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CYP2A13 encodes a member of the cytochrome P450 superfamily of enzymes. Additionally we are shipping CYP2A13 Antibodies (35) and many more products for this protein.
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CYP2A13 levels in human lungs can be suppressed by disease-associated inflammation in tissue donors.
an etiologically relevant interaction between CYP2A13 and ABCB1 (show ABCB1 Proteins) associated with lung cancer was analysed
The transgenic CYP2A13 is active.
CYP2A13 played a critical role in AFB1-induced neoplastic transformation.
Data suggest important role of CYP2A13 in AFG1 (show LACE1 Proteins)- (aflatoxin G1)-induced cytotoxicity, DNA damage, and activation of signal pathways in bronchial epithelium; data suggest similarities in CYP2A13-catalyzed bioactivation of AFG1 (show LACE1 Proteins) and AFB1 (aflatoxin B1).
CYP2A13 is efficient in 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone bioactivation in vivo and it can mediate 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone-induced lung tumorigenesis.
Findings suggest the potential involvement of pulmonary CYP2A13 in the early occurrence of NSCLC as well as in the development of EGFR (show EGFR Proteins) gene mutations.
an efficient approach for expressing functionally characterized, highly active and homogeneous CYP2A13 proteins.
CYP2A13 plays an important role in low-concentration AFB1-induced DNA damage, possibly linking environmental airborne AFB1 to genetic injury in the human respiratory system.
Findings suggest that CYP2A13 plays an important role in low-concentration AFB1-induced DNA damage, possibly linking environmental airborne AFB1 to genetic injury in human respiratory system.
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum. Although its endogenous substrate has not been determined, it is known to metabolize 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone, a major nitrosamine specific to tobacco. This gene is part of a large cluster of cytochrome P450 genes from the CYP2A, CYP2B and CYP2F subfamilies on chromosome 19q.
cytochrome P450 2A13
, cytochrome P450, subfamily IIA (phenobarbital-inducible), polypeptide 13
, cytochrome P450, family 2, subfamily A, polypeptide 13
, cytochrome P450 family 2 subfamily A polypeptide 13