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anti-Cytochrome B-245, beta Polypeptide (CYBB) Antibodies

Cytochrome b (-245) is composed of cytochrome b alpha (CYBA) and beta (CYBB) chain. Additionally we are shipping CYBB Kits (5) and CYBB Proteins (5) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
CYBB 1536 P04839
CYBB 13058 Q61093
CYBB 66021  
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Top anti-CYBB Antibodies at antibodies-online.com

Showing 10 out of 94 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Chicken Rabbit Un-conjugated IHC, WB WB Suggested Anti-CYBB Antibody Titration: 1.0ug/mlELISA Titer: 1:62500Positive Control: THP-1 cell lysate IHC Information: Lung, Human: Formalin-Fixed, Paraffin-Embedded (FFPE) 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Mouse Un-conjugated WB 0.1 mL Log in to see 5 to 6 Days
$455.84
Details
Human Mouse Un-conjugated ICC, IF, IHC (p), WB 0.1 mL Log in to see 5 to 6 Days
$455.84
Details
Mouse Mouse Un-conjugated IF, WB Western blot analysis of gp91[phox] on mouse macrophage lysate. Lane 1: 1:1000, lane 2: 1:2000, lane 3: 1:4000 dilution of gp91[phox] antibody. Immunofluorescent staining of mouse macrophage cells with gp91[phox] antibody. 50 μg Log in to see 5 to 6 Days
$205.42
Details
Human Rabbit Un-conjugated IF (cc), IF (p), IHC (p), WB Formalin-fixed and paraffin embedded rat pancreas labeled with Anti NOX2/gp91phox Polyclonal Antibody, Unconjugated (ABIN750688) at 1:200 followed by conjugation to the secondary antibody and DAB staining Formalin-fixed and paraffin embedded rat brain labeled with Rabbit Anti-NOX2/gp91phox Polyclonal Antibody, Unconjugated  at 1:200 followed by conjugation to the secondary antibody and DAB staining 100 μL Log in to see 3 to 7 Days
$269.50
Details
Human Mouse Un-conjugated IHC (p), WB 0.25 mg Log in to see 6 to 8 Days
$500.50
Details
Human Rabbit Un-conjugated IHC (p), WB Anti-NOX2/gp91phox antibody, Western blotting Lane 1: HELA Cell Lysate Lane 2: JURKAT Cell Lysate Lane 3: MCF-7 Cell Lysate Lane 4: SMMC Cell Lysate Anti-NOX2/gp91phox antibody, IHC(P) IHC(P): Human Intestinal Cancer Tissue 100 μg Log in to see 4 to 6 Days
$200.00
Details
Dog Goat Un-conjugated EIA, WB AP23688PU-N (2µg/ml) staining of paraffin embedded Human Spleen. Steamed antigen retrieval with citrate buffer pH 6, HRP-staining. Anti-CYBB (0.03µg/ml) staining of Human Peripheral Blood Mononucleocytes lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 0.1 mg Log in to see 6 to 8 Days
$379.50
Details
Human Goat Un-conjugated ELISA, WB 0.1 mg Log in to see 2 to 3 Days
$433.13
Details
Human Goat Un-conjugated IHC (p) Placenta, Human: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μg Log in to see 6 to 8 Days
$500.50
Details

CYBB Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-CYBB Antibodies

  1. Mouse (Murine) Monoclonal CYBB Primary Antibody for IF, WB - ABIN968523 : Jacobsen, Skalnik: YY1 binds five cis-elements and trans-activates the myeloid cell-restricted gp91(phox) promoter. in The Journal of biological chemistry 1999 (PubMed)
    Show all 4 references for ABIN968523

  2. Human Polyclonal CYBB Primary Antibody for IF (cc), IF (p) - ABIN750688 : Dalaklioglu, Tasatargil, Kale, Tanriover, Dilmac, Erin: Metastatic breast carcinoma induces vascular endothelial dysfunction in Balb-c mice: Role of the tumor necrosis factor-? and NADPH oxidase. in Vascular pharmacology 2013 (PubMed)
    Show all 2 references for ABIN750688

  3. Human Monoclonal CYBB Primary Antibody for ICC, IF - ABIN1042596 : Burritt, Quinn, Jutila, Bond, Jesaitis: Topological mapping of neutrophil cytochrome b epitopes with phage-display libraries. in The Journal of biological chemistry 1995 (PubMed)
    Show all 2 references for ABIN1042596

