Cytochrome B5 Type A (Microsomal) (CYB5A) ELISA Kits

The protein encoded by CYB5A is a membrane-bound cytochrome that reduces ferric hemoglobin (methemoglobin) to ferrous hemoglobin, which is required for stearyl-CoA-desaturase activity. Additionally we are shipping Cytochrome B5 Type A (Microsomal) Antibodies (106) and Cytochrome B5 Type A (Microsomal) Proteins (15) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
CYB5A 109672 P56395
CYB5A 1528 P00167
CYB5A 64001 P00173
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Top Cytochrome B5 Type A (Microsomal) ELISA Kits at antibodies-online.com

Showing 10 out of 28 products:

Catalog No. Reactivity Sensitivity Range Images Quantity Supplier Delivery Price Details
Human 5.8 pg/mL 23.5-1500 pg/mL Typical standard curve 96 Tests Log in to see 15 to 18 Days
$910.56
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Human 0.078 ng/mL 0.156-10 ng/mL   96 Tests Log in to see 2 to 3 Days
$658.90
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Dog 0.1 ng/mL 1.0-25 ng/mL   96 Tests Log in to see 15 to 18 Days
$707.14
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Mouse 9.4 pg/mL 15.6-1000 pg/mL   96 Tests Log in to see 13 to 16 Days
$436.50
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Rabbit
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$707.14
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Guinea Pig
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$707.14
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Pig
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$707.14
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Goat
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$707.14
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Cow
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$707.14
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Monkey
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$707.14
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More ELISA Kits for Cytochrome B5 Type A (Microsomal) Interaction Partners

Mouse (Murine) Cytochrome B5 Type A (Microsomal) (CYB5A) interaction partners

  1. Demonstration of the physiologic importance of cytochrome b5 activating the 17,20-lyase reaction and the production of 19-carbon sex steroids from 21-carbon precursors in mice.

  2. Cytochrome b5 and cytokeratin 17 (show KRT17 ELISA Kits) are biomarkers in bronchoalveolar fluid signifying onset of acute lung injury.

Rabbit Cytochrome B5 Type A (Microsomal) (CYB5A) interaction partners

  1. Data indicate not only that binding of b5 and P450 reductase (show POR ELISA Kits) on the proximal surface of P450 (show POR ELISA Kits) 2B4 (show CD244 ELISA Kits) results in electron transfer but also that each redox partner transmits unique structural information to the active site proton delivery network.

  2. the observation of weak and nonspecific interactions between CYP2B4 and cytb5 in micelles suggests that lipid bilayer structures and low curvature membrane surface are preferable for CYP2B4-cytb5 complex formation.

  3. Data suggest that the cytb5-cytP4502B4 complex structure will help unravel the mechanism by which cytb5 regulates catalysis by cytP4502B4.

  4. Two different types of cytochrome b5 orientations are present within a MFO system: the first allowing potential cytochrome b5 electron donation to P450 (show POR ELISA Kits), the second one inducing cytochrome b5 modulation of P450 (show POR ELISA Kits) structural changes.

Human Cytochrome B5 Type A (Microsomal) (CYB5A) interaction partners

  1. Data suggest CYP17A1 (show CYP17A1 ELISA Kits), with electron donor NADPH-P450 reductase (show POR ELISA Kits), is inherently distributive enzyme but that some processivity is present; some 17alpha-hydroxy pregnenolone formed does not dissociate from CYP17A1 (show CYP17A1 ELISA Kits) before conversion to dehydroepiandrosterone; CYB5A does not enhance reaction by decreasing k(off) of ligands of CYP17A1 (show CYP17A1 ELISA Kits). (CYP17A1 (show CYP17A1 ELISA Kits) = cytochrome P450 (show CYP ELISA Kits), family 17, subfamily A (show CYP ELISA Kits), polypeptide 1 (show CYP ELISA Kits); CYB5A = cytochrome b5)

  2. Data suggest that cytochrome b5 (CYB5) and cytochrome b5 reductase 3 (CYB5R3 (show CYB5R3 ELISA Kits)) can reduce human cytoglobin (CYGB (show CYGB ELISA Kits)) and zebrafish cytoglobins at rates up to 250-fold higher than those reported for the known physiological substrates, hemoglobin (show HBB ELISA Kits) and myoglobin (show MB ELISA Kits); the three proteins (CYB5+CYB5R3 (show CYB5R3 ELISA Kits)+CYGB (show CYGB ELISA Kits)) appear to constitute a metabolon involved in generation of nitric oxide.

  3. Thus, although Mn-b5 binds to CYP17A1 (show CYP17A1 ELISA Kits), it is unable to enhance the lyase reaction, strongly suggesting that cyt b5 has a redox effector role in enhancement of the CYP17A1 (show CYP17A1 ELISA Kits) mediated lyase reaction necessary for androgen synthesis.

  4. This study constructed a model of the membrane-bound full-length human P450 1A2-cyt b5 complex. The model was assembled from several parts using a multiscale modeling approach covering all-atom and coarse-grained molecular dynamics (MD).

