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Cytochrome P450, Family 1, Subfamily A, Polypeptide 1 Proteins (CYP1A1)

CYP1A1, CYP1A1, encodes a member of the cytochrome P450 superfamily of enzymes. Additionally we are shipping CYP1A1 Antibodies (128) and CYP1A1 Kits (23) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
CYP1A1 1543 P04798
CYP1A1 24296 P00185
CYP1A1 13076 P00184
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Top CYP1A1 Proteins at antibodies-online.com

Showing 9 out of 9 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human His tag,T7 tag 100 μg Log in to see 11 to 13 Days
$844.80
Details
HOST_Escherichia coli (E. coli) Mouse His tag,T7 tag 100 μg Log in to see 11 to 13 Days
$897.60
Details
HOST_Wheat germ Human GST tag 2 μg Log in to see 9 Days
$246.96
Details
Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
$3,488.83
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   100 μg Log in to see 9 to 16 Days
$886.88
Details
HOST_Escherichia coli (E. coli) Mouse Un-conjugated   100 μg Log in to see 9 to 16 Days
$928.13
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

CYP1A1 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
, ,
Rat (Rattus)

Mouse (Murine)
,

More Proteins for Cytochrome P450, Family 1, Subfamily A, Polypeptide 1 (CYP1A1) Interaction Partners

Pig (Porcine) Cytochrome P450, Family 1, Subfamily A, Polypeptide 1 (CYP1A1) interaction partners

  1. Significant CYP1A1 expression increases over control animals was observed in ileum tissue in swine exposed to a single dose of 10 mgkg-bw-1 PAHs

  2. There was no association between CYP1A1 C genotype and survival in the overall study population

  3. The effect of human chorionic gonadotropin on the activities of cytochrome P-450 CYP1A1, cytochrome P-450 CYP2B1 and methoxyresorufin O-demethylase (MROD) was studied in intact male pigs of 2 breeds.[CYP2B1; MROD]

  4. This study demonstrated for the first time that the serum testosterone level is one of the physiological factors which regulate constitutive expression of hepatic CYP1A1 and CYP1A2 (show CYP1A2 Proteins) in pigs.

  5. The findings demonstrate a gender-related difference in the constitutive expression of hepatic CYP1A1 in Meishan pigs and further indicate that testosterone down-regulates the constitutive gene expression of the enzyme.

  6. Distinct subtypes of urinary bladder epithelial cells with inducible and non-inducible cytochrome P-450 CYP1A1 are reported.

  7. Effect of beta-napthoflavone on AHR (show AHR Proteins)-related gene, CYP1A1, in the pig is reported.

Human Cytochrome P450, Family 1, Subfamily A, Polypeptide 1 (CYP1A1) interaction partners

  1. Mixed-ligand copper(II) complexes activate AhR (show AHR Proteins) and induce AhR (show AHR Proteins)-dependent CYP (show PPIG Proteins)!a1/2 genes in human hepatocytes.

  2. Metabolism of amiodarone to desethylamiodarone by CYP1A1 or CYP3A4 (show CYP3A4 Proteins) plays an important role in the hepatocellular toxicity of amiodarone.

  3. Results of the present study might be important in understanding the distribution of CYP1A1 (m1) and CYP1A1 (m2) polymorphisms in Mazandaran province of Iran.

  4. The aim of this work is to review the origin, regulation, and structural and functional characteristics of CYP1A1 letting us understand its role in the bioactivation of precarcinogen and the consequences of its modulation in other physiological processes, as well as guide us in the study of this important protein.

  5. the CYP1A1 mRNA levels increased with the greatest effect at 100 nM of FICZ. The AhR (show AHR Proteins) protein levels significantly decreased as the FICZ concentration increased. Additionally, the CYP1A1 protein levels were notably increased

  6. Gene polymorphism of CYP1A1 at NcoI site was observed to be significantly higher.

  7. A positive relationship was identified between CYP1A1 mRNA levels and the presence of chronic disease.

  8. Study shows that the risk of developing hepatocellular carcinoma in Egyptian population can be partly explained by genetic polymorphisms in GSTP1 (show GSTP1 Proteins) gene.

  9. CYP1A1 rs1048943 and rs4646903 polymorphisms contribute to risk of laryngeal cancer.

  10. Resulted in transient CYP1A1 and CYP1A2 (show CYP1A2 Proteins) mRNA accumulations.

Mouse (Murine) Cytochrome P450, Family 1, Subfamily A, Polypeptide 1 (CYP1A1) interaction partners

  1. Taken together, CAPE decreases 3-MC-mediated CYP1A1 expression, and this inhibitory response is associated with inhibition of AhR (show AHR Proteins) and HIF-1alpha (show HIF1A Proteins) induction.

  2. Our results support the hypothesis that CYP1A1 protects against hyperoxic lung injury by decreasing oxidative stress.

  3. CYP1A1 contributes to nitric oxide bioavailability and blood pressure regulation mediated by dietary omega-3 polyunsaturated fatty acids.

