anti-Cytochrome P450, Family 1, Subfamily A, Polypeptide 2 (CYP1A2) Antibodies

CYP1A2 encodes a member of the cytochrome P450 superfamily of enzymes. Additionally we are shipping CYP1A2 Kits (34) and CYP1A2 Proteins (10) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
CYP1A2 1544 P05177
CYP1A2 13077 P00186
CYP1A2 24297 P04799
How to order from antibodies-online
  • +1 877 302 8632
  • +1 888 205 9894 (toll-free)
  • Order online
  • orders@antibodies-online.com

Top anti-CYP1A2 Antibodies at antibodies-online.com

Showing 10 out of 189 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated IF (p), IHC (p), WB Formalin-fixed and paraffin embedded rat liver labeled with Anti-P450 1A2/CYP1A2 Polyclonal Antibody, Unconjugated (ABIN742470) followed by conjugation to the secondary antibody and DAPI staining Formalin-fixed and paraffin embedded rat liver labeled with Anti-P450 1A2/CYP1A2 Polyclonal Antibody, Unconjugated (ABIN742470) at 1:200 followed by conjugation to the secondary antibody and DAB staining 100 μL Log in to see 3 to 7 Days
$295.90
Details
Human Rabbit Un-conjugated IHC (p), WB Anti- CYP1A2 Picoband antibody, IHC(P) IHC(P): Human Liver Cancer Tissue Anti- CYP1A2 Picoband antibody, IHC(P) IHC(P): Mouse Liver Tissue 100 μg Log in to see 4 to 6 Days
$240.00
Details
Human Rabbit Un-conjugated IHC, ELISA Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue, using Cytochrome P450 1A2 Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Mouse Goat Un-conjugated ELISA, WB Western Blot: Cytochrome P450 1A2 Antibody [NBP1-97780] - (1ug/ml) Analysis of fetal Mouse Liver lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. Western Blot: Cytochrome P450 1A2 Antibody  - staining of Human Liver (A) and (1ug/ml) Lung (B) lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 0.1 mg Log in to see 7 to 9 Days
$408.19
Details
Human Rabbit Un-conjugated IHC (p), WB Anti-Cytochrome P450 1A2 antibody, IHC(P) IHC(P): Rat Liver Tissue Anti-Cytochrome P450 1A2 antibody, Western blotting Lane 1: Rat Liver Tissue Lysate Lane 2: Rat Liver Tissue Lysate Lane 3: SMMC Cell Lysate Lane 4: HEPA Cell Lysate 100 μg Log in to see 4 to 6 Days
$200.00
Details
Human Rabbit Un-conjugated EIA, IF, IHC (p), WB   0.4 mL Log in to see 12 to 15 Days
$375.38
Details
Mouse Goat Un-conjugated ELISA, WB 0.1 mg Log in to see 2 to 3 Days
$481.25
Details
Human Rabbit Un-conjugated IF, IHC (p), WB Confocal immunofluorescent analysis of CYP1A2 Antibody (Center) (ABIN655272) with 293 cell followed by Alexa Fluor® 488-conjugated goat anti-rabbit lgG (green). DAPI was used to stain the cell nuclear (blue). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Mouse Un-conjugated FACS, IHC, WB HEK293T cells transfected with either RC221636 overexpress plasmid (Red) or empty vector control plasmid (Blue) were immunostained by anti-CYP1A2 antibody (ABIN2453827), and then analyzed by flow cytometry. HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY CYP1A2 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 µg per lane) were separated by SDS-PAGE and immunoblotted with anti-CYP1A2. 100 μL Log in to see 2 to 3 Days
$423.50
Details
Human Mouse Un-conjugated FACS, WB 100 μL Log in to see 7 to 9 Days
$493.17
Details

CYP1A2 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Human , , , ,
, ,
,
, , , , , , , , , , , , , , , , , , ,
Mouse (Murine) , , , ,
, ,
,
, , , , , , , , , , , , , , , , , , ,
Rat (Rattus) , , ,
, ,
,
, , , , , , , , , , , , , , , , , , ,

