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Cytochrome P450, Family 1, Subfamily A, Polypeptide 1 Proteins (CYP1A1)

CYP1A1, CYP1A1, encodes a member of the cytochrome P450 superfamily of enzymes. Additionally we are shipping CYP1A1 Antibodies (122) and CYP1A1 Kits (30) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
CYP1A1 1543 P04798
CYP1A1 24296 P00185
CYP1A1 13076 P00184
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Top CYP1A1 Proteins at antibodies-online.com

Showing 9 out of 9 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human His tag,T7 tag 100 μg Log in to see 11 to 13 Days
$844.80
Details
HOST_Escherichia coli (E. coli) Mouse His tag,T7 tag 100 μg Log in to see 11 to 13 Days
$897.60
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
$3,488.83
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   100 μg Log in to see 9 to 19 Days
$1,014.95
Details
HOST_Escherichia coli (E. coli) Mouse Un-conjugated   100 μg Log in to see 9 to 19 Days
$1,062.16
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

CYP1A1 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
, ,
Rat (Rattus)

Mouse (Murine)
,

More Proteins for Cytochrome P450, Family 1, Subfamily A, Polypeptide 1 (CYP1A1) Interaction Partners

Pig (Porcine) Cytochrome P450, Family 1, Subfamily A, Polypeptide 1 (CYP1A1) interaction partners

  1. There was no association between CYP1A1 C genotype and survival in the overall study population

  2. The effect of human chorionic gonadotropin on the activities of cytochrome P-450 CYP1A1, cytochrome P-450 CYP2B1 and methoxyresorufin O-demethylase (MROD) was studied in intact male pigs of 2 breeds.[CYP2B1; MROD]

  3. This study demonstrated for the first time that the serum testosterone level is one of the physiological factors which regulate constitutive expression of hepatic CYP1A1 and CYP1A2 (show CYP1A2 Proteins) in pigs.

  4. The findings demonstrate a gender-related difference in the constitutive expression of hepatic CYP1A1 in Meishan pigs and further indicate that testosterone down-regulates the constitutive gene expression of the enzyme.

  5. Distinct subtypes of urinary bladder epithelial cells with inducible and non-inducible cytochrome P-450 CYP1A1 are reported.

  6. Effect of beta-napthoflavone on AHR (show AHR Proteins)-related gene, CYP1A1, in the pig is reported.

Human Cytochrome P450, Family 1, Subfamily A, Polypeptide 1 (CYP1A1) interaction partners

  1. polymorphisms in CYP2E1 (show CYP2E1 Proteins) (PstI (show SPINK1 Proteins)) and CYP1A1 (MspI) were not associated with sporadic colorectal cancer in the evaluated Brazilian population.

  2. A significant association between the frequency of the CYP1A1 polymorphism and the development of cervical cancer.

  3. CYP1A1 and GSTM1 (show GSTM1 Proteins) gene polymorphisms affect familial aggregation of esophageal cancer among the Kazakh ethnic group in Xinjiang.

  4. the association of CYP1A1 M1 (rs4646903) and COMT (show COMT Proteins) (rs4680) polymorphisms in 130 cervical cancer cases (c-cancer) and 179 controls, is reported.

  5. Data show a combined role of cytochrome P 450 1A1 (show SLC45A2 Proteins) (CYP1A1), Glutathione -S -transferase M1 (GSTM1 (show GSTM1 Proteins)) and T1 (GSTT1 (show GSTT1 Proteins)) polymorphisms and smoking status can be attributed for the cause of lung cancer.

  6. The allelic variation frequency of the CYP1A1 gene at exon 7 (Ile 462 Val) in bone tumor patients was significantly higher than that in control.

  7. CYP1A1 expression in 3D spheroids of liver cancer cells is regulated by AhR (show AHR Proteins) and PXR (show NR1I2 Proteins).

  8. The CYP1A1 gene deletion is a lung cancer risk factor, and interacts with smoking in non-small cell lung cancer development.

  9. The result indicates that the risk of Head and Neck Cancer associated with tobacco and alcohol is modulated by CYP1A1 T3801C polymorphism.

  10. the association between CYP1A1 polymorphisms and chronic obstructive pulmonary disease risk, is reported.

Mouse (Murine) Cytochrome P450, Family 1, Subfamily A, Polypeptide 1 (CYP1A1) interaction partners

  1. Taken together, CAPE decreases 3-MC-mediated CYP1A1 expression, and this inhibitory response is associated with inhibition of AhR (show AHR Proteins) and HIF-1alpha (show HIF1A Proteins) induction.

  2. Our results support the hypothesis that CYP1A1 protects against hyperoxic lung injury by decreasing oxidative stress.

  3. CYP1A1 contributes to nitric oxide bioavailability and blood pressure regulation mediated by dietary omega-3 polyunsaturated fatty acids.

  4. Aryl hydrocarbon receptor (show AHR Proteins) mediated induction of hepatic CYP1A1/1A2 is dependent on the presence of ctnnb1 (show CTNNB1 Proteins).