  4. Aryl hydrocarbon receptor (show AHR Proteins) mediated induction of hepatic CYP1A1/1A2 is dependent on the presence of ctnnb1 (show CTNNB1 Proteins).

  5. Suggest that CYP1A induction by coplanar polychlorinated/brominated biphenyls depends on AhR (show AHR Proteins) transcriptional activity and not on AhR (show AHR Proteins) expression.

  6. Identify hepatic proteins necessary for the AHR (show AHR Proteins)-dependent induction of CYP1A1 by 2,3,7,8-tetrachlorodibenzo-p-dioxin.

  7. In livers of HRN mice Cyp1a1, cytochrome b5 (show CYB5A Proteins) and mEH (show EPHX1 Proteins) can effectively activate BaP (show PHB2 Proteins) to DNA binding species, even in the presence of very low amounts of P450 (show POR Proteins) oxidoreductase (show HSD17B6 Proteins).

  8. Reactive oxygen species production contributes to benzo[a]pyrene (BaP (show PHB2 Proteins))-exacerbated atherosclerosis and CYP1A1 plays a protective role against oral BaP (show PHB2 Proteins) toxicity in aorta

  9. harmine and harmaline are promising candidate to inhibit TCDD-mediated induction of Cyp1a1 in mice hepatic and extrahepatic tissues

  10. Regular consumption of green and white tea exerted protection against benzo(a)pyrene induced toxicity as it modulates the CYP1B1 (show CYP1B1 Proteins), CYP1A1 enzymes, resulting in reduction of BaPDE-DNA adducts formation.

Rabbit Cytochrome P450, Family 1, Subfamily A, Polypeptide 1 (CYP1A1) interaction partners

  1. CYP1A1 and CYP1A2 (show CYP1A2 Proteins) localization into different lipid microdomains is governed by their N-terminal and internal protein regions

CYP1A1 Protein Profile

Protein Summary

This gene, CYP1A1, encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by some polycyclic aromatic hydrocarbons (PAHs), some of which are found in cigarette smoke. The enzyme's endogenous substrate is unknown\; however, it is able to metabolize some PAHs to carcinogenic intermediates. The gene has been associated with lung cancer risk. A related family member, CYP1A2, is located approximately 25 kb away from CYP1A1 on chromosome 15.

Gene names and symbols associated with CYP1A1

  • cytochrome P450, family 1, subfamily A, polypeptide 1 (CYP1A1)
  • cytochrome P450 1A1 (CYPIA1)
  • cytochrome P450 1A1 (CpipJ_CPIJ010542)
  • cytochrome P450 1A1 (cyp1a1)
  • cytochrome P450 1A1 (CYP1A1)
  • cytochrome P450, family 1, subfamily a, polypeptide 1 (Cyp1a1)
  • cytochrome P4501A1 (CYP1A1)
  • polycyclic hydrocarbon-inducible cytochrome P450c (LOC100328613)
  • AHH protein
  • AHRR protein
  • CP11 protein
  • CYP1 protein
  • CYP1A1 protein
  • Cyp1a2 protein
  • Cyp45c protein
  • Cypc45c protein
  • CYPIA1 protein
  • P-450MC protein
  • P1-450 protein
  • P450-1 protein
  • P450-C protein
  • P450DX protein

Protein level used designations for CYP1A1

cytochrome P450 1A1 , CYPIA1 , cytochrome P450 CYP1A1 , aryl hydrocarbon hydroxylase , cytochrome P1-450, dioxin-inducible , cytochrome P450 form 6 , cytochrome P450, subfamily I (aromatic compound-inducible), polypeptide 1 , cytochrome P450-C , cytochrome P450-P1 , flavoprotein-linked monooxygenase , xenobiotic monooxygenase , P450MT2 , P450form6 , cytochrome P1-450 , cytochrome P450 subfamily I (aromatic compound-inducible) member A1 (C6 form c) (C6 form c) , cytochrome P450, 1a1 , cytochrome P450, subfamily I (aromatic compound-inducible), member A1 (C6, form c) (C6, form c) , cytochrome P450MT2 , dioxin-inducible , microsomal monooxygenase , aromatic compound inducible , cytochrome P450 family 1 subfamily a polypeptide 2 , cytochrome P450 subfamily I, polypeptide 1 , cytochrome P450, 1a1, aromatic compound inducible , P-450 PHPAH1 , P450 LM6 , P450 isozyme 6 , cytochrome P-450 PHPAH1 , cytochrome P450 LM6 , cytochrome P450 isozyme 6

GENE ID SPECIES
678694 Macaca mulatta
704920 Macaca mulatta
6043063 Culex quinquefasciatus
100020715 Monodelphis domestica
100062285 Equus caballus
100145341 Xenopus (Silurana) tropicalis
403103 Sus scrofa
554347 Felis catus
1543 Homo sapiens
24296 Rattus norvegicus
13076 Mus musculus
100686778 Canis lupus familiaris
100135512 Cavia porcellus
100170113 Ovis aries
100328613 Oryctolagus cuniculus
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