Top referenced anti-CYP1A2 Antibodies

  1. Human Polyclonal CYP1A2 Primary Antibody for IHC (p), WB - ABIN3044117 : Fan, Jiang, Wang, Tan, Zeng, Wang, Chen, Qu, Gonzalez, Huang, Bi: Wuzhi tablet (Schisandra Sphenanthera extract) protects against acetaminophen-induced hepatotoxicity by inhibition of CYP-mediated bioactivation and regulation of NRF2-ARE and p53/p21 pathways. in Drug metabolism and disposition: the biological fate of chemicals 2014 (PubMed)
    Show all 2 Pubmed References

  2. Human Polyclonal CYP1A2 Primary Antibody for IHC (p), WB - ABIN3043820 : Jiang, Fan, Wang, Chen, Zeng, Tan, Gonzalez, Huang, Bi: Schisandrol B protects against acetaminophen-induced hepatotoxicity by inhibition of CYP-mediated bioactivation and regulation of liver regeneration. in Toxicological sciences : an official journal of the Society of Toxicology 2014 (PubMed)
    Show all 2 Pubmed References

  3. Human Polyclonal CYP1A2 Primary Antibody for Func, WB - ABIN2473165 : Mesa-Ramos, García Criado, Mellado Rider, Mesa-Ramos, Alfaro Rodríguez, Carpintero Benítez: Modifications of the normal sonographic image in gluteal fibrosis. in Acta orthopaedica Belgica 1992 (PubMed)
    Show all 2 Pubmed References

  4. Human Polyclonal CYP1A2 Primary Antibody for IF (p), IHC (p) - ABIN742470 : Huang, Duan, Zhao, Gao, Niu, Xu, Li: Reduction of Aflatoxin B1 Toxicity by Lactobacillus plantarum C88: A Potential Probiotic Strain Isolated from Chinese Traditional Fermented Food "Tofu". in PLoS ONE 2017 (PubMed)

  5. Mouse (Murine) Polyclonal CYP1A2 Primary Antibody for ELISA, WB - ABIN4302061 : Sulem, Gudbjartsson, Geller, Prokopenko, Feenstra, Aben, Franke, den Heijer, Kovacs, Stumvoll, Mägi, Yanek, Becker, Boyd, Stacey, Walters, Jonasdottir, Thorleifsson, Holm, Gudjonsson, Rafnar et al.: Sequence variants at CYP1A1-CYP1A2 and AHR associate with coffee consumption. ... in Human molecular genetics 2011 (PubMed)

More Antibodies against CYP1A2 Interaction Partners

Rabbit Cytochrome P450, Family 1, Subfamily A, Polypeptide 2 (CYP1A2) interaction partners

  1. CYP1A1 (show CYP1A1 Antibodies) and CYP1A2 localization into different lipid microdomains is governed by their N-terminal and internal protein regions

  2. Removal of cholesterol (an important constituent of ordered domains) led to the relocation of CYP1A2, CYP2B4 and CPR (show POR Antibodies) to the disordered regions.

  3. Oxidation kinetics of toluene in CYP1A2-CYP2B4 mixtures with and without cytochrome p450 reductase (CPR (show POR Antibodies)) are consistent with a model in which CYP1A2 has a higher affinity for CPR (show POR Antibodies) binding.

Human Cytochrome P450, Family 1, Subfamily A, Polypeptide 2 (CYP1A2) interaction partners

  1. findings suggest that CYP1A2 alleles or haplotypes were not predictive of metabolic phenotypes in the Nigerian population; carriers of CYP2A6 (show CYP2A6 Antibodies)*9/*17 genotype are likely to be poor metabolisers of CYP2A6 (show CYP2A6 Antibodies) substrates and may experience adverse reactions or poor efficacy while using drugs metabolised mainly by CYP2A6 (show CYP2A6 Antibodies)

  2. frequency of slow activity CYP1A2 enzyme alleles is very low among Emiratis which correlates with the presence of low frequencies of derived alleles in CYP1A2 gene

  3. Study provided additional evidence that CYP1A2 is an important susceptibility gene for essential hypertension.

  4. Studied diosmetin effect on signal pathway and apoptosis in HepG2 cells. Dios-induced cell apoptosis could be reversed by p53 (show TP53 Antibodies) blockade and the effects of Dios on cellular P53 (show TP53 Antibodies) and CYP1A1/CYP1A2 (show CYP1A1 Antibodies) proteins levels were examined. Found P53 (show TP53 Antibodies), CYP1A1 (show CYP1A1 Antibodies), and CYP1A2 proteins were up-regulated by diosmetin; p53 (show TP53 Antibodies) downregulation by pifithrin caused inhibition of apoptosis.