  5. Suggest that CYP1A induction by coplanar polychlorinated/brominated biphenyls depends on AhR (show AHR Proteins) transcriptional activity and not on AhR (show AHR Proteins) expression.

  6. Identify hepatic proteins necessary for the AHR (show AHR Proteins)-dependent induction of CYP1A1 by 2,3,7,8-tetrachlorodibenzo-p-dioxin.

  7. In livers of HRN mice Cyp1a1, cytochrome b5 (show CYB5A Proteins) and mEH (show EPHX1 Proteins) can effectively activate BaP (show PHB2 Proteins) to DNA binding species, even in the presence of very low amounts of P450 (show POR Proteins) oxidoreductase (show HSD17B6 Proteins).

  8. Reactive oxygen species production contributes to benzo[a]pyrene (BaP (show PHB2 Proteins))-exacerbated atherosclerosis and CYP1A1 plays a protective role against oral BaP (show PHB2 Proteins) toxicity in aorta

  9. harmine and harmaline are promising candidate to inhibit TCDD-mediated induction of Cyp1a1 in mice hepatic and extrahepatic tissues

  10. Regular consumption of green and white tea exerted protection against benzo(a)pyrene induced toxicity as it modulates the CYP1B1 (show CYP1B1 Proteins), CYP1A1 enzymes, resulting in reduction of BaPDE-DNA adducts formation.

Rabbit Cytochrome P450, Family 1, Subfamily A, Polypeptide 1 (CYP1A1) interaction partners

  1. CYP1A1 and CYP1A2 (show CYP1A2 Proteins) localization into different lipid microdomains is governed by their N-terminal and internal protein regions

CYP1A1 Protein Profile

Protein Summary

This gene, CYP1A1, encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by some polycyclic aromatic hydrocarbons (PAHs), some of which are found in cigarette smoke. The enzyme's endogenous substrate is unknown\; however, it is able to metabolize some PAHs to carcinogenic intermediates. The gene has been associated with lung cancer risk. A related family member, CYP1A2, is located approximately 25 kb away from CYP1A1 on chromosome 15.

Gene names and symbols associated with CYP1A1

  • cytochrome P450, family 1, subfamily A, polypeptide 1 (CYP1A1)
  • cytochrome P450 1A1 (CYPIA1)
  • cytochrome P450 1A1 (CpipJ_CPIJ010542)
  • cytochrome P450 1A1 (cyp1a1)
  • cytochrome P450 1A1 (CYP1A1)
  • cytochrome P450, family 1, subfamily a, polypeptide 1 (Cyp1a1)
  • cytochrome P4501A1 (CYP1A1)
  • polycyclic hydrocarbon-inducible cytochrome P450c (LOC100328613)
  • AHH protein
  • AHRR protein
  • CP11 protein
  • CYP1 protein
  • CYP1A1 protein
  • Cyp1a2 protein
  • Cyp45c protein
  • Cypc45c protein
  • CYPIA1 protein
  • P-450MC protein
  • P1-450 protein
  • P450-1 protein
  • P450-C protein
  • P450DX protein

Protein level used designations for CYP1A1

cytochrome P450 1A1 , CYPIA1 , cytochrome P450 CYP1A1 , aryl hydrocarbon hydroxylase , cytochrome P1-450, dioxin-inducible , cytochrome P450 form 6 , cytochrome P450, subfamily I (aromatic compound-inducible), polypeptide 1 , cytochrome P450-C , cytochrome P450-P1 , flavoprotein-linked monooxygenase , xenobiotic monooxygenase , P450MT2 , P450form6 , cytochrome P1-450 , cytochrome P450 subfamily I (aromatic compound-inducible) member A1 (C6 form c) (C6 form c) , cytochrome P450, 1a1 , cytochrome P450, subfamily I (aromatic compound-inducible), member A1 (C6, form c) (C6, form c) , cytochrome P450MT2 , dioxin-inducible , microsomal monooxygenase , aromatic compound inducible , cytochrome P450 family 1 subfamily a polypeptide 2 , cytochrome P450 subfamily I, polypeptide 1 , cytochrome P450, 1a1, aromatic compound inducible , P-450 PHPAH1 , P450 LM6 , P450 isozyme 6 , cytochrome P-450 PHPAH1 , cytochrome P450 LM6 , cytochrome P450 isozyme 6

GENE ID SPECIES
678694 Macaca mulatta
704920 Macaca mulatta
6043063 Culex quinquefasciatus
100020715 Monodelphis domestica
100062285 Equus caballus
100145341 Xenopus (Silurana) tropicalis
403103 Sus scrofa
554347 Felis catus
1543 Homo sapiens
24296 Rattus norvegicus
13076 Mus musculus
100686778 Canis lupus familiaris
100135512 Cavia porcellus
100170113 Ovis aries
100328613 Oryctolagus cuniculus
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