  4. Human Monoclonal CYBB Primary Antibody for WB - ABIN1042597 : Baniulis, Burritt, Taylor, Dinauer, Heyworth, Parkos, Magnusson, Jesaitis: Monoclonal antibody CL5 recognizes the amino terminal domain of human phagocyte flavocytochrome b558 large subunit, gp91phox. in European journal of haematology 2005 (PubMed)

  5. Chicken Polyclonal CYBB Primary Antibody for IHC, WB - ABIN2781794 : Fink, Duval, Martel, Soucy-Faulkner, Grandvaux: Dual role of NOX2 in respiratory syncytial virus- and sendai virus-induced activation of NF-kappaB in airway epithelial cells. in Journal of immunology (Baltimore, Md. : 1950) 2008 (PubMed)

More Antibodies against CYBB Interaction Partners

Rabbit Cytochrome B-245, beta Polypeptide (CYBB) interaction partners

  1. Data indicate that NADPH oxidase (show NOX1 Antibodies) NOx2 inhibition attenuates endoplasmic reticulum (ER) stress and apoptosis.

Human Cytochrome B-245, beta Polypeptide (CYBB) interaction partners

  1. Critical role of the Mac1 (show ITGAM Antibodies)/NOX2 pathway in mediating reactive microgliosis-generated chronic neuroinflammation and progressive neurodegeneration

  2. Female patients with severe inflammatory bowel disease should be checked for X-CGD genes.

  3. Blunting of NOX2-dependent IKKepsilon (show IKBKE Antibodies) oncogenic kinase expression reduces proliferation and viability of human breast cancer cells.

  4. Furthermore, a direct interaction between AnkA and HDAC1 (show HDAC1 Antibodies) was detected at the CYBB promoter, and was critical for AnkA-mediated CYBB repression.

  5. There is a mutual enhancement between HMGB1 (show HMGB1 Antibodies) and Nox2-derived reactive oxygen species in the diabetic retina.

  6. Study reports a putative NF-kB binding site within the distant 5' fl anking region of the CYBB gene, 15 kb upstream from the transcription start site, and provide evidence for its involvement in the regulation of CYBB gene expression in human phagocytes.

  7. increased levels of gp91phox, p47phox (show NCF1 Antibodies) and p22phox (show CYBA Antibodies) likely account for the interferon-gamma (show IFNG Antibodies) mediated enhancement of dimethyl sulfoxide-induced Nox2 activity.

  8. NOX2 siRNA suppresses collagen production in primary keloid dermal fibroblasts.

  9. three cofactor independent human monoclonal aPL (show FASL Antibodies) can induce transcription of NLRP3 (show NLRP3 Antibodies) and caspase-1 (show CASP1 Antibodies) resulting in inflammasome activation specific for NLRP3 (show NLRP3 Antibodies), which depends fully on activation of endosomal NADPH-oxidase-2 (NOX2) by aPL (show FASL Antibodies)

  10. Molecular switch from NOX1 (show NOX1 Antibodies) to NOX2 in colon cancer cells induces ROS (show ROS1 Antibodies) production and subsequently enhances MMP-7 (show MMP7 Antibodies) expression by deactivating AMPK (show PRKAA1 Antibodies).

Cow (Bovine) Cytochrome B-245, beta Polypeptide (CYBB) interaction partners

  1. Data indicate that the efficiency of NADPH oxidase (show NOX1 Antibodies) enzymatic activity is higher at endoplasmic reticulum (ER).

  2. A p47(phox) and Src kinase (show CSK Antibodies) activation of peroxide production by Nox2 appears to be an important contributor to vascular contractile mechanisms mediated through activation of protein kinase C (show PKC Antibodies)

Mouse (Murine) Cytochrome B-245, beta Polypeptide (CYBB) interaction partners

  1. NADPH oxidase 2 inactivation causes regression of vascularization and the size and stability of atherosclerotic plaques

  2. Nox2 is implicated in the inflammatory and neovascular response to corneal chemical injury in mice

  3. NOX2 has a role in oxidative stress and mitochondrial abnormalities caused by saturated fat in cardiomyocytes

  4. Rnf145 implicated in proteostasis of the Nox2 complex

  5. Aging decreases prostanoid-mediated contractility in the carotid artery involving a loss of Nox2 activity and is associated with impaired endothelium-dependent, NO-mediated relaxation.

  6. eNOS (show NOS3 Antibodies) plays a key role in the regulation of expression of NOX2 and NOX4 (show NOX4 Antibodies) in the lungs exposed to hypoxia.

