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Cytochrome B Reductase 1 Proteins (CYBRD1)

CYBRD1 is a member of the cytochrome b(561) family that encodes an iron-regulated protein. Additionally we are shipping Cytochrome B Reductase 1 Antibodies (24) and Cytochrome B Reductase 1 Kits (2) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
CYBRD1 79901 Q53TN4
CYBRD1 73649 Q925G2
Rat CYBRD1 CYBRD1 295669 Q5RKJ2
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Top Cytochrome B Reductase 1 Proteins at antibodies-online.com

Showing 4 out of 4 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 49 to 54 Days
$4,244.78
Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 49 to 54 Days
$6,041.49
Details
HOST_Wheat germ Human Un-conjugated   10 μg Log in to see 9 Days
$641.43
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HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

CYBRD1 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,

Mouse (Murine)

More Proteins for Cytochrome B Reductase 1 (CYBRD1) Interaction Partners

Human Cytochrome B Reductase 1 (CYBRD1) interaction partners

  1. Polymorphisms in CYBRD1 modulates iron phenotype in HFE (show HFE Proteins) p.C282Y homozygous hemochromatosis (show HFE Proteins).

  2. Letter: report mutations in CYBRD1 promoter in and possible role in iron hemostasis in patients with porphyria cutanea tarda.

  3. In Africans with iron overload not related to the HFE (show HFE Proteins) gene, the possible involvement of the SLC40A1 (show SLC40A1 Proteins) and CYBRD1 genes was demonstrated for the first time.

  4. Duodenal cytochrome b present in human erythrocytes may contribute to their ability to reduce extracellular monodehydroascorbate.

  5. Functional characterization of Cybrd1 heme groups and iron/ascorbate metabolism.

  6. The results of this study confirm that Dcytb can act as a ferric reductase that stimulates iron uptake in Caco-2 cells.

Mouse (Murine) Cytochrome B Reductase 1 (CYBRD1) interaction partners

  1. It was concluded that Cybrd1 is the primary iron-regulated duodenal ferric reductase in the gut (show GUSB Proteins) and that it is necessary for optimal iron metabolism.

  2. Increased iron absorption reported in early hypoxia could be accounted for in part by the enhancement of Dcytb expression by Hif-2alpha (show EPAS1 Proteins) in the duodenum.

  3. Regulatory defects in liver and intestine implicate abnormal hepcidin (show HAMP Proteins) and Cybrd1 expression in hemochromatosis (show HFE Proteins).

  4. Dcytb, DMT1 (show SLC11A2 Proteins), Ireg1 (show SLC40A1 Proteins) and transferrin receptor 1 (show TFR Proteins) have roles in iron transport and hemolysis

  5. Iron absorption genes(Dcytb,IREG1 (show SLC40A1 Proteins),DMT1 (show SLC11A2 Proteins))were expressed at lower levels in mouse caecum and colon than in the duodenum. They are regulated by body iron requirements.

  6. loss of Cybrd1 had little or no impact on body iron stores, even in the setting of iron deficiency; other mechanisms must be available for the reduction of dietary iron

  7. cybrd1 is nonessential in mice

  8. Dcytb plays a physiological role in both iron and copper uptake, through divalent metal transporter 1 (DMT1 (show SLC11A2 Proteins)) and copper transporter 1 (show SLC31A1 Proteins), respectively.

Cytochrome B Reductase 1 (CYBRD1) Protein Profile

Protein Summary

This gene is a member of the cytochrome b(561) family that encodes an iron-regulated protein. It highly expressed in the duodenal brush border membrane. It has ferric reductase activity and is believed to play a physiological role in dietary iron absorption.

Gene names and symbols associated with CYBRD1

  • cytochrome b reductase 1 (cybrd1)
  • cytochrome b reductase 1 (CYBRD1)
  • cytochrome b reductase 1 (Cybrd1)
  • 2210407P13Rik protein
  • CYB561A2 protein
  • CYTB protein
  • Dcytb protein
  • FRRS3 protein
  • im:6900453 protein
  • MGC122108 protein
  • zgc:110065 protein

Protein level used designations for CYBRD1

cytochrome b reductase 1 , cytochrome b561 family, member A2 , duodenal cytochrome b , ferric-chelate reductase 3

GENE ID SPECIES
548408 Xenopus (Silurana) tropicalis
552960 Danio rerio
79901 Homo sapiens
73649 Mus musculus
478796 Canis lupus familiaris
100144591 Sus scrofa
534257 Bos taurus
295669 Rattus norvegicus
445864 Xenopus laevis
100172640 Pongo abelii
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