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CYP1B1 encodes a member of the cytochrome P450 superfamily of enzymes. Additionally we are shipping CYP1B1 Kits (16) and CYP1B1 Proteins (5) and many more products for this protein.
Showing 10 out of 124 products:
Human Polyclonal CYP1B1 Primary Antibody for EIA, WB - ABIN360259
Suri, Kalhor, Zargar, Nilforooshan, Yazdani, Nezari, Paylakhi, Narooie-Nejhad, Bayat, Sedaghati, Ahmadian, Elahi: Screening of common CYP1B1 mutations in Iranian POAG patients using a microarray-based PrASE protocol. in Molecular vision 2008
Show all 3 references for ABIN360259
Human Polyclonal CYP1B1 Primary Antibody for WB - ABIN2784612
Wang, Hawkins, Miller: Aryl hydrocarbon receptor-mediated up-regulation of ATP-driven xenobiotic efflux transporters at the blood-brain barrier. in FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2011
Show all 2 references for ABIN2784612
either absent or very low CYP1B1 activity levels are the primary molecular defect involved in primary congenital glaucoma pathogenesis.
3 polymorphisms, rs10012, rs1056827, and rs150799650 in the CYP1B1 gene correlate with urinary bladder cancer significantly in the Indo (show IDO1 Antibodies)-European population of Uttar Pradesh, India.
the single nucleotide polymorphisms rs180040 and rs1056827 of CYP1B1 showed an association with risk of primary open-angle glaucoma (Meta-Analysis)
African-American women, the CYP1B1 SNP rs162561 was associated with right ventricular ejection fraction.
CYP1B1 genetic polymorphisms may influence outcome of taxane therapy in Roma and Hungarian populations.
Results show that CYP1B1 may promote renal cell carcinoma (show MOK Antibodies) development by inducing CDC20 (show CDC20 Antibodies) expression and inhibiting apoptosis through the down-regulation of DAPK1 (show DAPK1 Antibodies).
The rate of CYP1B1 mutations in Lebanese patients with primary congenital glaucoma (PCG) is lower than that reported in other Arab and Middle Eastern populations and suggests other genes are responsible.
This dysmorphic girl is Saudi Arabian and has CYP1B1-negative primary congenital glaucoma suggests that her glaucoma phenotype is related to her de novo copy number variation.
data suggests that CYP1B1 promotes cell proliferation and metastasis by inducing EMT (show ITK Antibodies) and Wnt (show WNT2 Antibodies)/beta-catenin (show CTNNB1 Antibodies) signaling via Sp1 (show PSG1 Antibodies) induction
drugs acting as D2-dopamine receptor (show DRD2 Antibodies) antagonists can modify several hormone systems that regulate the expression of CYP1A1 (show CYP1A1 Antibodies), CYP1A2 (show CYP1A2 Antibodies) and CYP1B1, and may affect the toxicity and carcinogenicity outcome of numerous toxicants and pre-carcinogenic substances
hypertension, and associated pathogenesis in ApoE (show APOE Antibodies)(-/-)/Cyp1b1(+/+) mice on an atherogenic diet are most likely dependent on CYP1B1-generated oxidative stress and increased plasma lipid levels independent of blood pressure and absorption of lipids.
Follicle stimulating hormone functions via p38 MAPK (show MAPK14 Antibodies)-induced dephosphorylation at Ser (show SIGLEC1 Antibodies)(727) of STAT1 (show STAT1 Antibodies) to downregulate Cyp1b1 expression and maintain the estradiol levels in mouse dominant follicles.
Cyp1b1 contributes to angiotensin II induced hypertension and its pathogenesis in male mice.
Suggest that Cyp1b1 plays a critical role in female mice in protecting against renal dysfunction and end-organ damage associated with ANG II (show AGT Antibodies)-induced hypertension.
Data indicaate that adduct formation in cytochrome P450 (show CYP Antibodies) Cyp1b1 knockout mice was significantly reduced compared to wild-type mice receiving dibenzo[def,p]chrysene (DBC).
Cyp1b1 deletion substantially alters the expression of genes associated with fatty acid homeostasis
Data indicate that hepatic stearoyl-CoA desaturase 1 (SCD1) expression was decreased in cytochrome P450 1B1 (CYP1B1)-null mice.
Using inhibitors of p38 (show CRK Antibodies) and MSKs, as well as mouse embryonic cells derived from p38alpha (show MAPK14 Antibodies)-deficient and MSK1 (show RPS6KA5 Antibodies)/2 double knockout mice, we show here that TNF-alpha (show TNF Antibodies) potentiates CYP1B1 upregulation via the p38 (show CRK Antibodies)/MSK1 (show RPS6KA5 Antibodies) kinase cascade
a direct role for mitochondrial CYP1B1 in PAH-mediated oxidative and chemical damage to mitochondria.
Cyp1B1 expression in vascular cells plays an important role in the regulation of the cellular reductive state, thrombospondin (TSP)2 (show THBS2 Antibodies) expression, and NF-kappaB (show NFKB1 Antibodies) activation.
CYP1B1 knockdown studies show CYP1B1 is not a significant factor in causing synergistic toxicity of PAHs, nor, in contrast to CYP1A, in providing protection
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. The enzyme encoded by this gene localizes to the endoplasmic reticulum and metabolizes procarcinogens such as polycyclic aromatic hydrocarbons and 17beta-estradiol. Mutations in this gene have been associated with primary congenital glaucoma\; therefore it is thought that the enzyme also metabolizes a signaling molecule involved in eye development, possibly a steroid.
cytochrome P450 1B1
, cytochrome P450, family 1, subfamily B, polypeptide 1
, aryl hydrocarbon hydroxylase
, cytochrome P450, subfamily I (dioxin-inducible), polypeptide 1 (glaucoma 3, primary infantile)
, flavoprotein-linked monooxygenase
, microsomal monooxygenase
, xenobiotic monooxygenase
, benz[a]anthracene inducible
, cytochrome P450, 1b1, benz[a]anthracene inducible
, cytochrome P450CMEF
, cytochrome P450EF
, cytochrome P450, subfamily 1B, polypeptide 1
, cytochrome P450RAP
, cytochrome P4501B