  5. the difference in clozapine levels between smokers and nonsmokers appeared to be significant in the individuals carrying the homozygous -163A allele (P=0.02). It was also found that nonsmokers carrying the -163A allele tended to have higher plasma levels of clozapine. Cigarette smoking has a significant impact on the plasma level of clozapine in schizophrenic patients carrying the homozygous -163A allele in the CYP1A2 gen (show GEN1 Antibodies)

  6. genetic association studies in population in Spain: Data suggest that an SNP in CYP1A2 (-163C>A; rs762551) is not associated with performance enhancement/visual attention effects in response to moderate caffeine consumption as dietary supplement (capsules) during exercise; C-allele carriers reported increased nervousness after caffeine ingestion.

  7. We conducted a genome-wide association study (GWAS) of plasma caffeine, paraxanthine, theophylline, theobromine and paraxanthine/caffeine ratio. A single SNP at 6p23 (near CD83 (show CD83 Antibodies)) and several SNPs at 7p21 (near AHR (show AHR Antibodies)), 15q24 (near CYP1A2) and 19q13.2 (near CYP2A6 (show CYP2A6 Antibodies)) met GW-significance (P < 5 x 10-8) and were associated with one or more metabolites

  8. We observed a strong dose-dependent increase in hair PhIP (show PHIP Antibodies) levels. This increase was highly correlated with dose received (rho = 0.68, P < 0.0001).CYP1A2 activity and normalizing for hair melanin did not modify the response to the intervention.

  9. findings indicated that the -3860 G > A polymorphism in CYP1A2 might not be a risk factor for lung cancer [meta-analysis]

  10. CYP1A2-163C/A polymorphism is associated with increased susceptibility to bladder cancer in the Chinese population.

Mouse (Murine) Cytochrome P450, Family 1, Subfamily A, Polypeptide 2 (CYP1A2) interaction partners

  1. our results suggest a more important contribution of CYP1A2 (show CYP1A1 Antibodies) to the in vivo plasma clearance and thus detoxification of 4-Aminobiphenyl

  2. hepatic CYP1A2 (show CYP1A1 Antibodies) plays a critical role in the attenuation of hyperoxic lung injury by decreasing lipid peroxidation and oxidative stress in vivo.

  3. Aryl hydrocarbon receptor (show AHR Antibodies) mediated induction of hepatic CYP1A1 (show CYP1A1 Antibodies)/1A2 is dependent on the presence of ctnnb1 (show CTNNB1 Antibodies).

  4. Results indicate Cyp1a2 (show CYP1A1 Antibodies) genotype is important in susceptibility to PCB (show PC Antibodies)-induced deficits in learning and memory.

  5. Miroestrol and deoxymiroestrol significantly up-regulated CYP2B9 while suppressing CYP1A2 (show CYP1A1 Antibodies) at both transcriptional and enzymatic levels.

  6. A report of uroporphyria development in Cyp1a2 (show CYP1A1 Antibodies)-/- mice additionally null for both alleles of the hemochromatosis (Hfe (show HFE Antibodies)) gene and heterozygous for deletion of the uroporphyrinogen decarboxylase (Urod (show UROD Antibodies)) gene (genotype: Cyp1a2 (show CYP1A1 Antibodies)-/-;Hfe (show HFE Antibodies)-/-;Urod (show UROD Antibodies)+/-).

  7. High levels of maternal hepatic CYP1A2 (show CYP1A1 Antibodies) protect against deficits in learning and memory in offspring exposed to a mixture of coplanar and noncoplanar PCBs; high-affinity AHR (show AHR Antibodies) is the next most important factor in protection of offspring.

  8. In rodents, aristolochic acid demethylation, mediated by CYP1A2 (show CYP1A1 Antibodies), is a primary pathway of aristolochic acid detoxication.

  9. The expression of Cyp1a1 (show CYP1A1 Antibodies), Cyp1a2 (show CYP1A1 Antibodies), and OGG1genes was significantly up-regulated in mice given diets containing 375 ppm dicyclanil or more.

