and resulting release of proinflammatory cytokines, the glands are stimulated to secrete fluid, and this response is mediated by cAMP-activated CFTR.

  7. CFTR is required for maximal liquid absorption by lung alveoli under cAMP stimulation

  8. These findings reveal differences between nasal and tracheal glands, show defective fluid secretion in nasal glands of cystic fibrosis (show S100A8 ELISA Kits) pigs, reveal some spared function in the DeltaF508 vs. null piglets.

  9. causal link between CFTR mutations and partial or total vas (show AVP ELISA Kits) deferens and/or epididymis atresia at birth

  10. These data provide a molecular basis for interpreting enamel disease associated with disruptions to CFTR and AE2 (show SLC4A2 ELISA Kits) expression.

Cow (Bovine) Cystic Fibrosis Transmembrane Conductance Regulator (ATP-Binding Cassette Sub-Family C, Member 7) (CFTR) interaction partners

  1. conserved CFTR sequences between species are examined for potential regulatory elements. Regions of introns 2, 3, 10, 17a, 18, and 21 and 3' flanking sequence corresponding to human CFTR DNase I (show DNASE1 ELISA Kits) hypersensitive sites showed high homology in cow and pig.

Guinea Pig Cystic Fibrosis Transmembrane Conductance Regulator (ATP-Binding Cassette Sub-Family C, Member 7) (CFTR) interaction partners

  1. Results demonstrate functional coupling between Cftr and Slc26a6 (show SLC26A6 ELISA Kits)-like Cl(-)/HCO(3)(-) exchange activity in apical membrane of guinea pig pancreatic interlobular duct.

Cystic Fibrosis Transmembrane Conductance Regulator (ATP-Binding Cassette Sub-Family C, Member 7) (CFTR) Antigen Profile

Antigen Summary

This gene encodes a member of the ATP-binding cassette (ABC) transporter superfamily. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily that is involved in multi-drug resistance. The encoded protein functions as a chloride channel and controls the regulation of other transport pathways. Mutations in this gene are associated with the autosomal recessive disorders cystic fibrosis and congenital bilateral aplasia of the vas deferens. Alternatively spliced transcript variants have been described, many of which result from mutations in this gene.

Gene names and symbols associated with CFTR

  • cystic fibrosis transmembrane conductance regulator (cftr-A) antibody
  • cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) (CFTR) antibody
  • cystic fibrosis transmembrane conductance regulator (Cftr) antibody
  • cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) (Cftr) antibody
  • cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) (cftr) antibody
  • cystic fibrosis transmembrane conductance regulator homolog (Cftr) antibody
  • abc35 antibody
  • abcc7 antibody
  • AW495489 antibody
  • CF antibody
  • CFTR antibody
  • cftr/mrp antibody
  • dJ760C5.1 antibody
  • mrp7 antibody
  • RGD1561193 antibody
  • tnr-cftr antibody
  • xcftr antibody

Protein level used designations for CFTR

cystic fibrosis transmembrane conductance regulator , cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) , cystic fibrosis transmembrane conductance regulator, ATP-binding cassette (sub-family C, member 7) , ATP-binding cassette sub-family C member 7 , ATP-binding cassette transporter sub-family C member 7 , ATP-binding cassette, subfamily c, member 7 , cAMP-dependent chloride channel , channel conductance-controlling ATPase , cystic fibrosis transmembrane conductance regulator homolog , cystic fibrosis transmembrane conductance regulator homolog; ATP-binding cassette, subfamily c, member 7 , CFTR chloride channel , chloride channel , CFTR cAMP-dependent chloride channel protein , Channel conductance-controlling ATPase

GENE ID SPECIES
373725 Xenopus laevis
780954 Monodelphis domestica
100137161 Nomascus leucogenys
12638 Mus musculus
24255 Rattus norvegicus
1080 Homo sapiens
100049619 Gallus gallus
492302 Canis lupus familiaris
403154 Sus scrofa
281067 Bos taurus
100009471 Oryctolagus cuniculus
100719898 Cavia porcellus
100071259 Equus caballus
443347 Ovis aries
100381094 Xenopus laevis
100137035 Pongo abelii
463674 Pan troglodytes
100126675 Papio anubis
100135647 Cavia porcellus
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