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Cytochrome P450, Family 17, Subfamily A, Polypeptide 1 (CYP17A1) ELISA Kits

CYP17A1 encodes a member of the cytochrome P450 superfamily of enzymes. Additionally we are shipping Cytochrome P450, Family 17, Subfamily A, Polypeptide 1 Antibodies (111) and Cytochrome P450, Family 17, Subfamily A, Polypeptide 1 Proteins (5) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
CYP17A1 1586 P05093
CYP17A1 13074 P27786
CYP17A1 25146 P11715
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Top Cytochrome P450, Family 17, Subfamily A, Polypeptide 1 ELISA Kits at antibodies-online.com

Showing 6 out of 9 products:

Catalog No. Reactivity Sensitivity Range Quantity Supplier Delivery Price Details
Rat 6.25 pg/ml 25-1600 pg/mL 96 Tests Log in to see 11 to 13 Days
$910.56
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Human
96 Tests Log in to see 6 Days
$528.57
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Mouse
96 Tests Log in to see 11 to 13 Days
$875.60
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Cow
96 Tests Log in to see 11 to 13 Days
$1,029.60
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Pig
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$1,029.60
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Chicken
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$1,095.60
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More ELISA Kits for Cytochrome P450, Family 17, Subfamily A, Polypeptide 1 Interaction Partners

Zebrafish Cytochrome P450, Family 17, Subfamily A, Polypeptide 1 (CYP17A1) interaction partners

  1. Data show that cytochrome P450 (show CYP ELISA Kits) enzymes Cyp17-I, Cyp11c1 (show CYP11B2 ELISA Kits), Cyp19a1a and Cyp19a1b and one of their regulators forkhead protein (show FOXO4 ELISA Kits) Foxl2a were detected both in the testis and ovary.

  2. In vivo, clotrimazole induced a concentration-dependent increase of cyp17a1 gene expression and Cyp17-I protein synthesis in zebrafish testis.

  3. Effects of sexual steroids on the expression of foxl2 (show FOXL2 ELISA Kits) in Gobiocypris rarus

  4. the enzyme P450c17 seemed to be expressed in ovary and non-gonadal tissues including the brain, gill, liver and intestine

Pig (Porcine) Cytochrome P450, Family 17, Subfamily A, Polypeptide 1 (CYP17A1) interaction partners

  1. The immunolocalization of P450c17, detected in the ovaries of pregnant pigs and fetal porcine gonads, indicates the potential sites of androgen synthesis.

  2. LH and insulin (show INS ELISA Kits) stimulate transcription of -976/+31 bp 5 (show HSPD1 ELISA Kits)'-upstream cis (show CISH ELISA Kits)-acting region of porcine CYP17 gene. Maximal transcriptional responsiveness requires proximal Sp1 (show SP1 ELISA Kits) and AP-2-like sequences -193 to -180 bp 5 (show HSPD1 ELISA Kits)' upstream of transcriptional start site.

  3. Synthesis of androstenone in pig testis is not directly affected by any polymorphisms in the coding region of the porcine CYP17 gene.

  4. effect of substrate on the redox potential for each P450c17 was measured in the presence of pregnenolone, progesterone, 17alpha-hydroxypregnenolone and 17alpha-hydroxyprogesterone

  5. These results demonstrate the differential effects of two forms of CYB5 (show CYB5A ELISA Kits) on the three activities of porcine CYP17A1 and show that CYB5B (show CYB5B ELISA Kits) does not stimulate the andien-beta synthase activity of CYP17A1.

Human Cytochrome P450, Family 17, Subfamily A, Polypeptide 1 (CYP17A1) interaction partners

  1. CYP17A1 rs3824755 and rs743572 are associated with Alzheimer's disease in the Chinese Han population and act in combination with APOE (show APOE ELISA Kits) e4.

  2. Data indicate that cytochrome P450 17A1 (CYP17A1) first catalyzes pregnenolone (PREG) and then converts the 17-hydroxypregnenolone initial product to dehydroepiandrosterone, a process representing the first committed step in the biosynthesis of androgens.

  3. Polymorphism single nucleotide of CYP17A1 gene is implicated to the development of high blood pressure.

  4. The FMN (show FMN1 ELISA Kits) domain outcompetes b5 for binding to CYP17A1 in the three-component system

  5. Our study suggests no strong association between the CYP17A1 T27C and LEP (show LEP ELISA Kits) -2548G>A polymorphisms and the incidence of breast cancer in Turkish women.