  7. Reactive oxygen species act as a negative feedback to constrain IL-1beta (show IL1B Antibodies)-mediated inflammation, accounting for the more severe arthritis in the absence of NOX2.

  8. This study showed the contribution of NOD2 (show NOD2 Antibodies) to inflammatory response and provided direct evidence that NOX2-mediated oxidative stress as an important target molecule linked NOD2 (show NOD2 Antibodies) to inflammatory damage in ischemic stroke.

  9. results indicate that platelet and neutrophil NOX2-produced ROS (show ROS1 Antibodies) are critical for the function of surface receptors essential for neutrophil-platelet interactions during vascular inflammation.

  10. Nox2 mRNA expression was increased in diet-induced obese (DIO) mice. Nox2 suppresses collateral vessel growth after femoral artery ligation in DIO mice.

Pig (Porcine) Cytochrome B-245, beta Polypeptide (CYBB) interaction partners

  1. sub-vasomotor concentration of ET-1 (show EDN1 Antibodies) leads to vascular dysfunction by impairing endothelium-dependent NO-mediated dilation via p38 (show MAPK14 Antibodies) kinase-mediated production of superoxide from NADPH oxidase (show NOX1 Antibodies) following ETA receptor activation

  2. Reactive oxygen species generated by NADPH oxidase (show NOX1 Antibodies) contribute to the aberrant pulmonary arterial responses in piglets exposed to 3 days of hypoxia.

  3. Upregulation of PPAR-gamma (show PPARG Antibodies) and NADPH (show NQO1 Antibodies) oxidases are involved in restenosis.

CYBB Antigen Profile

Protein Summary

Cytochrome b (-245) is composed of cytochrome b alpha (CYBA) and beta (CYBB) chain. It has been proposed as a primary component of the microbicidal oxidase system of phagocytes. CYBB deficiency is one of five described biochemical defects associated with chronic granulomatous disease (CGD). In this disorder, there is decreased activity of phagocyte NADPH oxidase\; neutrophils are able to phagocytize bacteria but cannot kill them in the phagocytic vacuoles. The cause of the killing defect is an inability to increase the cell's respiration and consequent failure to deliver activated oxygen into the phagocytic vacuole.

Gene names and symbols associated with CYBB

  • cytochrome b-245, beta polypeptide (chronic granulomatous disease) (cybb) antibody
  • cytochrome b-245, beta polypeptide (cybb) antibody
  • cytochrome b-245, beta polypeptide (chronic granulomatous disease) (CYBB) antibody
  • cytochrome b-245, beta polypeptide (CYBB) antibody
  • cytochrome b-245 beta polypeptide (CYBB) antibody
  • cytochrome b-245, beta polypeptide (Cybb) antibody
  • NADPH oxidase heavy chain subunit (GP91-PHOX) antibody
  • AMCBX2 antibody
  • C88302 antibody
  • Cgd antibody
  • CGD91-phox antibody
  • CYBB antibody
  • Cyd antibody
  • GP91-1 antibody
  • Gp91-phox antibody
  • GP91PHOX antibody
  • NOX1 antibody
  • Nox2 antibody
  • p91-PHOX antibody
  • zgc:64144 antibody

Protein level used designations for CYBB

cytochrome b-245, beta polypeptide , gp91 , NADPH oxidase 2 , cytochrome b-245, beta polypeptide (chronic granulomatous disease) , Cytochrome b-245 heavy chain , NADPH oxidase heavy chain subunit , NADPH oxidase 1 , NADPH oxidase flavocytochrome b subunit , cytochrome b-245 heavy chain , gp91-phox , CGD91-phox , cytochrome b(558) subunit beta , cytochrome b558 subunit beta , heme-binding membrane glycoprotein gp91phox , neutrophil cytochrome b 91 kDa polypeptide , p22 phagocyte B-cytochrome , superoxide-generating NADPH oxidase heavy chain subunit , gp91-1 , endothelial type gp91-phox , predicted NADPH oxidase-2

GENE ID SPECIES
393386 Danio rerio
595081 Xenopus (Silurana) tropicalis
696542 Macaca mulatta
444353 Xenopus laevis
100036757 Ovis aries
100270807 Salmo salar
100008801 Oryctolagus cuniculus
1536 Homo sapiens
418581 Gallus gallus
281112 Bos taurus
13058 Mus musculus
66021 Rattus norvegicus
491825 Canis lupus familiaris
397108 Sus scrofa
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