  10. the TRE (show TREH Antibodies) element in E1 is essential for constitutive expression of the mouse Cypla2 gene

Pig (Porcine) Cytochrome P450, Family 1, Subfamily A, Polypeptide 2 (CYP1A2) interaction partners

  1. In the present study, CYP1A2 expression in liver increased in groups exposed to single exposures of 5 mgkg-bw- 1 (p = 0.044) and 20 mgkg-bw- 1 (p = 0.033) relative to controls

  2. This study demonstrated for the first time that the serum testosterone level is one of the physiological factors which regulate constitutive expression of hepatic CYP1A1 (show CYP1A1 Antibodies) and CYP1A2 in pigs.

  3. The findings demonstrate a gender-related difference in the constitutive expression of hepatic CYP1A2 in Meishan pigs and further indicate that testosterone down-regulates the constitutive gene expression of the enzyme.

  4. Purification, molecular cloning, heterologous expression and characterization of pig CYP1A2

  5. Effect of beta-napthoflavone on AHR (show AHR Antibodies)-related gene, CYP1A2, in the pig is reported.

CYP1A2 Antigen Profile

Protein Summary

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. The protein encoded by this gene localizes to the endoplasmic reticulum and its expression is induced by some polycyclic aromatic hydrocarbons (PAHs), some of which are found in cigarette smoke. The enzyme's endogenous substrate is unknown\; however, it is able to metabolize some PAHs to carcinogenic intermediates. Other xenobiotic substrates for this enzyme include caffeine, aflatoxin B1, and acetaminophen. The transcript from this gene contains four Alu sequences flanked by direct repeats in the 3' untranslated region.

Gene names and symbols associated with CYP1A2

  • cytochrome P450 1A2 (VDBG_06455) antibody
  • cytochrome P450 1A2 (CYP1A2) antibody
  • cytochrome P450 1A2-like (LOC101825565) antibody
  • cytochrome P450 LM4 (LOC100328937) antibody
  • cytochrome P450, family 1, subfamily A, polypeptide 2 (CYP1A2) antibody
  • cytochrome P450, family 1, subfamily a, polypeptide 2 (Cyp1a2) antibody
  • CP12 antibody
  • CP450 antibody
  • CYP-IA2 antibody
  • Cyp1a1 antibody
  • CYP1A2 antibody
  • CYPD45 antibody
  • CYPIA-2 antibody
  • CYPIA2 antibody
  • P-450d antibody
  • P3-450 antibody
  • P450(PA) antibody
  • P450-3 antibody
  • P450-PM4 antibody
  • RATCYPD45 antibody

Protein level used designations for CYP1A2

cytochrome P450 1A2 , CYPIA2 , Cytochrome P450-MC4 , Hepatic cytochrome P-450MC1 , cytochrome P-450 form 4 , cytochrome P-450IA2 , pulmonary cytochrome P-450MC1 , P450 LM4 , P450 isozyme 4 , cytochrome P450 isozyme 4 , cytochrome P450-PM4 , P450 form 4 , aryl hydrocarbon hydroxylase , cytochrome P(3)450 , cytochrome P450 4 , cytochrome P450, subfamily I (aromatic compound-inducible), polypeptide 2 , cytochrome P450-P3 , dioxin-inducible P3-450 , flavoprotein-linked monooxygenase , microsomal monooxygenase , xenobiotic monooxygenase , aromatic compound inducible , cytochrome P450 family 1 subfamily a polypeptide 1 , cytochrome P450, 1a2, aromatic compound inducible , cytochrome P450-P2 , Cytochrome P450 subfamily I (aromatic compound-inducible) member A2 (Q42 form d) , P-448 , P450-D , cytochrome P-448 , cytochrome P-450d , cytochrome P450, 1a2 , cytochrome P450, subfamily I (aromatic compound-inducible), member A2 (Q42, form d) , cytochrome P450-D

GENE ID SPECIES
9536166 Verticillium alfalfae VaMs.102
554345 Felis catus
101825565 Mesocricetus auratus
100328937 Oryctolagus cuniculus
1544 Homo sapiens
13077 Mus musculus
24297 Rattus norvegicus
414856 Gallus gallus
494010 Canis lupus familiaris
100135513 Cavia porcellus
100152910 Sus scrofa
100172368 Pongo abelii
100392712 Callithrix jacchus
Selected quality suppliers for anti-CYP1A2 (CYP1A2) Antibodies
Did you look for something else?