  6. Interaction of novel oxazoline derivatives of 17(20)e-pregna-5,17(20)-diene with cytochrome P450 17A1

  7. We conclude that cytochrome b5 (show CYB5A ELISA Kits) can influence the electronic conductivity of cytochrome P450c17 via allosteric, protein-protein interactions.

  8. genetic variants in the androgen-related genes CYP17A1 and JMJD1C might be associated with risk of Barrett's esophagus (BE) and esophageal adenocarcinoma (EAC (show CYLD ELISA Kits)).

  9. Thus, CYP17A1 may contribute to cardiac hypertrophy in this clinical condition.

  10. CYP17A1 mutation is associated with 17alpha-Hydroxylase/17-20 lyase deficiency leading to congenital adrenal hyperplasia.

Cow (Bovine) Cytochrome P450, Family 17, Subfamily A, Polypeptide 1 (CYP17A1) interaction partners

  1. BMP6 (show BMP6 ELISA Kits) has a role in downregulating INSL3 (show INSL3 ELISA Kits) and CYP17A1 and other proteins that modulate ovarian androgen production

  2. The binding of SF-1 (show NR5A1 ELISA Kits) to the CYP17 and StAR promoter regions increased in theca cells incubated with low levels of luteinizing hormone.

  3. Data suggest that the upstream region of gene encoding CYP17 contains unique cAMP-responsive sequence and appears to bind unique nuclear proteins or transcription factors in adrenal cortex. [REVIEW]

  4. the bovine genome contains three paralogous copies of the CYP17A1 gene, of which two (CYP17A1b and CYP17A1x) might be silenced by epigenetic modification (promoter methylation).

  5. Granulosa and theca of well-characterized large bovine follicles were isolated before and after the LH surge. CYP19A1 (show CYP19A1 ELISA Kits), HSD3B1 (show HSD3B1 ELISA Kits), and CYP17A1 transcripts were quantified by real-time PCR (qPCR) and the chromatin condensation was determined.

  6. effect of substrate on the redox potential for each P450c17 was measured in the presence of pregnenolone, progesterone, 17alpha-hydroxypregnenolone and 17alpha-hydroxyprogesterone [P450c17]

  7. Serum free culture conditions significantly enhanced Cyp17 and Csh1 but not Hsd3b (show HSD3B1 ELISA Kits) expression in trophoblast.

Mouse (Murine) Cytochrome P450, Family 17, Subfamily A, Polypeptide 1 (CYP17A1) interaction partners

  1. TRalpha (show GNAT1 ELISA Kits)/T3 directly acts on the P450c17 promoter, which contains putative thyroid response elements, and indirectly acts on the promoter of steroidogenic enzyme genes by modulating Nur77 (show NR4A1 ELISA Kits) transactivation on these promoters.

  2. ata indicate that androgen receptor (AR (show AR ELISA Kits)) regulation on Klk27, Rhox5, Eppin, and Cyp17 genes in adult mouse testis using chromatin immunoprecipitation (ChIP) assays.

  3. Data suggest that newly synthesized protein(s) are required for cAMP induction of CYP17 and 3-beta-HSD (show HSD3B1 ELISA Kits) mRNA levels (but not of CYP11A (show CYP11A1 ELISA Kits) mRNA levels). [REVIEW]

  4. Data suggest that immune-activation of testicular interstitial macrophages may cause inhibition of P450c17 gene expression in Leydig cells.

  5. Mamld1 (show MAMLD1 ELISA Kits) enhances Cyp17a1 expression primarily in Leydig cells and permit to produce a sufficient amount of testosterone for male sex development, independently of the Hes3 (show HES3 ELISA Kits)-related non-canonical Notch (show NOTCH1 ELISA Kits) signaling

  6. Fxr (show NR1H4 ELISA Kits)-/-Shp (show LAMC1 ELISA Kits)-/- mice exhibited cholestasis and liver injury as early as 3 weeks of age with strong induction of cytochrome P450 (show CYP ELISA Kits), family 17, subfamily a (show CYP ELISA Kits), polypeptide 1 (show CYP ELISA Kits) (Cyp17a1)

  7. Pubertal Cd exposure markedly reduced mRNA and protein levels of testicular StAR, P450scc (show CYP11A1 ELISA Kits), P450 (show POR ELISA Kits)(17alpha) and 17beta-HSD (show HSD17B1 ELISA Kits) in mice.

