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Cytochromes P450 are a group of heme-thiolate monooxygenases.
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Human Monoclonal CYP1A1/2 Primary Antibody for ICC, IF - ABIN261502
Volková, Forstová-Krízová, Skálová, Trejtnar: Modulatory effects of quercetin and rutin on the activity, expression and inducibility of CYP1A1 in intestinal HCT-8 cells. in Phytotherapy research : PTR 2014
our results suggest a more important contribution of CYP1A2 (show CYP1A1 Antibodies) to the in vivo plasma clearance and thus detoxification of 4-Aminobiphenyl
hepatic CYP1A2 (show CYP1A1 Antibodies) plays a critical role in the attenuation of hyperoxic lung injury by decreasing lipid peroxidation and oxidative stress in vivo.
Aryl hydrocarbon receptor (show AHR Antibodies) mediated induction of hepatic CYP1A1 (show CYP1A1 Antibodies)/1A2 is dependent on the presence of ctnnb1 (show CTNNB1 Antibodies).
Results indicate Cyp1a2 (show CYP1A1 Antibodies) genotype is important in susceptibility to PCB (show PC Antibodies)-induced deficits in learning and memory.
Miroestrol and deoxymiroestrol significantly up-regulated CYP2B9 while suppressing CYP1A2 (show CYP1A1 Antibodies) at both transcriptional and enzymatic levels.
A report of uroporphyria development in Cyp1a2 (show CYP1A1 Antibodies)-/- mice additionally null for both alleles of the hemochromatosis (Hfe (show HFE Antibodies)) gene and heterozygous for deletion of the uroporphyrinogen decarboxylase (Urod (show UROD Antibodies)) gene (genotype: Cyp1a2 (show CYP1A1 Antibodies)-/-;Hfe (show HFE Antibodies)-/-;Urod (show UROD Antibodies)+/-).
High levels of maternal hepatic CYP1A2 (show CYP1A1 Antibodies) protect against deficits in learning and memory in offspring exposed to a mixture of coplanar and noncoplanar PCBs; high-affinity AHR (show AHR Antibodies) is the next most important factor in protection of offspring.
In rodents, aristolochic acid demethylation, mediated by CYP1A2 (show CYP1A1 Antibodies), is a primary pathway of aristolochic acid detoxication.
The expression of Cyp1a1 (show CYP1A1 Antibodies), Cyp1a2 (show CYP1A1 Antibodies), and OGG1genes was significantly up-regulated in mice given diets containing 375 ppm dicyclanil or more.
the TRE (show TREH Antibodies) element in E1 is essential for constitutive expression of the mouse Cypla2 gene
Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics. Most active in catalyzing 2-hydroxylation (By similarity).
, aromatic compound inducible
, cytochrome P450 1A2
, cytochrome P450 family 1 subfamily a polypeptide 1
, cytochrome P450, 1a2, aromatic compound inducible
, cytochrome P450-P2
, cytochrome P450-P3