  5. We conclude that cytochrome b5 can influence the electronic conductivity of cytochrome P450c17 (show CYP17A1 ELISA Kits) via allosteric, protein-protein interactions.

  6. Variants in CYB5A and CYB5R3 (show CYB5R3 ELISA Kits) should be considered in the evaluation of breast cancer risk in African American women.

  7. CYB5A is the first RA susceptibility gene involved in androgen synthesis. Our functional analysis of SNP rs1790834 indicates that it contributes to the sex bias observed in RA.

  8. both area and ratio of 3betaHSD (show HSD3B1 ELISA Kits) and CYB5A double positive cells, which could represent the hybrid cells of zona fasciculate and zona reticularis, are correlated with adrenal development and could influence age-related serum androstenedione levels.

  9. Two acidic residues, Glu (show DCTN1 ELISA Kits)-48 and Glu (show DCTN1 ELISA Kits)-49, of cytochrome b5 are essential for stimulating the 17,20-lyase activity of CYP17A1 (show CYP17A1 ELISA Kits).

  10. raises the possibility that inhibition of CYB5A-deregulated downstream pathways, such as those involving TRAF6 (show TRAF6 ELISA Kits), may favor autophagy-mediated cancer cell death in selected subgroups of patients

Pig (Porcine) Cytochrome B5 Type A (Microsomal) (CYB5A) interaction partners

  1. Searching the porcine CYB5 gene for mutations, examine its expression, and identify genetic polymorphism in terms of androstenone levels in testis.

  2. the c.-8G>T SNP in the CYB5A gene has a significant but modest effect on boar taint in male pigs and could be useful in some breeds as part of a panel of SNP markers in a marker-assisted selection programme to produce low boar taint pigs

  3. These results demonstrate the differential effects of two forms of CYB5 on the three activities of porcine CYP17A1 (show CYP17A1 ELISA Kits) and show that CYB5B (show CYB5B ELISA Kits) does not stimulate the andien-beta synthase activity of CYP17A1 (show CYP17A1 ELISA Kits).

Cow (Bovine) Cytochrome B5 Type A (Microsomal) (CYB5A) interaction partners

  1. The study computes electron transfer rates for the [myoglobin (show MB ELISA Kits)(wt), cytochrome b5] complex.

  2. The solution structure of the oxidized cytochrome b(5) mutant V61H.

  3. the effects on the heme microenvironment of cytochrome b(5) caused by the mutation from Val45 to Tyr45, His45 and Glu45

  4. Results from three combined experiments demonstrate that the conserved negatively charged region of cytb5 surrounding the solvent-exposed heme edge is involved in the binding interaction with horse heart cytochrome c (show CYCS ELISA Kits).

  5. From a series of site-directed mutations on Cyt b5 this report assesses the contributions of amino acid residues that are expected to influence the docking and electron transfer (ET) between Cyt b5 and horse heart Cyt c (show CYCS ELISA Kits).

  6. simulations provided qualitative microscopic explanations of many of the differences in physical properties between outer mitochondrial membrane CYB5 isoform and microsomal CYB5 and two mutants in terms of localized changes in structure and flexibility

Horse (Equine) Cytochrome B5 Type A (Microsomal) (CYB5A) interaction partners

  1. It was concluded that CYP3A related metabolism in horse is not solely dependent on the expression of the enzyme but also on adequate levels of NADPH P450 reductase (show POR ELISA Kits) and cytochrome b(5).

Cytochrome B5 Type A (Microsomal) (CYB5A) Antigen Profile

Antigen Summary

The protein encoded by this gene is a membrane-bound cytochrome that reduces ferric hemoglobin (methemoglobin) to ferrous hemoglobin, which is required for stearyl-CoA-desaturase activity. Defects in this gene are a cause of type IV hereditary methemoglobinemia. Three transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with CYB5A

  • cytochrome b5 type A (microsomal) (cyb5a) antibody
  • cytochrome b-5 (Cyb5) antibody
  • cytochrome b5 (LOC100328915) antibody
  • cytochrome b5 (CYB5A) antibody
  • cytochrome b5 type A (microsomal) (CYB5A) antibody
  • cytochrome b5 type A (microsomal) (Cyb5a) antibody
  • cytochrome b5-like (LOC100735904) antibody
  • 0610009N12Rik antibody
  • Cyb5 antibody
  • CYB5A antibody
  • MCB5 antibody
  • MGC80327 antibody
  • wu:fb44a11 antibody
  • zgc:64123 antibody

Protein level used designations for CYB5A

cytochrome b5 , cytochrome b5 type A (microsomal) , type 1 cyt-b5 , cytochrome b-5 , cytochrome b5A microsomal

GENE ID SPECIES
406409 Danio rerio
446542 Xenopus laevis
548733 Xenopus (Silurana) tropicalis
109672 Mus musculus
100328915 Oryctolagus cuniculus
100861011 Capra hircus
1528 Homo sapiens
64001 Rattus norvegicus
476167 Canis lupus familiaris
414799 Sus scrofa
281110 Bos taurus
100335454 Bos taurus
414798 Gallus gallus
100052210 Equus caballus
100307037 Ovis aries
100735904 Cavia porcellus
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