  8. cAMP induces expression of Cyp17 by a PKA-mediated mechanism which is inhibited by MIS (show AMH ELISA Kits) signal transduction

  9. CYP17, in addition to its 17alpha-hydroxylase/17,20-lyase activity, critical in androgen formation, also expresses a secondary activity, squalene monooxygenase (show SQLE ELISA Kits) (epoxidase).

  10. CYP17 deletion causes infertility in male.

Cytochrome P450, Family 17, Subfamily A, Polypeptide 1 (CYP17A1) Antigen Profile

Antigen Summary

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum. It has both 17alpha-hydroxylase and 17,20-lyase activities and is a key enzyme in the steroidogenic pathway that produces progestins, mineralocorticoids, glucocorticoids, androgens, and estrogens. Mutations in this gene are associated with isolated steroid-17 alpha-hydroxylase deficiency, 17-alpha-hydroxylase/17,20-lyase deficiency, pseudohermaphroditism, and adrenal hyperplasia.

Gene names and symbols associated with CYP17A1

  • cytochrome P450 17A1 (CpipJ_CPIJ010537) antibody
  • cytochrome P450 17A1 (CpipJ_CPIJ010543) antibody
  • cytochrome P450 17A1 (PTRG_02047) antibody
  • cytochrome P450, family 17, subfamily A, polypeptide 1 (cyp17a1) antibody
  • steroidogenic cytochrome P450 17-hydroxylase/lyase (cyp17) antibody
  • cytochrome P-450 17 alpha-hydroxylase/C17,20-lyase (CYP17A1) antibody
  • cytochrome P450 17A1 (CYP17A1) antibody
  • cytochrome P450, family 17, subfamily A, polypeptide 1 (CYP17A1) antibody
  • cytochrome P450, family 17, subfamily a, polypeptide 1 (Cyp17a1) antibody
  • cytochrome P450c17 (CYP17A1) antibody
  • CPT7 antibody
  • Cyp17 antibody
  • cyp17a1 antibody
  • CYPXVII antibody
  • P450-C17 antibody
  • p450c17 antibody
  • P45017A1 antibody
  • S17AH antibody
  • wu:fi13g04 antibody
  • wu:fi17b11 antibody
  • wu:fi31c08 antibody
  • zgc:66494 antibody
  • zgc:136516 antibody

Protein level used designations for CYP17A1

cytochrome P450 17A1 , steroid 17-alpha-hydroxylase/17,20 lyase , CYPXVII , cytochrome P450c17 , cytochrome P450-C17 , cytochrome P450 XVIIA1 , steroid 17-alpha-monooxygenase , steroidogenic cytochrome P450 17-hydroxylase/lyase , Cytochrome P450 17A1 , Steroid 17-alpha-hydroxylase/17,20 lyase , cytochrome P450 steroid 17-alpha-hydroxylase/17,20 lyase , cytochrome P450, family 17, subfamily A, polypeptide 1 , 17-alpha-hydroxyprogesterone aldolase , 17-alpha-hydroxylase cytochrome P450 , cytochrome P450, subfamily XVII (steroid 17-alpha-hydroxylase), adrenal hyperplasia , cytochrome p450 XVIIA1 , cytochrome P450 steroid 17alpha-hydroxylase/17,20 lyase , cytochrome P450, subfamily XVII , steroid 17-alpha-hydroxylase , cytochrome P450, 17 , cytochrome P450, 17a1 , steroid 17-alpha hydroxylase , Cytochrome P450, subfamily XVII , P450-C17 , P45017alpha , P450c17 , cytochrome P450, subfamily 17 , cytochrome P450 17 alpha-hydroxylase

GENE ID SPECIES
6043058 Culex quinquefasciatus
6043064 Culex quinquefasciatus
6339667 Pyrenophora tritici-repentis Pt-1C-BFP
100137017 Oncorhynchus mykiss
100313515 Ictalurus punctatus
399692 Danio rerio
100036774 Xenopus laevis
100145650 Xenopus (Silurana) tropicalis
100034232 Equus caballus
403330 Sus scrofa
1586 Homo sapiens
477807 Canis lupus familiaris
493967 Felis catus
281739 Bos taurus
13074 Mus musculus
25146 Rattus norvegicus
425056 Gallus gallus
493968 Ovis aries
450141 Pan troglodytes
678693 Macaca mulatta
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